longevity doctors prescribe cialis to 30 year olds with perfect dicks.
the target isn't erectile tissue.
it's the 60 000 miles of blood vessels in your body.
the mechanism is so simple.
tadalafil blocks PDE5, the enzyme that breaks down cGMP.
cGMP signals smooth muscle to relax
blood vessels dilate
blood flow increases system wide.
tadalafil has a very long half life (18 hours).
which means a low daily dose is optimal.
the list of benefits are just insane:
cognitive:
- improves cerebral blood flow (20% of cardiac output goes to brain)
- studied for vascular dementia
- reduces oxidative stress in neural tissue
- counteracts the vasoconstriction from stimulants
cardiovascular:
- lowers blood pressure
- improves endothelial function
- reduces arterial stiffness
- FDA approved for pulmonary arterial hypertension
- studied for heart failure
- addresses endothelial dysfunction (earliest sign of cardiovascular disease)
- improves insulin sensitivity and glucose metabolism
your dick working better isn't the point.
the real benefit is maintaining the most important infrastructure in your body.
i take it every morning like a multivitamin.
except instead of vitamin C
it's vitamin C-ialis.
my protocol:
- 5mg tadalafil daily
not medical advice.
L-theanine is the only legal compound that changes your brainwaves on an EEG within 40 minutes of swallowing a capsule. And the mechanism is wild.
Your brain constantly balances two opposing neurotransmitters. Glutamate fires neurons. GABA calms them. L-theanine is a structural mimic of glutamate, close enough to cross the blood-brain barrier and sit on glutamate receptors. But instead of firing the neuron, it partially blocks the signal. Your excitatory system downshifts without you feeling sedated.
That downshift cascades. GABA levels rise. Serotonin and dopamine both increase. EEG studies at Oxford showed 200mg produces measurable alpha wave activity in the 8-13 Hz range across the parietal and occipital cortex. Alpha waves are the frequency your brain produces during meditation and flow states. Most people spend years trying to access that band through breathwork. A capsule gets there in 40 minutes.
The part that makes it genuinely useful: a 2016 study gave subjects L-theanine during a multitasking stressor. The placebo group's brains shifted into high-beta stress mode. The L-theanine group maintained alpha dominance under the same conditions. Their brains stayed in calm-focus while processing the same cognitive load.
Pair it with caffeine and the synergy gets even more interesting. Caffeine alone sharpens attention but triggers tremor, anxiety, and an eventual crash. L-theanine blocks the jitter pathway without touching the alertness pathway. You get the focus of coffee without the cortisol spike. One cup of green tea contains roughly 20mg of L-theanine, which is why tea feels different from coffee at equivalent caffeine doses.
200mg daily is the dose most studies use. That bottle is 100mg capsules. Two per day. Yes, it's worth the hype. One of the few supplements where the EEG data actually matches what people report feeling.
Niacin (vitamin B3) inhibits calcification of the arteries in study.
By acting as a precursor to NAD+, B3 activates the sirtuin proteins.
Downstream, this activates autophagy, leading to the degradation of proteins that cause vascular cells to accumulate calcium.
Pretty crazy.
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