@RACARR51 While awaiting arrival of the Real @RACARR51 during the morning tea break, Dermatopathology Society of India 2025 27th Annual Meeting, Vishakhapatnam #dermpath
@RACARR51@lamcchang@SteveBillingsMD Difficult/impossible to capture exact same cells in serial recuts. A rare combination of interest/technology (spatial sequencing?)/funding might be required to definitively phenotype the cells in a decent number of cases #dermpath
@RACARR51@lamcchang@SteveBillingsMD Agree likely yes, many/most of these may not be resident intraepidermal Langerhans cells (LC1) but rather other dendritic cells recruited in (LC2, IDEC). But they are not distinguished by H&E or routinely available IHC. #dermpath