Leny Gocheva

Science & Tech

[Cancer Discovery @CD_AACR]

Now online: Impact of vitamin D on the colon cancer immune microenvironment: results of a randomized clinical trial of preoperative vitamin D supplementation in patients with stage I-III colon cancer https://t.co/VVJBXjLYtO

[Dana-Farber News @DanaFarberNews]

"New Game-Changing Pancreatic Cancer Treatment" - Dr. Brian Wolpin of @DanaFarber sits down with Erika Edwards and NBC Nightly News to discuss a new hope for treating pancreatic cancer. Dr. Wolpin presented the study results to a standing ovation today at #ASCO26.
https://t.co/U49mIdCByB

@NBCNews @DanaFarber_Hale

[Mark Lewis, MD, FASCO @marklewismd]

Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer

Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived

#ASCO26

[NEJM @NEJM]

Presented at #ASCO26:

Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://t.co/xwLWBZYRzq

@ASCO

[Dana-Farber News @DanaFarberNews]

Vitamin D analog shuts down pancreatic cancer’s shield in clinical trial - new research from @DanaFarber and @salkinstitute published in @NatureCancer. @DanaFarber_Hale

Read more: https://t.co/26ZBT06Avj

[Dana-Farber News @DanaFarberNews]

Watch @ABCNewsLive report on a pill showing promise in treating metastatic pancreatic cancer. @DanaFarber is leading research in this area, and @BHuffmanMD details his experience enrolling patients in these clinical trials.

➡️https://t.co/jryjjaMfl6

[Dana-Farber News @DanaFarberNews]

“New treatments offer hope for deadly pancreatic cancer” - Dr. Brian Wolpin, Director of @DanaFarber_Hale, featured on @NPR's 'All Things Considered' (@npratc). @DanaFarber

➡️https://t.co/Gn7TSMmf1V

[AACR @AACR]

Altered Pancreas Function for Detection and Interception of Localized Pancreatic Cancer:
Brian M. Wolpin addressed this topic in an Opening Keynote Lecture this evening at the AACR Special Conference on Advances in Pancreatic Cancer Research.
#AACRpan25

[AACR @AACR]

#AACRpan25 cochair Andrew J. Aguirre welcomed attendees to the AACR Special Conference on Advances in Pancreatic Cancer Research this evening in Boston.
@EdnaCukierman @isteaus @LauraDeLongWood

[Leny Gocheva @gocheval]

Check out @yiwenkong1’s fantastic work at #AACR25

[Koch Institute at MIT @kochinstitute]

Visit @yiwenkong1 @LabYaffe at her poster session tomorrow 4/28 at 9am-12pm CT and learn more about how high-grade serous ovarian cancer cells become resistant to platinum-based agents and anti-microtubule drugs—the current clinical standard of care.

https://t.co/gYQvq6ai6h

[Elizabeth McKenna @ElizSMcKenna]

If you're attending the #AACR25 session on Advances in #KRAS Biology in PDAC don't miss this important @CD_AACR paper on mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer by session speaker @andrewaguirremd https://t.co/zhfPXcuP2v

[Dana-Farber News @DanaFarberNews]

Targeting resistance to RAS inhibition in pancreatic cancer: @DanaFarber's @andrewaguirremd presents in an #AACR25 session exploring advances in KRAS biology that may provide new therapeutic options for #PancreaticCancer.

➡️ https://t.co/WJqnJ07TWU

[Leny Gocheva @gocheval]

@RRomero_PhD @NatureCancer @SawyersLabMSKCC @dana_peer @HHMINEWS Congrats! Very cool work!

[Leny Gocheva @gocheval]

Another amazing @DanaFarber_Hale study presented at #AACRPan24! Check out the paper that just came out on Monday https://t.co/wqJUu5uLlU

[Marie Hasselluhn @MC_Hasselluhn]

Harsh Singh demonstrates a huge (!) study using NGS profiling on over 8,700 #PancreaticCancer patients to find predictors of chemotherapeutic response associated with basal or classical subtype. #AACRPan24

[Hale Family Center For Pancreatic Cancer Research @DanaFarber_Hale]

#AACRpan24 co-chair and @DanaFarber_Hale PI Stephanie Dougan was acknowledged this morning for her work on the AACR organizing committee

[Harmony Turk @HarmonyTurk]

If the pair of plenary sessions at #AACRPan24 on #KRAS piqued your interest, be sure to check out the In Focus article in @CR_AACR by @andrewaguirremd @BenStanger01 & @Aiims1742 on KRAS inhibition as a treatment paradigm for pancreatic cancer patients.
https://t.co/nRzMhBJOIG

[Anirban Maitra @Aiims1742]

I found these three summary slides from @cjder23 on (left) diverse mechanisms of action for KRAS inhibitors & (center, right) acquired genetic mechanisms of resistance to KRASi really useful.
#AACRPan24

[Anirban Maitra @Aiims1742]

All the KRAS inhibitor compounds @andrewaguirremd could fit on a slide!
#AACRPan24

[Leny Gocheva @gocheval]

Check out the recent @CD_AACR paper https://t.co/OVOMQBh5lo

[Leny Gocheva @gocheval]

Excited to see @andrewaguirremd kick off the #KRAS session at #aacrpan24 with an insightful
talk on the mechanisms of resistance to KRAS inhibition in #PancreaticCancer. Awesome data from @DanaFarber_Hale!