Does the brain change during pregnancy? You bet it does. How about doing 26 MRI scans on a single person pre-conception to 2 years post-partum. WOW! Laura Pritschet and colleagues nailed it with their new paper in @NatureNeuro.
Key Points:
- The authors point out that pregnancy is a period of profound hormonal and physiological changes.
- The authors did something incredible by mapping neuroanatomical changes in an individual from preconception through two years postpartum.
- Boom! There were pronounced decreases in gray matter volume and cortical thickness.
- There were increases in white matter microstructural integrity, ventricle volume and cerebrospinal fluid.
- There were few regions untouched by the 'transition to motherhood.'
My take: This study shows us how a single brain in a single person can be a powerful resource when scanned serially over time. This method is hard to pull off, however what it has the potential to teach us about neuroscience is mind-blowing. Though this paper is only a single subject, the data provides a comprehensive map of the human brain across gestation. It will be interesting to add to the dataset, so we can understand changes across multiple persons and multiple conditions. The convergence of evidence is revealing that pregnancy as associated with dramatic neuroplasticity. How about a shout out to this 38-year-old woman who underwent 26 MRI scans along with blood draws from 3 weeks preconception through 2 years postpartum!
https://t.co/LEnPHzKCcl #pregnancy #brain @ndosenbach@andreashorn_@EMiddlebrooksMD
🌟 Job Alert! We seek a Technical or Research Assistant to join our lab at @ESI_Frankfurt.
Assist us in neuroscience research with rats 🐀: train complex tasks, help with motion capture, brain recordings & more.
Apply before Feb 1, 2024! Please RT!
➡️ https://t.co/0t6cclSSbp
Join us and @buccino_alessio@spikeinterface@AllenInstitute on Nov 7th if you want learn about spike sorting from the experts with a follow-along tutorial covering best-practices for using the expansive SpikeInterface framework. Grab your spot here: https://t.co/mGAc3BwYnD
In two studies, we show that 'Language regions' and 'the language network' are the result of indiscriminate averaging (🗣️➗🧠), leaving only input regions and #connectivity hubs coordinating variable whole #brain distributions of activity: https://t.co/BQJDa5BjnS
#2 The position is supported by grant funding focused on the plasticity of cortico-cortical neural connections in young and elderly healthy humans. The position is for one year, with possibility of renewal.
😊Proud supervisor of @GuanHuang16 PhD candidate @WickingDementia 👏 Developed an amazing #Computer#vision model to detect #hand#gestures in real time! 👋👌 Outperforms state of the art models incl #yolo Check out this video example ⬇️✅️ in collaboration with @ict_utas
I’m really proud to share the second episode of @animals_how🐟🐠 that’s the first scientific podcast heard by my newborn child 👶🏻 she couldn’t start better! Thanks @FraLanzarini and @l_petrucco 🥰https://t.co/5e2FsT4uDu
THIRD EPISODE! ✨
We will talk about rats and their role in the neuroscientific research. Talking with Nacho (@neuroetho ) made me fall in love completely with these amazing animals. 🐀
https://t.co/FYrK2CLaCM
There is strong evidence support switching to refined mouse handling. Over 15 publications from independent labs show using tunnel handling or cupping to pick up mice improve mouse welfare, science, and handling. Learn more: https://t.co/ZPwfgiO7nX
#refine#NA3RsC#3Rs