Jacky Akhter

[Massimo @Rainmaker1973]

Researchers have uncovered a previously unknown immune structure located within the human skull.

A team of biologists from Washington University School of Medicine in St. Louis has located an overlooked immune organ embedded in the bone marrow of the cranium. For many years scientists assumed that the brain’s protective immune mechanisms operated in complete isolation from the rest of the body, thereby shielding delicate neural tissue from potentially harmful immune activity.

The new findings demonstrate that minute vascular passages extend from the brain, cross the outermost protective membrane, and connect directly with the marrow inside the skull.

Using these pathways, the investigators followed molecular signals into formations that closely resemble the germinal centers of lymph nodes. These sites function as specialized training zones in which immune cells proliferate, identify targets, and prepare to combat invaders at the earliest stage of an assault.

To examine the practical importance of the system, the scientists altered the lymphoid formations in mice bearing glioma, an especially aggressive form of brain cancer. When they stimulated the skull-based immune centers by applying a hydrogel containing specific proteins beneath the scalp, the animals mounted a markedly stronger anti-tumor response and lived significantly longer. In contrast, interference with the same structures allowed the tumors to expand without restraint.

Because comparable follicular helper T cells have already been observed in human skull marrow, the investigators believe analogous defensive hubs are present in people. Should further work confirm this, the discovery may transform treatment approaches for brain tumors, Alzheimer’s disease, and Parkinson’s disease by enabling physicians to stimulate cranial immune centers non-invasively through the scalp and thereby avoid invasive brain operations.

[Park, Jang Hyun, et al. “Functional Role of Skull Lymphoid Structures in CNS Immunosurveillance.” Nature (2026). DOI: 10.1038/s41586-026-10951-4]

[Swathi Prabhu, MD @Swathiprabhu5]

Whats happening here?
#GitHub #gastrointestinalpathology

[Daily Harry Potter @TheDailyHPotter]

The actors from the Harry Potter films are passing the baton to the new actors of the HBO series 🎭

[𝓝𝓲𝓴𝓴𝓲 𝓑𝓪𝓻𝓷𝓮𝓼 @NikkiBarnes]

Best explanation I’ve heard about US interests in Venezuela today.

P.S. She recorded this over 2 weeks ago.

[Dr. Bui Pathologist🌼 @DrBuiPathology]

I’m humbled & honored to be elected to serve my 2nd term as the Vice Speaker of the House of Delegates & an ex officio member of the Board of Governors of the CAP at #CAP24. Congratulations to the new HOD Steering Committee members! ⁦@Pathologists⁩ ⁦⁦@MoffittNews⁩

[Dr. Bui Pathologist🌼 @DrBuiPathology]

🎤Just in case you missed our live webinar, please give a listen 🎧 of the below recording + Q & A:

https://t.co/RtxmPrNmbx

⁦@dpatweet⁩ #AI #Pathology ⁦@Pathologists⁩ ⁦⁦@MoffittNews⁩ ⁦@CAPA_comm⁩ ⁦@captodayonline⁩ #pathtwitter #PathX #digital

[CAP Foundation @CAPFndn]

Congratulations to our CAP Foundation Board President, Dr. Bharati Jhaveri’s Swear In Ceremony!

[Jacky Akhter @fenzonima]

@Pathologists @MoffittNews
What a wonderful and successful conference! So happy to represent Moffitt and also learn from so many wonderful presenters!!

[Jacky Akhter @fenzonima]

@Pathologists @Pathoutlines
Has been such a useful tool throughout residency and fellowship! Thanks for all of your hard work!

[Jacky Akhter @fenzonima]

@Pathologists small world!! CAP is a great place for reunions!! Meeting up with colleagues from my residency!!

[Jacky Akhter @fenzonima]

@Pathoutlines #CAP24

[Dr. Patrick Hwu @PatrickHwuMD]

With the #cytology team! #LabWeek2024

[Dr. Patrick Hwu @PatrickHwuMD]

Did you know it's #LabWeek? I recently had the chance to chat with our cytology team about their work. #Cytology is the microscopic study of cells to detect cancer and other abnormalities. Thank you Lauren for the great walkthrough - your work is critical to our mission @MoffittNews. Please join me in celebrating all our lab and pathology professionals during #LabWeek2024!

[Dr. Patrick Hwu @PatrickHwuMD]

Breakfast with our #pathology fellows @MoffittNews this morning. Our pathologists and their teams are the unsung heroes of #oncology — but we could not treat our patients and have the outcomes we do without them! #LabWeek2024 #LabWeek

[Jacky Akhter @fenzonima]

Urine cytology @Pathologists

[Jacky Akhter @fenzonima]

Learning from the best!! @Pathologists #CAP23

[Jacky Akhter @fenzonima]

#cap23

[Jacky Akhter @fenzonima]

Congrats!! @ALBoothMD @Pathologists

[Jacky Akhter @fenzonima]

Getting ready to celebrate @Pathologists

[Slava Bobrov @slava__bobrov]

Neuron vs viruses vs bacteria. Microorganisms size comparison:
#biology