In the wake of the tragic shooting that claimed the life of Alex Pretti this weekend, our prayers are with his family, the citizens of Minneapolis and local, state and federal law enforcement officers serving there. The images of this incident are deeply troubling and a full and transparent investigation of this officer involved shooting must take place immediately.
The focus now should be to bring together law enforcement at every level to address the concerns in the community even while ensuring that dangerous illegal aliens are apprehended and no longer a threat to families in Minneapolis. The American people deserve to have safe streets, our laws enforced and our constitutional rights of Freedom of Speech, peaceable assembly and the right to keep and bear Arms respected and preserved all at the same time. That’s how Law and Order and Freedom work together in America.
The tragedy and chaos the country is witnessing in Minneapolis is shocking. The killing yesterday of Alex Pretti, a U.S. citizen, by ICE agents should raise serious questions within the administration about the adequacy of immigration-enforcement training and the instructions officers are given on carrying out their mission. Lawfully carrying a firearm does not justify federal agents killing an American—especially, as video footage appears to show, after the victim had been disarmed.
A comprehensive, independent investigation of the shooting must be conducted in order to rebuild trust and Congressional committees need to hold hearings and do their oversight work. ICE agents do not have carte blanche in carrying out their duties.
Prime Medicine (public company) is now valued less than what we sold Rewrite for to Intellia ($200M).
Rewrite had only raised $2M, with @CivilizationVC as sole VC - team was 5 people. Exited in under 2 years.
Prime has raised >$500M...
Timing is everything.
Cavs were favored by 3-9 points in all five games of the East semis, and the @Pacers won 4-1 (incl. 3x in Cleveland) to advance to the Eastern Conference finals for the 2nd consecutive year. This team deserves some respect!
The Pacers were down 7 with 40 seconds left before that stunning comeback to finish off the Bucks.
1 week later, the Pacers overcome a 7 point deficit with 48 seconds left to beat the Cavaliers.
Improbable. Impossible.
Recent ep of @BiotechCH has a masterclass on reframing from Josh Schimmer, who clearly sees the fed funding for academia issue differently than @JMaraganore, and effectively debates w/out disagreeing 33:40-45:45 https://t.co/8ZUSWJZ28U
Lots of data circulating on concentration of VC bets into fewer, larger biotech financings. Less discussion on implications. Is this good or bad for innovation and patients? Probably bad.
Spent two full days with institutional LPs. Can safely say that 98% of them are fed up with venture. Funds are too big (especially for new funds/spin outs), “no one does math anymore”, no liquidity. God speed to whoever is raising right now.
No dog in this fight but “No government, regardless of which party is in power, should dictate what private universities can teach, whom they can admit/hire, &which areas of study & inquiry they can pursue” doesn’t really fit w/ taking $9B in govt funding https://t.co/8xsfLGPSro
@LifeSciVC@davidycli@drrichjlaw I wish this were true, but the experience of founders raising right now is different. Biotech VCs doing direct investment are asking for clinical POC on Series A funds. That means you need to get to DC on Seed, forcing teams to choose targets and lead molecules often prematurely
@AppleHelix@LifeSciVC@endpts This is the answer. The disconnect is not sentiment vs data. There may be capital available, but not for young scientists, new founders, and good ideas from outside a venture creation fund or top academic lab that’s partnered with one. @LifeSciVC
@SaraNayeem What advice do you have for entrepreneurs who have several investors in the data room to help push to a term sheet? Seems VCs often have little incentive to move quickly and can “browse” indefinitely. How can you create urgency / drive action?
@andrewpannu Would love to see the full landscape. From 1st principles, degraders sound great. In practice, are there really that many known, disease-relevant proteins that can’t be drugged with a small molecule, peptide, or antibody?