Immunostains, HNF-1beta, p53, Vimentin, p16INK4A, respectively.
My final diagnosis is clear cell carcinoma of uterine corpus. However, I understand that there may be different opinions.#pathology#Gynpath
https://t.co/yjjJndzgUm
Seminoma:
-Large dispersed cells
-Voluminous cytoplasm with peripherally located vacuoles of glycogen (blister like cells)
-Macronucleoli
-Background of lymphocytes
-Granulomatous inflammation
@roula_katerji@catherinejroe @dannyjlubinpath @vaipath@ac_pathgal@DrGeeONE
I cannot overstate more, the importance of having a significantly higher threshold for a Papillary Thyroid Carcinoma (PTC) diagnosis in the presence of Hashimoto thyroiditis (HT) on FNA. This case however, did turn out to be multifocal PTC arising in an exuberant HT.
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When "AGE" of the patient may influence your judgement. In Thyroid FNA of a 14/M, you expect to see Papillary or Medullary CA but NOT a Hurthle cell neoplasm. The resection on this showed Hurthle Cell Carcinoma (quite rare at this age).
A beautiful example of “hypervacuolization” of malignant epithelial cells in a “Papillary Thyroid Carcinoma, Cystic Variant”. Don’t disregard them as simply histiocytic.
The FORMIDABLE world of PAP Test Cytology. How high can one go on this scary-looking “Glandular” fragment? It was called “AGC-EC”. Follow-up showed an “Endocervical Polyp”. (ThinPrep)