Fiset

[Jimmy O'Brien @Jomboy_]

Great at-bat from McMahon against deGrom.

He went down 0-2 swinging at two nasty changeups.

Then was able to foul a bunch off and stay alive. deGrom switches to his third pitch, curveball (hadnt been hit for an XBH hit yet this season), and McMahon turns on it.

[Talkin' Yanks @TalkinYanks]

Gorgeous pickoff from Max Fried. Yankees have picked off a runner in four straight games

(h/t @YESNetwork)

[Hudson Valley Renegades @HVRenegades]

The Ace takes the mound in HV🔥

[New York Yankees @Yankees]

Starting off with a bang 🫡

#RepBX

[New York Yankees @Yankees]

Now that's a relay 😮‍💨

[MLB @MLB]

Jake Mangum threw this baseball to a young fan ...

The moment that unfolded after will melt your heart 🥹❤️

[Fiset @fretlessbase]

I sit in that section at least 5 times every season and there's no way I'm throwing any ball I catch back. Couldn't care less about the chants to throw it if it happens to be the other team's home run ball. I've been attending baseball games most of my adult life and have never caught a ball so if I ever do, I'm keeping it.

[Fiset @fretlessbase]

So glad baseball is back!

[New York Yankees @Yankees]

Batter up.

#RepBX | @TheJudge44

[Jimmy O'Brien @Jomboy_]

Hot mics and unseen footage from Toronto's seven-game ALCS victory over the Mariners, a breakdown

[Massimo @Rainmaker1973]

A common virus may be the root cause of lupus.

Lupus has eluded medical understanding for centuries. Now, Stanford University researchers point to a surprising trigger: the Epstein-Barr virus (EBV), the ubiquitous pathogen behind mononucleosis, often called the “kissing disease.”

In a groundbreaking study, scientists linked nearly all cases of systemic lupus erythematosus (SLE)—a severe, chronic autoimmune disorder—to prior EBV infection. Although most of the 90% of adults who carry EBV experience no lasting harm, the virus appears to rewire immune cells in susceptible individuals, sparking the self-directed attacks that define lupus.

The evidence is striking: people with lupus harbor EBV-infected B cells at rates 25 times higher than healthy controls. Using cutting-edge genomic analysis, the team showed that EBV infiltrates memory B cells—typically guardians against infection—and converts them into inflammatory agents that sustain autoimmune damage.

This mechanism may also account for lupus’s unpredictable flares: EBV remains latent in the body for life, and periodic reactivation could repeatedly jolt the immune system into overdrive.

The discovery highlights why lupus strikes unevenly. Not all EBV strains are identical—some may be more aggressive—or certain immune profiles may be uniquely vulnerable to the virus’s reprogramming.

Beyond lupus, these findings could illuminate EBV’s role in other conditions, including multiple sclerosis and long COVID, potentially transforming how we approach a wide range of immune-related diseases.

["Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus." Science Translational Medicine, 2025]

[Fiset @fretlessbase]

@Rainmaker1973 Joan Jett

[Fiset @fretlessbase]

@Rainmaker1973 Honey

[Massimo @Rainmaker1973]

SpaceX Starship travel time to the planets

[🎞️ thebrainmaze]

[Fiset @fretlessbase]

TV coverage dropped the ball in that moment. Show his parents in a replay if you must but I want to see his teammates reaction on the mound and Boone's reaction as he takes the ball. Instead, by the time the cut away from his parents, the kid is half way to the dugout. Pitiful coverage.

[Tony Franklin @FretlessMonster]

Hear the full tune. (Lots of Fretless Bass!)… 🤩👏🏻

https://t.co/S8hUo6b0hw

[Fiset @fretlessbase]

@FretlessMonster Hell yeah, love it! Looking forward to hearing more! Like to see the Blue getting some love in the video...was it used for the recording as well?

[Jimmy O'Brien @Jomboy_]

The Yankees lead the league in pickoffs.

The Dodgers lead the league in getting picked off by lefty pitchers.

Max Fried is a lefty.

Max Fried leads the league in pickoffs.

[Fiset @fretlessbase]

@Jomboy_ Catcher caused both. Look how he catches them. The first one he catches vertically, letting his glove fall a foot inside. And the second one was yanked up way too much. He made both look like balls.

[The Masters @TheMasters]

On Sunday afternoon, a quiet transformation takes place. Players begin to arrive and Augusta National makes final preparations for Masters week. #themasters

[The Babylon Bee @TheBabylonBee]

Democrats Begin Spray-Painting Swastikas On Dolphins https://t.co/tKu9Y9Ilsb