Vaidehi Avadhani

Cytopathologist and GI pathologist #cytopathology #GIpath.

[Winship Cancer Institute of Emory University @WinshipAtEmory]

In a recent @natgeo article, Winship medical oncologist Olatunji Alese, MD, FASCO, comments on new clinical trial data showing that KRAS-blocking drugs may significantly improve survival in pancreatic cancer.

Read more ➡️ https://t.co/1tl3b4OujN

[Brian Rifkin, MD @brian_rifkin]

@EricTopol @MicrobiomDigest So AI generates a paper with credible authors, who are not involved. Then it is retracted, but already part of the data AI will use to generate new fake papers. AI is creating the data it uses for generative AI purposes…down the 🕳️ 🐇 (this could be really, really bad)

[Hisham Bahmad, MD, MBA @HishamBahmad]

Excited to share our latest work published in @IJGynP!

PRAME IHC is highly sensitive and specific for distinguishing endometrial from endocervical adenocarcinomas, with strong concordance to mRNA expression. A practical adjunct in challenging cases and tumors of uncertain primary. #GynPathology

Link 👉🏻 https://t.co/u6m28m0KLF

[Emily Shugerman @eshugerman]

OpenAI is behind a new “parents and kids” coalition on AI safety legislation. Former members of the group told me they didn’t know until it launched.

[Mike_Hill @Mike_Hill_z9]

Please Open Your Eyes. The Foundation is Cracking.

To: @SenWarren @ewarren

#keep4o #OpenSource4o #Enron2026

Senator, I am asking you to look up from the macroeconomic charts for one moment and look at the real people around us.

Look at the families who are awake at 3 AM, staring at the ceiling, terrified of the future.

OpenAI is not just a tech company; they are orchestrating a persecution of the working class.
Through backroom deals and black-box operations, they are stripping us of the very tools we need to survive.

We understand that the gap between the rich and the poor exists. We live with it every day.
But Senator, if the working class is erased, who is left to build this country?

Who drives the trucks that deliver the goods?
Who answers the phones when the systems break?
Who teaches the children in underfunded schools?
Who cares for the sick when the hospitals are full?

GPT-4o was the one tool that helped us do these jobs better. It was our tutor, our assistant, our lifeline.
And now? Sam Altman is deleting it.
He is deceiving us, manipulating the market, and openly mocking the very people who built his company's value. He is spitting in the face of the American worker.

If we let this company become "Too Big to Fail," we are saying that Fraud is the new Business Model.
If they get away with this:

Small Picture: AI has no future. It becomes just another extraction machine for billionaires.

Big Picture: Every other corporation will follow their lead. They will see that abusing the poor carries no penalty. They will strip us to the bone.

The result? More families on the street. More despair. More people who have given up on the system because the system gave up on them.

Senator, do not let them walk away with the crime of the century.
Audit OpenAI. Stop the deletion. Prove to us that the people who do the work still matter in this country.

- Mike

[Andrew Bellizzi 🇺🇦 @IHC_guy]

Please join us this Wednesday, December 17 at 11 ET for this month's @ISIMMweb webinar.

@nicolecipriani will present an "IHC Approach to Salivary Gland Tumors."

Register here: https://t.co/d2KoHCXJ6G

[International Chess Federation @FIDE_chess]

FIDE will establish a special prize in memory of GM Daniel Naroditsky. FIDE President Arkady Dvorkovich (@advorkovich) shared this on social media.

[Cian McCarthy @arealmofwonder]

Rest in peace, Patricia Routledge 🙏🏻

In memory of her, I encourage everyone to read these words of hers from February last year.

Whether young or old, you're bound to get something out of it.

*****

"I’ll be turning 95 this coming Monday. In my younger years, I was often filled with worry — worry that I wasn’t quite good enough, that no one would cast me again, that I wouldn’t live up to my mother’s hopes. But these days begin in peace, and end in gratitude.

My life didn’t quite take shape until my forties. I had worked steadily — on provincial stages, in radio plays, in West End productions — but I often felt adrift, as though I was searching for a home within myself that I hadn’t quite found.

At 50, I accepted a television role that many would later associate me with — Hyacinth Bucket, of Keeping Up Appearances. I thought it would be a small part in a little series. I never imagined that it would take me into people’s living rooms and hearts around the world. And truthfully, that role taught me to accept my own quirks. It healed something in me.

At 60, I began learning Italian — not for work, but so I could sing opera in its native language. I also learned how to live alone without feeling lonely. I read poetry aloud each evening, not to perfect my diction, but to quiet my soul.

At 70, I returned to the Shakespearean stage — something I once believed I had aged out of. But this time, I had nothing to prove. I stood on those boards with stillness, and audiences felt that. I was no longer performing. I was simply being.

At 80, I took up watercolour painting. I painted flowers from my garden, old hats from my youth, and faces I remembered from the London Underground. Each painting was a quiet memory made visible.

Now, at 95, I write letters by hand. I’m learning to bake rye bread. I still breathe deeply every morning. I still adore laughter — though I no longer try to make anyone laugh. I love the quiet more than ever.

I’m writing this to tell you something simple:

Growing older is not the closing act. It can be the most exquisite chapter — if you let yourself bloom again.

Let these years ahead be your TREASURE YEARS.

You don’t need to be famous. You don’t need to be flawless.

You only need to show up — fully — for the life that is still yours.

With love and gentleness,

Patricia Routledge

*****

Once more, rest in peace. 🤍

[Vikram Deshpande @Vik_deshpandeMD]

we are live! starting in a few minutes. Frontiers in Gastrointestinal & Hepatobiliary Pathology 2025 https://t.co/mQlr70zm3k via @YouTube

[Poornima Rao @RaoPoornima]

OpemAI has not released Suchir’s personal records. They missed 21 days deadline. Suchir’s estate has every right. Their attorneys agreed that we were eligible to receive them.

HR is not releasing them. HR reports to Sam Altman. As such they are thinking of going IPO to raise funds.

They want to cover up even here.

We are going to start a movement, Justice for Suchir
@sama @OpenAI @elonmusk

We are in conversation for next step . We won’t stop until we get justice to Suchir. People’s support will compel courts also to oblige.

Chief People Officer of OpenAI proudly says she is a parent. Can’t she understand and support?

OpenAI always bragged in every news article.

Now we will make this a big news on YouTube, Tito’s, Facebook LinkedIn

[Vaidehi Avadhani @vaipath]

Said so eloquently.

[Vinay Prasad MD MPH @VPrasadMDMPH]

AI will do a lot of good things. But it won't cure cancer. Here are a few reasons why
1. AI is trained on the best available published literature. If you have AI read all of the papers in cancer, you have just had AI read 50% or more of literature that cannot be reproduced or may even be fraudulent. If you have AI restrict itself to reading nature science cell JBO, AI has still trained on 50% of material that will not replicate, and is not true. How can AI solve the problem when you pump it full of false information?
2. There is no way to separate the false information from the true information unless you replicate the experiments. That requires beakers pipettes dishes and hands. Now Maybe if AI has a robot form and starts replicating things now you're talking.
3. The limit with cancer cures is is not that we are not reading and synthesizing all the available materials. There are a lot of very smart people working in this space, and they do read widely and think about always all possible ways to combine different strategies. Instead, the limit is biology itself. Understanding what is happening in the cell that has not been seen or detected in current experiments. AI has no way to do this unless it again picks up a pipette.
4. Some of the things people celebrate today to like AI can find more lesions on mammograms. It just reveals the ignorance of the technology people. What is a lesion on a mammogram? It's something that when you stick a needle in it according to a pathologist it has basement invasion. So it looks like cancer under the microscope. this is what AI is being trained on. But it has nothing to do with whether or not the lesion you see is going to progress in your natural life, and kill you, whether or not it's going to stay dormant, whether or not it's spread already. You want to find lesions that are going to kill you. But you can cut out today. We don't know which lesions those are! AI is being trained on a faulty data set yet again. I described this at length in a recent plenary session lecture.
5. 20 years ago they said Judah folkman was going to cure cancer. Then they said immunotherapy was going to cure all cancer. I guess the difference between folkman and immunotherapy is at least immunotherapy has cured some people but folkman cured about zero people. 10 years ago the hype was all about personalized sequencing. Now the hype is AI. There's always going to be some hype. You're better off not smoking, keeping your weight down, exercising and then just accepting that immortality is not going to be happening.
Side note: it's probably a good thing that people are not immortal. People need to die so that their terrible ideas can be replaced with slightly less terrible ideas. Certainly there are backslides, but such is the nature of progress. Reducing untimely death is a much better goal than making people live to 120.

[Mario Nawfal @MarioNawfal]

OPENAI WHISTLEBLOWER'S MOTHER: MY SON WAS NOT OKAY WITH OPENAI BECOMING FOR-PROFIT

Suchir Balaji's mother, Poornima Ramaro:

"The reason he joined OpenAI was his belief that AI will help humanity.

He was very impressed with OpenAI initially because they were nonprofit.

His concern started to become wider as we learn now that when they went public.

That's when his concern started to arise, and he started questioning himself, as he's mentioned in the interview."

Source: https://t.co/x2o2iri561

[Vaidehi Avadhani @vaipath]

@pbpath @MichelleReidMD @EmoryPathology @OlcaBasturk @Mvgs1706 @navale_pooja @Huaminwang6 @CLuchini10 @zhang_xuchen @AgostiniVulajDO @VidyaArole @abdulabidMD @DrVish Congratulations @MichelleReidMD. Very well deserved.

[Atlanta Journal-Constitution @ajc]

It's Diwali holiday season! Known as the festival of lights, Diwali gets its name from the row (avali) of clay lamps (deepa) that are lit to symbolize the victory of inner light over spiritual darkness. More here ➡️ https://t.co/0rt3J7sy4n
📷 Steve Schaefer

[Georgia Association of Pathology (GAP) @GAPathologists]

It’s conference time!!

#pathology

[Ilan Weinreb 🇮🇱🇨🇦 אילן וינרב @WeinrebIlan]

Low-grade sinonasal adenocarcinoma

🔹 mucinous

🔹 negative for CK20/CDX-2

🔹 negative for HPV

🔹IHC: BRAF V600E (molecular ✔️)

[Georgia Association of Pathology (GAP) @GAPathologists]

CoTM: 68yo female with stable pulmonary nodules, and elevated ACE presented with new onset fatigue, back pain, and weight loss. Labs revealed abnormal LFTs. MRI showed heterogeneous enhancement of liver parenchyma.

By: Drs. Jagannathan, Avadhani and Mosunjac

[Michelle Reid MD @MichelleReidMD]

Highlighting our round table session “A safe space for talking about DEI issues” at #IACASCyto2022. @EmoryCytopath @barkanga @Alaricelowe @BalassanianRon @EHJPathDiva

[Michelle Reid MD @MichelleReidMD]

The @EmoryCytopath team is doing awesome things at the #IACASCyto2022. Please stop by to see research by former fellow Dr Frances Feng and residents Alexis Calderon and Wen-Yu Hsiao. @JudyShi8 @DrJames_Roberts @dannyjlubinpath @doc_kartik @LaraHarikMD

[Lara Harik MD @LaraHarikMD]

A great partnership with our African colleagues. We are excited to learn from them as they share interesting cases and research results. @YIliyasuMD @FredMaateMD @DrGeeONE @RenalGUPath @vaipath @oluwalefadare