Dr. Pierre Thibeault

Postdoctoral fellow at University of Toronto. Molecular pharmacologist - love all things GPCR. All opinions are my own. 🏳️‍🌈 he/him

[Bill Madden @maddenifico]

Trump has just destroyed the US beef industry. No country in their right mind is going to import US beef.

After Trump cut funding for Screwworm monitoring programs, the dangerous flesh-eating parasite has been found in US cattle for the first time since 1966.

[Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social @RolandDunbrack]

Very useful website to score PPI. Shows why you should NOT use ipTM - p53+MDM2 scores 0.3 in ipTM, but 0.75 in ipSAE, 0.67 in iLIS, 0.99 in actifpTM. Well-known interaction, already in AF2 training data. ipTM is low bc of large irrelevant domains and IDRs in BOTH proteins.

[Phil Pothen 🇨🇦 he/him @pothen]

Jeebus! 🤯

It's hard to see how any honest politician can now support moving even a step further towards commissioning a jet runway PROPOSAL for the Island, let alone actually lifting the ban on jets.

End this insanity NOW! (1/3)

[Tyler Watt 🇨🇦 @tylerwatt]

The Health Minister is either ignorant or lying - and neither option is acceptable.

She has personally overseen the expansion of private surgeries and private primary care in Ontario while claiming two-tier health care doesn't exist.

Instead of fixing the staffing crisis and investing in public health care, this government keeps pushing privatization and hoping nobody notices.

Ontarians aren't buying it. #onpoli
https://t.co/YyHe9MUsTI

[Dr. Pierre Thibeault @frenchnerd]

Oh again? What’s this - the 5 or 6 time it’s right on the cusp of being reopened?

[CNN Breaking News @cnnbrk]

President Donald Trump said Saturday that a broader agreement between the United States and Iran has been "largely negotiated," and announced that the Strait of Hormuz would be reopened, signaling potential momentum toward ending the monthslong war. https://t.co/tekzHnOvZX

[Donnelly Centre @DonnellyCentre]

Byu Ri Sim is the winner of the 2026 Jennifer Comyn Graduate Award for Cancer Research! Byu Ri is investigating how the hyperactive pathway signalling behind colorectal cancer cells can be exploited to identify new therapeutic avenues.

Read more here:
https://t.co/helHRVt5Uz

[Elizabeth Warren @SenWarren]

This is an unprecedented level of corruption.

Trump is forcing the government to drop ALL tax audits of him, his family, and his businesses—giving him FULL IMMUNITY from prosecution.

What is Trump hiding from the American people?

Congress must step up and stop this corruption.

[Spencer Hakimian @SpencerHakimian]

Trump was just given a blanket pardon from the IRS for any past, present, or future tax crimes.

[Dr. Pierre Thibeault @frenchnerd]

@WestJet you cancelled a full flight 20 mins before boarding and have given us no information or options. So we’re just waiting here with completely unhelpful staff wondering how we will get home.

[Jonathan O’Callaghan @Astro_Jonny]

Astronomers have waited years for Rubin to come online.

Now a trickle of data has begun to flow down before the floodgates open, with discoveries already being made.

“It almost doesn’t feel real”

Story by me in @QuantaMagazine

https://t.co/lsSty0TV7j

[Dr. Pierre Thibeault @frenchnerd]

Please let me know where and how I can report a food safety issue.

[Dr. Pierre Thibeault @frenchnerd]

@costcocanada I can’t get help on your online chat because they say I need to find the right part of Costco to talk to. I was eating one of your stocked items and bit down on a huge chunk of bone. I’m trying to report a food safety issue here and can’t get any assistance…

[Colin D'Mello | Global News @ColinDMello]

NEW: An advocacy group is planning to file a constitutional challenge to Ontario’s freedom of information clampdown, arguing it breaches the right of voters to be informed for a meaningful debate about public issues.

https://t.co/4saPiQQQ0x

#onpoli

[Dr. Pierre Thibeault @frenchnerd]

I am noticing a trend in the job boards where TT jobs are looking for an expert in whatever area “AND AI”. how are people meeting the requirement for the “and AI” components? Almost seems like you need a double PhD in whichever field and AI to be eligible for positions now.

[Marit Stiles @MaritStiles]

#BREAKING: Doug Ford was in such a rush to hide his phone records that his Freedom of Information changes quietly received royal assent this morning, on a Friday, with the Legislature not even sitting.

I have sent urgent letters to:

1. The Secretary of Cabinet
2. The RCMP
3. Ontario's Information and Privacy Commissioner

Each is being asked to act immediately to safeguard evidence related to the Greenbelt scandal before this government can destroy it.

As Premier, I will reverse these changes and restore transparency, trust, and faith in our democracy.

[Tyler Watt 🇨🇦 @tylerwatt]

A dark day for democracy in Ontario.

The Ford Conservatives didn’t just pass a budget - they rammed it through. Pulled it out of committee. Cut debate. Shut down scrutiny.

And buried inside? Sweeping changes to the FOI system that shield the Premier’s phone records, his office, and Ministers’ offices from the public, even wiping out requests retroactively.

This isn’t governing. It’s hiding.

And Ontarians should be furious. #onpoli

[Dr. Pierre Thibeault @frenchnerd]

Canada isn’t for sale just Doug Ford to the highest bidder.

[BBC News (World) @BBCWorld]

Ontario Premier Doug Ford criticised for $21m private jet purchase https://t.co/8GjTos0e0w

[Tyler Watt 🇨🇦 @tylerwatt]

Today is #WorldHealthDay - and it’s a reminder that health care isn’t a privilege, it’s a right.

In Ontario, too many people are still waiting for care, stuck in hallways, or going without a Nurse Practitioner or family doctor.

And behind it all are nurses and health care workers - burnt out, understaffed, but still showing up every single day for us.

We can - and must - do better. #onpoli

[Dr. Pierre Thibeault @frenchnerd]

I cannot imagine how any just nation could uphold the ability of conversion therapy programs to exist based on the technically that it’s “talk therapy” and protected as free speech.

[SCOTUS Wire @scotus_wire]

🚨 In an 8-1 vote, the Supreme Court holds that Colorado’s ban on “conversion therapy,” as applied to petitioner's talk therapy, violates the First Amendment because it constitutes viewpoint discrimination

[William Gibson @wgibson]

What if a small molecule could activate a transcription factor program in one cell type and destroy the same pathway in another? In our new preprint, we describe one such story on bifunctional molecules that toggle between transactivation and repression.