Mikio Shiba, MD, PhD, FACC

cardiologist JAPAN. I am a general cardiovascular physician.

[Mikio Shiba, MD, PhD, FACC @general_mikio]

Phenotypic Recapitulation and Correction of Desmoglein-2-deficient Cardiomyopathy using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes

https://t.co/BuHHrfCy1E

#HumanMolecularGenetics

[日本循環器学会 情報広報部会 @JCIRC_IPR]

We report endovascular findings of FMD in a young female. We perfomed PTRA and postoperative angioscopy revealed a wavy and elastic-like appearance of the intima in the renal artery.
By Mikio Shiba, MD, PhD @general_mikio
https://t.co/n5gTC35FJu
#circ_j #CardioTwitter

[Mikio Shiba, MD, PhD, FACC @general_mikio]

THANKS A LOT, Prof. Douglas L. Mann!!!
#ACC26

[日本循環器学会 情報広報部会 @JCIRC_IPR]

In 41 resected cardiac tumors, myxomas had no recurrence or tumor deaths at 12.8 year median follow up. DLBCL was right sided and fatal within 2 years. Histology predicted survival.
By Mikio Shiba @general_mikio
https://t.co/AuXTKxo5Wz
#circ_rep #CardioX

[Mikio Shiba, MD, PhD, FACC @general_mikio]

Primary effusion lymphoma-like lymphoma initially manifesting as pericardial effusion https://t.co/e31ShNkGsp

Pericardial effusion is not always idiopathic. Imaging evidence identified lymphoma, showing how imaging can redirect diagnosis and management.
#EHJCVI #CardioTwitter

[日本循環器学会 情報広報部会 @JCIRC_IPR]

This single-center study revealed that Staphylococcus spp. have surpassed Streptococcus spp. as the leading cause of infective endocarditis, with early surgery and younger age associated with better outcomes.
By Mikio Shiba
https://t.co/2xYq2SGtvC
#circ_rep #CardioX

[Mikio Shiba, MD, PhD, FACC @general_mikio]

Congenital Pericardial Agenesis Diagnosed at Advanced Age and Treated Via Minimally Invasive Repair | JACC: Case Reports https://t.co/2oObCzOUG9

Edicational movie has been published. Please check it.

[Mikio Shiba, MD, PhD, FACC @general_mikio]

A study that established the aortogenic mechanism by means of aortic endoscopy.

#openheart https://t.co/TSGWPTVKJm

[日本循環器学会 情報広報部会 @JCIRC_IPR]

This single-center study revealed that Staphylococcus spp. have surpassed Streptococcus spp. as the leading cause of infective endocarditis, with early surgery and younger age associated with better outcomes.
By Mikio Shiba
https://t.co/2xYq2SGtvC
#circ_rep #CardioX

[Mikio Shiba, MD, PhD, FACC @general_mikio]

J-STAGE Articles - Microbial Transitions in Infective Endocarditis Influence the Spectrum of Clinical Features and Functional Outcomes https://t.co/4FGy1ektQ9

[日本大学循環器内科@Nihon-U_Cardiology @NihonUCardiolo1]

Real‐World Impact of Steerable Sheaths for Paroxysmal Atrial Fibrillation Catheter Ablation: The INSIGHT Study - Okumura - Journal of Cardiovascular Electrophysiology - Wiley Online Library https://t.co/t75gbjk8O6

[日本循環器学会 情報広報部会 @JCIRC_IPR]

A 92-year-old woman underwent M-TEER for mitral regurgitation. Postoperatively, RI confirmed Takotsubo cardiomyopathy. She recovered with conservative treatment.
By Mikio Shiba @general_mikio
https://t.co/VLjppav3nu
#circ_j #CardioX

[Mikio Shiba, MD, PhD, FACC @general_mikio]

Protein C deficiency with recurrent systemic thrombosis associated wit... https://t.co/dux0SsUVW4

This is a translational study that conducted functional analysis from the gene of severe protein C deficiency.

#AHJO #ProteinC

[Mikio Shiba, MD, PhD, FACC @general_mikio]

How do you treat this case?

Aortic Thrombus Formation in the Mixing Zone of a Patient With Acute Myocarditis | JACC: Case Reports

https://t.co/PTfGv76cxP

#jacccr

[Dr. Gilbert Tang @GilbertTangMD]

Hello! Welcome to the 11/20 issue of #JACCCaseReports @JACCJournals, with mini-focus on surgery, rhythm disorder and heart failure. See our articles with links below and our 7-minute video summary of the entire issue by our AE @SyedZaidMD!
https://t.co/HEW4oV2zlw

Full PDF here.
https://t.co/YlA9RX4nzB

A 7-minute video summary on our @YouTube playlist:
https://t.co/H3kry6a3Yp

@MinnowWalsh
@DeeDeeWangMD
@hmkyale
@Justine_Turco

SURGERY
Redo Cardiac Surgery after Personalized External Aortic Root Support Operation
https://t.co/ehlyjljcJr

TAVR Explant in the Setting of a Porcelain Aorta
https://t.co/4EvEkeakg0

Extracorporeal membrane oxygenation with robotic-assisted thoracic surgery for treatment of giant mediastinal liposarcoma.
https://t.co/n30TbwXntI

Extensive Myocardial Calcification Rapidly Progressing After Orthotopic Liver Transplantation
https://t.co/zkmZWEwWPe

Rapidly worsening infective endocarditis with severe mitral stenosis
https://t.co/rI5z1hagn6

Complete Aortomitral Curtain Dehiscence Resulting in Large Pseudoaneurysm six weeks after Aortic Root Replacement
https://t.co/jV1k4jT3jp

RHYTHM DISORDERS
Three leadless pacemaker implantations in an 81-year-old woman with a history of transvenous pacemaker infection
https://t.co/ymVpPbNmF1

Short-term Synchronization of an Intracardiac Leadless Pacemaker with a Transvenous Atrial Pacemaker in a Sedentary Patient
https://t.co/XOuhYcju28

Acute Electrocardiographic Changes Coincident with Dofetilide Overdose and Acute Coronary Syndrome
https://t.co/CC2qSP1H7I

The Short RP Interval and Long PR Interval: What is the Cardiac Rhythm?
https://t.co/wCa7ePevoy

Life-saving cooperative function of a subcutaneous cardioverter-defibrillator and a pacemaker in dextrocardia with heart failure
https://t.co/v50xcKIE1R

Pericardial-esophageal fistula after combined ablation and left atrial appendage occlusion procedure for atrial fibrillation
https://t.co/yv5zxh694t

Cryoballoon Breach in Atrial Fibrillation Ablation Resulting in Massive Gas Emboli and Hemodynamic Compromise
https://t.co/fhrF9OBKWp

HEART FAILURE
Managing Left Ventricular Outflow Tract Obstruction in Combined Aortic Stenosis and Hypertrophic Cardiomyopathy
https://t.co/kXgACGmQln

BAG-3 Mutation Dilated Cardiomyopathy with Left Ventricular Noncompaction in Young Healthy Adult
https://t.co/L1kf9cogOW

Aortic Thrombus Formation in the Mixing Zone of a Patient with Acute Myocarditis
https://t.co/iTGmv7BNnk

Co-inheritance of Hypertrophic and Arrhythmogenic Cardiomyopathy Variants in a Patient with Hypertrophic Cardiomyopathy
https://t.co/StpNu5ueUS

Personalized Accelerated Physiologic Dual Rate Pacing for Cardiac Amyloidosis
https://t.co/0gcY5QTCZP

Myocardial recovery after corticosteroid therapy in rheumatic myopericarditis pediatric patient
https://t.co/7pfx4xAghC

Rheumatic Heart Disease and Endomyocardial Fibrosis: A Complex Novel Case of Heart Failure
https://t.co/HOSCtlSITl

Inferolateral fibrosis in a non-hypertrophic left ventricle
https://t.co/iFZi3oKrvZ

Unmasking Primary Carnitine Deficiency as a Mimic of Hypertrophic Cardiomyopathy
https://t.co/edw5AfMKvA

Giant Cell Myocarditis vs Cardiac Sarcoidosis: Reconsidering the Diagnosis with FDG PET Imaging
https://t.co/IJtRJlyxrj

Long-Term Outcomes of Tafamidis Treatment for Transthyretin Amyloid Cardiomyopathy in Two Patients
https://t.co/Yt1PJjQhEF

@mirvatalasnag
@BadiwalaMD
@JonChrispinMD
@KatyuciaDMacedo
@ddefariayeh
@FontanDoc
@juliendreyfus1
@sarano_maurice
@Miho_Fukui_
@theLAdoc
@Nishaki1
@ACHDocTMoe
@PamelaBMorris
@Kentso987
@colleenmstack
@m_taramasso
@SyedZaidMD

[Mikio Shiba, MD, PhD, FACC @general_mikio]

J-STAGE Articles - Aortogenic Stroke https://t.co/j77AuMFOZ9

[Mikio Shiba, MD, PhD, FACC @general_mikio]

https://t.co/gYw9R9vG6z

An interesting case, have you ever seen?

#EHJCR

[Mikio Shiba, MD, PhD, FACC @general_mikio]

https://t.co/kTK7zu97QP

Involvement of cholesterol crystals in the mechanism of aortogenic cerebral infarction: an angioscopic study

Our new triaj, CRYSTAL trial!!

#EHJ
#cardiotwitter

[Mikio Shiba, MD, PhD, FACC @general_mikio]

https://t.co/X6RUzkmbW0

#ips #BMD

[Mikio Shiba, MD, PhD, FACC @general_mikio]

https://t.co/dL6N8u9ED8

RBD is internalized through the endolysosomal pathway, which upregulates IFN‐responsive genes and promotes ISGylation in the iPSC‐CMs.

#COVID19 #ips #scientificreports

[Mikio Shiba, MD, PhD, FACC @general_mikio]

The combined histopathological assessment for tenascin-C, macrophages, and p62/ubiquitin may serve as a novel tool for
the diagnosis of DOX-CM. Doxorubicin may directly affect the expression of tenascin-C in the myocardium.

https://t.co/jIfLg6ngmb

#EHJopen