Frederik Filip Stæger

Postdoc, Copenhagen University Hospital. Statistical and medical genetics.

[Frederik Filip Stæger @ffstaeger]

nogle af de genetiske undersøgelser, der er foretaget gennem de sidste >20 år i Grønland som del af befolkningsundersøgelserne.

Lyt med i morgen, hvis du er nysgerrig på, hvordan præcisionsmedicin har et større potentiale i Grønland end i andre lande. 2/2🧵

[Frederik Filip Stæger @ffstaeger]

Bedre og mere præcis behandling af diabetes i Grønland - hør hvordan arbejde fra min PhD nu bruges i klinikken og meget mere.

I morgen udgives podcasten 'Diabetesforskerne' som produceres af Steno Diabetes Centre. Jeg har fornøjelsen af at fortælle om ... 1/2🧵

[Frederik Filip Stæger @ffstaeger]

Final PhD-paper is now published in Bioinformatics. If you plan to genotype structural variants, then make sure to read our paper first. You will get fewer errors in your genotype calls and better genotype quality: https://t.co/cFf8dj4SnF

[Population and Statistical Genetics Group at UCPH @PopGenDK]

🧵1/5
Thought long-read sequencing had “solved” structural variant genotyping? We did. Turns out many SVs still have high genotype error rates with current tools. Our new method SVUPP uses long-read pre-phasing to reduce errors and improve genotype quality
https://t.co/vH3FFqFqYw

[Population and Statistical Genetics Group at UCPH @PopGenDK]

🧵1/5
Thought long-read sequencing had “solved” structural variant genotyping? We did. Turns out many SVs still have high genotype error rates with current tools. Our new method SVUPP uses long-read pre-phasing to reduce errors and improve genotype quality
https://t.co/vH3FFqFqYw

[Population and Statistical Genetics Group at UCPH @PopGenDK]

We sequenced and analyzed the world's rarest large mammal, the #saola. That turned into a cool paper substantially increasing what we know about this elusive animal, its evolutionary history, population structure, and long-term decline.
Check it out here: https://t.co/icyVNXTSz6

[Frederik Filip Stæger @ffstaeger]

@lpipes @Nature 🙏

[Frederik Filip Stæger @ffstaeger]

What started as a small side-project ended up being the main project of my PhD and is now published in @nature.com 🙏

[nature @Nature]

Nature research paper: Genetic architecture in Greenland is shaped by demography, structure and selection

https://t.co/3Iu3FrugoH

[Frederik Filip Stæger @ffstaeger]

Read the study highlights here:

[Population and Statistical Genetics Group at UCPH @PopGenDK]

The Greenlandic population offers significant potential for precision medicine. The largest analysis of its kind is now in @Nature. A big thank you to all participants in the health surveys throughout the last 25 years 🙏 https://t.co/A8i2jmFLEI 🧵1/6

[Nature News & Views @NatureNV]

Including under-represented groups in population genomics data could reduce inequalities in genetics-based clinical care and personalized medicine

https://t.co/xaEOgHKK2B

[nature @Nature]

Nature research paper: Genetic architecture in Greenland is shaped by demography, structure and selection

https://t.co/3Iu3FrugoH

[Frederik Filip Stæger @ffstaeger]

@Telegraph

[Layla Siraj, Ph.D. @LaylaSiraj]

Could not be more delighted to present our work investigating how over 220,000 complex and molecular trait-associated genetic variants affect transcriptional regulation using massively parallel reporter assays!
https://t.co/1eoN4OxAvd
See below for a 🧵. 1/n

[Population and Statistical Genetics Group at UCPH @PopGenDK]

New paper from our group, led by @renzobalb, @LauraDBertola and @AnnaBruniche, and with multiple collaborators!
"African bushpigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival" 🐖🧬🌍⛵️

[Andrew Vaughn @andrewhvaughn]

Happy to share a new preprint from the lab on ARGs, selection, and ancient DNA. https://t.co/xjJKTGFbWg We present CLUES2, a full-likelihood method that extends the work of Stern et al. 2019. Improvements include (1) the ability to use ARGs on ancient samples, allowing for 1/n

[The Nobel Prize @NobelPrize]

Historically, much of the gender gap in earnings could be explained by differences in education and occupational choices. However, this year’s economic sciences laureate Claudia Goldin has shown that the bulk of this earnings difference is now between men and women in the same occupation, and that it largely arises with the birth of the first child.

#NobelPrize

[Mikkel-Holger S. Sinding @MhsSinding]

Join us for the Arctic Science Outreach Day 2023.
7th of November at Greenland Science Week.
Series of engaging talks by esteemed scientists.
A window into the fascinating world of Arctic research.
Organised by @OutiTervo @marie__louis @MhsSinding
Founded by @Carlsbergfondet

[EPICconference @EPICconference]

Are you an evolutionary/population geneticist in Denmark? The 2nd EPIC conference will take place on 21-22 August 2023 in Copenhagen. Come along for two days of great talks and networking! #EPICdk23

Hosts: @BIO_UCPH @Globe_UCPH @PopGenDK
Register now at: https://t.co/oSMHCpADME

[bioRxiv @biorxivpreprint]

Insufficient evidence for natural selection associated with the Black Death https://t.co/2D8U6Dxvnf #bioRxiv

[Frederik Filip Stæger @ffstaeger]

Excited to see the finding in @LancetRH_Europe contributing to #equity in health care. #precisionmedicine

[NNF Center for Basic Metabolic Research (CBMR) @Metabolcenter]

New in @LancetRH_Europe 🧬 A genetic variant responsible for close to 7% of all cases of #diabetes in #Greenland has been discovered.

CBMRs Prof Torben Hansen led the research with with @UCPH_Research colleagues @idamoltke & @A_Albrechtsen.

Read more!👇

https://t.co/19CK8oDpn6

[NNF Center for Basic Metabolic Research (CBMR) @Metabolcenter]

New in @LancetRH_Europe 🧬 A genetic variant responsible for close to 7% of all cases of #diabetes in #Greenland has been discovered.

CBMRs Prof Torben Hansen led the research with with @UCPH_Research colleagues @idamoltke & @A_Albrechtsen.

Read more!👇

https://t.co/19CK8oDpn6