Each single-cell image is a composite of the following channels:
Cyan: Mito-Dendra2
Red: EpCAM
Magenta: CD49f
Yellow: CD49b
Orange: Sca-1
Purple (dump): CD45, CD31, Ter119, Zombie dye
For more details, check out our paper at: https://t.co/LprdF7AD6N
Thank you @NatMetabolism for selecting my work for the cover of the May 2021 issue! I used #AmnisImageStream@Luminex to acquire thousands of single-cell images of mitochondria in the mammary epithelial cells from PhAM mice. @rmkhokha@KislingerThomas https://t.co/gIiSiKZ5g2
We then looked at the form and fxn of the #mitochondria (mito). LP had longer mito with defined cristae (where ETC is housed) and larger mito foci (teal dot = mito). Higher ETC proteins + optimal mito form enabled LP to have enhanced capacity for mito respiration (@ffalohy)/6
4yrs ago,@rmkhokha asked me to study the #metabolism of normal mammary epithelial cells for my MSc. Today, I share with you my 1st first-author pub in @NatMetabolism (https://t.co/C2H0uGzWB8).Below a thread on how studying normal cells helps us better understand #breastcancer. /1
I'm very excited to announce that my co-first paper with @mathepan & @c_mccloskey1 is finally out in @NatMetabolism! This paper wouldn't have been possible without our supervisors @rmkhokha & @KislingerThomas for their amazing support throughout the study. https://t.co/LprdF7AD6N
🎉Extremely excited to share this preprint from my post-doc work on #PancreaticCancer and #TME, where we discovered regional functional units in the PDAC TME and their specific and active roles in tumor pathobiology.
https://t.co/ZEFI4mQCMk
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So let me get this straight: Redditors rallying GameStop is market manipulation, but hedge fund billionaires shorting a stock is just an investment strategy?