Georgeta Vaidean

MD/MPH/PhD. UNC@Chapel Hill Alumna. Research CVD Epi/Preventive Cardiology. Teach research methods. Behavior Change Counseling. Traded tenure 4 sunshine. Dancer

[Georgeta Vaidean @georgeta]

Some of the things I do.
I enjoy building new collaborations, it's how we move forward.

https://t.co/0XzlXmwhIE

[Georgeta Vaidean @georgeta]

Bucket list 4 future RCT3-->
functional co-primary EPs (love the mass but love function more), dose-response, broader population, longer FU and standardized exercise monitoring. Well-powered for multiple EPs , MICDs, will come at a cost. But, now there is hope.

[Georgeta Vaidean @georgeta]

Can we preserve muscle during GLP-1 weight loss?

EMBRAZE ph 2 RCT, most selective myostatin inhibitor, Apitegromab added to tirzepatide---> 54.9% retention of lean mass vs. placebo, w/similar total weight loss btw arms. Reassuring safety profile.

Bucket list 4 future RCT3-->

[Nature Portfolio @NaturePortfolio]

A drug called apitegromab may help to preserve lean body mass during weight loss with tirzepatide, a GLP-1 receptor agonist, according to a phase 2 clinical trial published in Nature Medicine. https://t.co/e7ItpI7ajh

[Georgeta Vaidean @georgeta]

@DrDimitrios Autonomy --> Meaning. Wish they called it lack of autonomy. More admin tasks, metricization/datafication, bureaucracy, fragmentation, speed & volume over depth & quality, keep eroding autonomy. The dominoes are falling on clinicians, researchers, educators, students, patients.

[Georgeta Vaidean @georgeta]

@MichaelMindrum Great point. Understanding where patients are coming from is as important as knowing where they want to go. Exploring their past experiences & present state & and future goals is what builds a strong therapeutic alliance, and it's the true partnering in treatment

[Georgeta Vaidean @georgeta]

4) we should not treat 150 min/wk etc as a binary success. It’s a continuum

5) MVPA and CRF relation w/CVD risk is continuous, there are no thresholds

#Exercise #CVPrev

[Georgeta Vaidean @georgeta]

Indeed, this paper is likely to create confusion. @mackinprof elegantly & patiently* articulates why MVPA 150/min/wk benefit is under-estimated, bcz it’s conditional on CRF.

While the paper has analytical strengths, the framing is a stretch & not clinically useful. Here's why:

[Stuart Phillips (he/him) @mackinprof]

https://t.co/pv5nOte9jH

[Georgeta Vaidean @georgeta]

My take:
1) yes, more than 150 min/wk is better

2) starting w/good CRF is good, keep it up; if you start w/ low CRF, work on MVPA, build CRF, big challenge & Big benefit

[Georgeta Vaidean @georgeta]

@AnastasiaSMihai @EricTopol Like w/many other issues, we do know. It's translation/implementation that we don't do. Geriatrics is still reactive not preventive. 'Healthy aging' is too often wellness' fluff while seniors are falling through the cracks, literally & figuratively. We need better systems*

[Georgeta Vaidean @georgeta]

@5_utr Agree. Tempting to see these as symptoms of a supersaturated paradigm decaying in the Kuhnian sense, the tremors of old frameworks collapsing and the noise before a radical renewal. I 'm an optimist ;-)

[Georgeta Vaidean @georgeta]

@5_utr Ah, precision is everywhere, in every field, even in precision public health. When we lack new ideas to advance a field, this mighty little word saves the day and we can write editorials and stuff in a ‘positive’ and ‘constructive’ way . Looks good on CV.

[Georgeta Vaidean @georgeta]

@drgarymcgowan Pure Dr. Mesmer stuff 🤣

[Georgeta Vaidean @georgeta]

@dranulala Yes! Taking notes, learning, drawing concept maps, brainstorming, designing new studies, visual-maps, and teaching... my med students are getting used to my handwritten notes and schematics and they seem to like those :-)

[Dr Anastasia Mihailidou FAHA FCSANZ FESC @AnastasiaSMihai]

The theme for #WorldHypertensionDay 2026 is ‘Controlling #Hypertension Together!’

A reminder for all of us to measure #BloodPressure accurately🙏

Aust Prescr 2026;49:50–4
https://t.co/oS6dBjxhBS austprescr.2026.016

[Georgeta Vaidean @georgeta]

@MichaelMindrum One Grande macchiato with butter, MCT, protein, adaptogens, peptides, omega-3s and pinch of chia seeds ! And a fork, please ;-)

[Georgeta Vaidean @georgeta]

@DrDimitrios Gaslighting is real in medicine&academia. It leads us to overidentify w/our careers while abandoning parts of ourselves. Boundaries emerge when we can no longer tolerate the loss of our unrealized potential. As human beings we are meant to flourish. Flourishing requires wholeness

[Georgeta Vaidean @georgeta]

@crblease I am so sorry to hear. He was a beacon of light and hope for the future of EBM. He will continue to be an inspiration.

[Georgeta Vaidean @georgeta]

@EvidenceOpen Hi. the matter was resolved today. Thank you! Along with my 70+ med students we are all happily using OE on all cylinders :--)

[Georgeta Vaidean @georgeta]

@EvidenceOpen Hi @EvidenceOpen any advice on what is the best way to contact your office? I tried several email accounts from your website, to no avail. I will very much appreciate a reply and a solution. Thanks a lot !