Giuliana Calia

enthusiastic about cell fate, public health, sports, and hip hop. biochem PhD student 🥽 @WeillCornellGS she/her

[ESPN FC @ESPNFC]

PURE GREATNESS.

WHAT A DAY OF WORLD CUP FOOTBALL 🏆

[Giuliana Calia @gpiacalia]

I think Ferrari had to secretly sacrifice Italy qualifying for the World Cup to get a Grand Prix win

[Nike Basketball @nikebasketball]

Sleep well, NY.

[Giuliana Calia @gpiacalia]

NYC bus drivers are laying it on the horns I love it here

[philip lewis @Phil_Lewis_]

OG Anunoby they will write stories about you

[Bryan Armen Graham @BryanAGraham]

Lauren and I went to Rikers Island to watch Game 1 of the NBA finals. https://t.co/nHuUxAB8fK

[Esfandiar Baraheni @JustEsBaraheni]

This is a 6’2 guard bullying his way to the paint, getting position and settling into a one-legged fadeaway to tie the game.

Genuinely one of the greatest scorers alive.

[Patrick Hsu @pdhsu]

people aren’t celebrating this pancreatic cancer breakthrough enough. it should be international news

[Andrew @Dub__A]

Photos of Manhattan’s Lower East Side in the 1980s by Tria Giovan

[Giuliana Calia @gpiacalia]

Twas the night before Pride x World Cup x Knicks finals month
When all through NYC,
People laid out their jerseys and flags w/ glee.
And when they drifted off to sleep,
They dreamed of joy and victory

#pridemonth #worldcup #knicks @NYCMayor

[Arjun Raj @arjunrajlab]

Can someone start a journal called “Cell Atlases” so that the rest of the journals can go back to publishing interesting things?

[Giuliana Calia @gpiacalia]

@uche_blackstock I’m curious what were the negotiations with Kenya public health groups on this? If I’m a public health official there, why would we risk bringing high risk cases in?

[Giuliana Calia @gpiacalia]

@Craig_A_Spencer Thank for continuing to share updates! I appreciate these

[Nancy Rommelmann @NancyRomm]

Where you watching the Knicks games?

[Craig Spencer MD MPH @Craig_A_Spencer]

For the @nytimes, I wrote about how cruel and horrific Ebola is, as both a provider, and as a patient.

I tried to reflect the science, and the profound sadness.

Very grateful to my editor, who pushed me to make this more personal. I usually avoid doing so. For reasons that become clear at the end of this piece.

Gift link:

https://t.co/H2BITlyawX

[Giuliana Calia @gpiacalia]

WOAH! Efficient crystallization of intermediates combined with engineered enzymes (after lots of screening). Great work hopefully leading to reduced costs of treatments in the future!

[Science Magazine @ScienceMagazine]

Researchers in Science report a kilogram-scale synthesis of enlicitide, a peptide drug for lowering low-density cholesterol that is in a Phase 3 clinical trial.

This new synthesis route leverages engineered enzymes and crystallization of key intermediates, substantially cutting down the number of reaction steps while improving yield. Learn more in a new #SciencePerspective: https://t.co/2g5nUA7d9G

[Craig Spencer MD MPH @Craig_A_Spencer]

There's a new Ebola outbreak in the DR Congo.

I'm already getting lots of questions, so let me tell you what you should know:

* This one is already big — "over 246 suspected cases and 65 deaths have been reported". This means we're just learning about this outbreak long after its already been spreading. This makes it harder to find contacts and all the cases. Most outbreaks don't get this big by the time they're over, let alone this big by the time we even recognize them.

* This one is in a really tough place — the outbreak is centered around the east of DR Congo, in a place with a lot of conflict, cross-border traffic, and instability. There may also be cases in the big city here, meaning worry for more/faster spread in an urban environment. I've worked up here, it's a tough spot to get to and work in, due to transport and conflict. There was an Ebola outbreak here in 2018-2019 that grew to over 3,000 cases.

* This is on a few borders — this outbreak is close to the Uganda and South Sudan borders. Uganda has a lot of experience with Ebola outbreaks, South Sudan less. Very possible there's already been cross-border cases, given size of the outbreak already. WHO and countries will be stepping up surveillance, but again, this is a place with a lot of conflict and instability.

* This is not your normal Ebola — most outbreaks have been of the Zaire strain of Ebola. That's the one we have vaccines and treatments for. But this outbreak appears to be due to the Bundyibugyo strain. This has caused a few outbreaks in DR Congo in the past, as well as over the border in Uganda. BUT there is no vaccine, and no treatment for this strain.

My initial reaction here is that this isn't good, at all. I'm glad Africa CDC is on it, as is WHO. But delayed recognition means this has already gotten big, at a confluence of borders with a lot of instability, and for a strain that we don't have any vaccines or treatments for.

I'll share updates as I hear them

[Giuliana Calia @gpiacalia]

A bit late to the party, but I’m excited about this work from Abigail Xie and @lydfinley lab linking mitochondrial citrate accumulation to the integrated stress response. Prompts new questions about initiating ISR!

[Cell @CellCellPress]

Now online! Citrate clearance is a major function of aconitase 2 in the canonical TCA cycle https://t.co/yZnwJRsOsM

[🧟‍♀️ @crewslover]

very happy for my personal close friend marie

[Giuliana Calia @gpiacalia]

@NaOHBartfield And yet there are so many more ways to mess up westerns ahead