Now out in @GenomeBiology!
HistoGWAS combines histology foundation models, statistical genetics and generative AI to characterize variant effects on tissue morphology, enabling genetic analysis at the tissue scale.
Led by @skc_2017@HelmholtzMunich@PioneerCampus
@JohnGolf_CA@MariosGeorgakis Exactly. The signal is already there at GTEx scale. Our simulations show that ~10K samples would detect variants explaining ~10× less variance. Scaling this opens the door to systematic mapping of disease loci effects on tissue architecture.
Now out in @GenomeBiology!
HistoGWAS combines histology foundation models, statistical genetics and generative AI to characterize variant effects on tissue morphology, enabling genetic analysis at the tissue scale.
Led by @skc_2017@HelmholtzMunich@PioneerCampus
📢 Deadline extension: RECOMB-Genetics 2026
The RECOMB-Genetics 2026 workshop will take place in Thessaloniki, Greece 🇬🇷 on May 25, 2026, as part of the RECOMB satellite meetings, just before the main RECOMB conference (May 26–29).
📅 Submission deadline: April 2 (AoE)
👉 https://t.co/1CxyO3KFWe
@RECOMBconf
Huge thanks to all co-authors and collaborators for their contributions. Daniel Sens, Ayshan Aliyeva, Shubham Chaudhary, Qiaohan Xu, Emmanuelle Salin, Johannes Schiefelbein, Ben Asani, Oana Veronica Amarie, Elida Schneltzer, @asegre, @ja_schnabel, @caina89
New preprint: REECAP, a framework using imaging foundation models for disease genetics analysis. We benchmark it against alternative image-derived representations and link loci to retinal morphology. Led by @shilova_lubov, collab with @BjoernEskofier.
🔗 https://t.co/ZNTb5NBWud
🚨 RECOMB-Genetics Deadline 🚨
The RECOMB-Genetics 2025 workshop is in Seoul 🌏 on April 25, 2025, just before the main RECOMB conference (April 26–29).
📅 Submission deadline: Feb 14, 2025 (AoE)
👉https://t.co/4AifuCsur6
Submit your work and join us for this exciting event!
🚨 RECOMB-Genetics Deadline 🚨
The RECOMB-Genetics 2025 workshop is in Seoul 🌏 on April 25, 2025, just before the main RECOMB conference (April 26–29).
📅 Submission deadline: Feb 14, 2025 (AoE)
👉https://t.co/4AifuCsur6
Submit your work and join us for this exciting event!
🚨 UPCOMING DEADLINES 🚨
⭐️Highlights: January 27, 2025
📋Posters: January 27, 2025
RECOMB-Seq: January 24 (abstracts)
RECOMB-Microbiome: January 31
RECOMB-P&E: February 5
RECOMB-CG: February 7
RECOMB-Genetics: February 14
RECOMB-CCB: February 14
https://t.co/rLiCgmclJ6
After 4 fantastic years of research, with @caina89 & @heinig_matthias, I’m thrilled to share the first tissue specific map of apparent mtDNA heteroplasmy in humans and their relationships with donor age and mtDNA gene expression across 49 human tissues!👇
https://t.co/bQ5rxhbMTX
Thrilled to announce that my group at @HelmholtzMunich and @PioneerCampus will contribute to the transformative scientific endeavor of advancing virtual cell models with @Tkaraletsos and @cziscience. Truly honored to collaborate with such a pioneering and brilliant team! 🧬🔬
We present MultiOrg: an #organoid dataset tailored for #object_detection tasks with #uncertainty quantification. Over 400 high-resolution 2D #microscopy images and multi-expert annotations of more than 60,000 organoids.
Paper: https://t.co/39WjGkSVF4
Data: https://t.co/64vBOSvPGi
Looking to enhance rare variant association testing? Catch my platform talk on FuncRVP - a Bayesian rare variant association framework leveraging functional gene embeddings.
Nov 7, 11:30-11:45, Room 501. #ASHG24
I’m thrilled to introduce MemBrain V2(https://t.co/YLuu6oKEqt), our latest research tool developed by @LorenzLamm and co-supervised by @bengeliscious, right here at the beautiful Princeton campus. It’s exciting to see how widely it’s being adopted by the community!
PhD students—Do this and 90% of your paper problems will disappear.
The secret to getting your papers accepted isn't what you think.
It's about...
10 rules to structure your papers like you mean business.
I wish I knew these when I started my PhD.
Here they are:
As a physicist-turned-AI scientist, I’m thrilled to see this! Physics principles are at the core of AI breakthroughs, and AI models are dynamic physical systems!!! 🌍🔬 #AI#Physics#NeuralNetworks#NobelPrize2024
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Physics to John J. Hopfield and Geoffrey E. Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks.”