Sherrin Jacob

Pathologist, PGY 3+2

[Arkana Laboratories @arkanalabs]

How long have we known about glomeruli? Today’s teaching point is offered in honor of Marcello Malpighi (1628-1694), the Italian anatomist who is credited with having published the world’s first accurate description of glomerular structure (Bologna, Italy 1666). We learn from those who teach us!  

Bellomo G. A short history of 'glomerulus'. Clin Kidney J. 2013 Apr;6(2):250-1. PMID: 26019863

Fogazzi GB. The description of the renal glomeruli by Marcello Malpighi. Nephrol Dial Transplant. 1997 Oct;12(10):2191-2. PMID: 9351094.

Image Credit (for oil painting, Malpighi): Wellcome Collection (https://t.co/1JSHuMW5J5)

#TeachingPoints #kidneypath #renal #pathology

[Sherrin Jacob @SherrinJacob]

Oh, beautiful little things worthy of appreciation! #PathX #PathTwitter

[Int Soc Dermpath @IntSocDermpath]

#Pathology #Histology #MedicalEducation #DermPath #Pathology #Dermatology #Intsocdermpath #MedEd

[Sherrin Jacob @SherrinJacob]

@pepeheffernan @kriyer68 @premcharles @DrRanasaleh @smlungpathguy @Histiocita @RibianszkyA @padmapathology1 @DrGeeONE @edusqo @kis_lorand @DrMarkOng @DrJuhlin @TotalCytopath @gcai1978 @Quique_rs @SumantaDas_7 Lymph node. Metastatic small cell carcinoma

[Sherrin Jacob @SherrinJacob]

@Raghav_Gupta10 @Path_AIIMSDelhi @DrGeetikaSingh1 Here’s a peek at the ribbon that goes on the copper grid. Beautiful world under the lens.

[Zemplén Pataki, MD, PhD @ZemplenPataki]

Palate. What is your diagnosis? 🔎

Poll below 🗳️👇

#PathPuzzle 🕵️‍♂️
@UMichPath #Pathology #PathX #PathTwitter

[Cancer Cytopathology @CancerCytopath]

New #OpenAccess review by N. Paul Ohori MD of @UPMCPathology et al details the fascinating history of PTC nuclei & summarizes the major events representing the paradigm shifts, classification system changes, and controversies: https://t.co/wtOPRCUr9M #CytoPath #ENTPath

[Sherrin Jacob @SherrinJacob]

A quick glance through confusion

[Charlie Herndon @DrCycloPath]

#PathQuiz 🔬🦴 #BonePath
10-year-old boy presents with anterior tibial bowing.

A) Fibrous Dysplasia
B) Low-grade central osteosarcoma
C) Adamantinoma of long bones
D) Osteofibrous Dysplasia

#Pathology #BonePath

[Miruna Popescu, MD @MirunaPopescu13]

A good 🔬clue to distinguish between mucocele-like lesion (MLL) vs. mucinous carcinoma is the frequent presence of neovascularization in the latter.

Dr. Nour Seige, challenges in breast pathology, Romanian National Congress of Anatomical and Molecular Pathology, First Edition, Bucharest, Romania

#breastpath #PathTwitter

[Sherrin Jacob @SherrinJacob]

@vi_monappa @AnupamaArya12 @kriyer68 @pepeheffernan @DrGeeONE @SumantaDas_7 @Jaysharav53 🤯 Better to have seen one here!! Thanks for the post

[Sherrin Jacob @SherrinJacob]

@Caetano_Pathol @SumantaDas_7 So beautiful!

[Sherrin Jacob @SherrinJacob]

Ever increasing spectrum of MUC4 positive lesions

[Sumanta Das @SumantaDas_7]

Adult male. Arm swelling. Frozen section.
#PathX #PathTwitter #BSTPath

[Sherrin Jacob @SherrinJacob]

@SumantaDas_7 Why does it look familiar 😛 Very nice case though✨

[Janira Navarro @Janiranavarro]

Metastases to Small Intestine

- Colonize surface mucosa, creating the impression of a "precursor"
- Asynchronous architecture and cytology
- Patchy surface involvement
- Predominantly intravascular distribution

Uterine (endometrioid) carcinoma metastatic to small intestine (pic 2)
Prostate cancer metastatic to small intestine (pics 3-4)

Always check history if available

Dr. Panarelli - 2025 Diagnostic Pathology Update #USCAP #PathX #PathTwitter

[Ankur Sangoi @slusagar]

adult human presents with perinephric mass, excised

[Sherrin Jacob @SherrinJacob]

Hands down; an important bookmark! 2026 seems to be on fire!

[Mark Ong @DrMarkOng]

I'm working on a teaching presentation on Hodgkin's lymphoma.

Picture below contains HRS-like cells from 9 different cases.

Which ones are classical Hodgkin's lymphoma and which ones are something else?

#hemepath #pathtwitter #pathology

[Sherrin Jacob @SherrinJacob]

If your new year resolution was to exercise, here’s a workout for the pathology brains!! Happy new year everyone!! ✨

[Sumanta Das @SumantaDas_7]

Happy New Year to everyone! First case of 2026.
Female in her 50s. Multiple mixed sclerotic and lytic lesions involving the thoracic spine and pelvis.
#PathX #PathTwitter #BSTPath

[Human Pathology @Human_Pathology]

New in #HumPathol: Colloid cysts of the third ventricle show consistent expression of PAX8 but lack other features of thyroid, müllerian or intestinal differentiation. https://t.co/b6XW9Qx95z #pathology #PathTwitter #PathX #neuropath

[Sumanta Das @SumantaDas_7]

Adult male. Cerebellar SOL. #PathX #PathTwitter #NeuroPath

[Sherrin Jacob @SherrinJacob]

A wonderful tweetorial to cover the bases. #PathX #PathTwitter

[Sumanta Das @SumantaDas_7]

The Epigenetic Engines of Cancer: Decoding the SWI/SNF Complex 🧬⚙️

From the brain (AT/RT) to the lung (SMARCA4-def) to the kidney (MRT). Different organs. Different ages. Same Molecular Culprit.

Why does the loss of one "Chromatin Remodeler" create the most aggressive, chemo-resistant tumors?

A Mega-Thread on SWI/SNF, SMARCA4, & INI1. 🧵👇
#PathX #PathTwitter #MedEd #Oncology