@Myeloma_Doc@Someone68423357 My wife was diagnosed in 2018 with PPCL. The BSABs have worked the best for her, tec for 18 months and tal for 20 and still SCR.
@RahulBanerjeeMD@vhugo8762@AjHematology Yessir! You are so very right on both counts! We have benefited from each of these. And we did Abecma and Tec without prophy Toci, then tal with it. Much, much preferred prophy rather than the days of fever before getting it.
@ThomasGoldkamp@delatorre Not sure about top 5 but I think the loudest was as Kerwin was limping towards the end zone for the 2 point conversion against Auburn in โ86.
@Transplant_Doc@RahulBanerjeeMD@SusanBal9@BloodPortfolio Tried to get my wife into this trial. Excluded due to PCL @ dx, never since. Started tal. Still SCR @ 20 mos. Could have been a great success story for arlo and found it works great for hard to treat patients. Please have a 2nd arm in all trials for those who are excluded.
@hhashmi87@Someone68423357 We tried to get my wife into this trial prior to going on tal but, unfortunately, she was excluded because she had PCL at dx and barely but never since. What a shame that these drug companies do this. They should have a second arm for the patients who are excluded. @Bristol_Myers
@HadidiSamer Thank you! Thatโs great news! My wife was last on daratumamab in 2020 and last on isatuximab in 2022. 48 months and counting since her last exposure to either of these. And both worked well.
@End_myeloma I totally agree! A another problem I see with trials is the number of patients who are excluded. There should be a second arm in all trials for those who are excluded.
@rajshekharucms I totally agree! You also shouldnโt accept trials with exclusions unless they are willing to have a second arm for those who are excluded.
@Papa_Heme@DrPaulyDeSantis@Dr_R_Kurzrock Thatโs awesome! It seems like a good idea. If it works for some of these patients, we may find that we really have something! And, with a second arm, no harm, no foul if it doesnโt work in that arm. Gonna need to know if these BCMA drugs work for those previously exposed.
@Myeloma_Doc Isnโt it time to include patients who have had BCMA CAR-T some time ago, say 3 years? We need to know if these drugs will work for this ever growing list of patients. Better yet, create a 2nd arm of the trial for those who are excluded.
@NWSTallahassee We have totaled .45 inches in the Ashville community of NE Jefferson County. It keeps skipping us. Iโm sure glad other folks are getting it. Fed hay to cattle yesterday. I hope to be finished feeding hay when February arrives in a normal year.
@HiraSMian@JoshuaRichterMD@RahulBanerjeeMD@OncLive@TischCancer Man. That really needs to change. It makes absolutely no sense to withhold drugs which would almost certainly help them for patients who have a disease with no cure. No sense, whatsoeverโฆ