🧬 Is genomic profiling becoming essential—not optional—in first-line mCRPC?
Article 📰
https://t.co/5psleqFfUp
Efficacy of Olaparib Plus Abiraterone 💊 for Patients with Metastatic Castration-resistant #ProstateCancer and Single Homologous Recombination Repair Gene 🧬Mutations in PROpel
The phase 3 PROpel trial demonstrated significantly longer radiographic progression-free survival with olaparib plus abiraterone versus abiraterone alone in first-line mCRPC, with a 7.4-month improvement in median overall survival. Among patients with homologous recombination repair mutations, benefits appeared particularly pronounced in those with BRCA2 alterations, while ATM and CDK12 results also favored combination therapy.
✅ The findings strengthen the role of olaparib plus abiraterone as an important first-line treatment option.
@RayMcDermott1@NivenMehra@g_procopio_@AarmstrongDuke@OncoAlert 🚨 #LPCCC27
@Silke_Gillessen@AOmlin@ProfKHerrmann@weoncologists
🎤Our very own @mroupret & @Ric_Campi chats with @declangmurphy and @RenuEapan, hosts of @gu_onc and its spin off, European Urology Podcast.
https://t.co/K97blySTVI or listen wherever you find your podasts
Watch on You Tube: https://t.co/nKpdn5JQIP
📢Papers highlighted in this podcast include:
🩺Expanding Risk-adapted Early Detection of Prostate Cancer: A Call to Action for Men at High Risk by Maike K. Klett...Alicia K. Morgans et al
https://t.co/iA0IhdmcDO
🩺Blood and Urine Circulating Tumor DNA in Urothelial Bladder Cancer: State of the Art and Clinical Perspective by Igor Duquesne...François Audenet et al
https://t.co/4ldBN0Y0P0
🩺Cambridge kidney One-Stop Mass Investigation Clinic (CkOSMIC): A Nonrandomised Feasibility Study by Chiara Re...Grant D. Stewart et al
https://t.co/pVDXuocg1K
🩺Improved Shared Decision-making for Patients with Renal Cell Carcinoma: Results of the SDM-RCC Study by Cato C. Bresser...Paul B. van der Nat et al (for the SDM-RCC Study Group)
https://t.co/2xWwxaeERh
@uroweb@GPloussard@jteoh_hk@CaPsurvivorship@LauraMarandino@Ecastromarcos@OncoAlert@Sciencedirect
Enjoy!
Unos que extrañábamos, ARCTIC MONKEYS. Uno que nunca había venido, SAM SMITH.
Seguimos anunciando los artistas del #LollaAR 2019 ↓ https://t.co/nEKwpe89Iq
@RodolfoDonofrio seguimos vendiendo jugadores , no tenemos un suplente por puesto. Que competitivos pensamos ser? Que hacen con los ingresos? Así Se va ir Gallardo !