Simon Grelet

Cancer Innervation and Neurobiology Lab at the Mitchell Cancer Institute
University of South Alabama
Cell-cell transfers of mitochondria - RNA biology

[Simon Grelet @GreletLab]

🎉🎉🎉 Our work on Cancer Neuroscience and Mitochondria Transfer has been selected as a runner-up for the 2025 Breakthrough of the Year by @ScienceMagazine !
I am deeply honored by this recognition and grateful to our team and collaborators!
Link: https://t.co/EFPdgrm0ur

[Mitoworld.org @mitoworld_org]

#MitochondrialTransfer as a therapy for disease moves closer to reality with @IOB_Roska's new #MitoCatch approach targeting specific cell types! Read about the @Nature paper, with author Q&A on next steps to the clinic:
#UMDF #mitochondria @mitoscientists
https://t.co/qpodtdVCuO

[Mitoworld.org @mitoworld_org]

The revolutionary #AACR26 session #MitochondrialTransfer Networks in #Cancer Progression shared revelations on central roles of #mitochondria from @GreletLab, L Gattinoni & Y Togashi. Read the groundbreaking insights! @AACR #CancerResearch #UMDF #mtDNA

https://t.co/nZNEipAchN

[Patrick Hsu @pdhsu]

Computationally designed “tree rings” for recording cellular history 🤯

I love synthetic biology inspired by mother nature’s tricks. Congrats to the authors

[Dingchang Lin @DingchangLin]

🚨 Today in @Nature, we report GEMINI—a genetically encoded intracellular memory device that writes cellular dynamics into tree-ring-like fluorescent patterns within cytoplasmic protein assemblies.[1/n]
https://t.co/eVchPCiK6f

[Simon Grelet @GreletLab]

@HindRafei @CDMRP Congrats!

[Simon Grelet @GreletLab]

See you in Phoenix! I will be speaking at the @aaas Annual Meeting 2026, where I will present our work that was selected by @ScienceMagazine Breakthroughs of 2025.
“Neurons Make a Deadly Donation to Cancer Cells,”
Friday, February 13, 2026
11:30 AM-12:30 PM MST
Phoenix, AZ

[nature @Nature]

Cancer cells use mitochondria stolen from immune cells to spread and escape detection

https://t.co/w0AGuglK30

[nature @Nature]

Nature research paper: Mitochondrial transfer from glia to neurons protects against peripheral neuropathy

https://t.co/8k0LBCxfyn

[Chris Mason @mason_lab]

“Wherever anything lives, there is, open somewhere, a register in which time is being inscribed.” - Henri Bergson (Creative Evolution, 1911). Superb start to this paper: https://t.co/Swk9raGMQX @CellCellPress "Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma"

[Simon Grelet @GreletLab]

@BrestoffLab @NatMetabolism Congratulations! This is well deserved for such an important review.

[nature @Nature]

Neurons can support cancer initiation, growth and migration and can drive therapy resistance through various mechanisms

https://t.co/FK4tl6ugeJ

[nature @Nature]

KJ Muldoon, at less than a year old, was the first known person to receive a personalised CRISPR-based genome-editing therapy

He is part of Nature’s 10, a list of people who shaped science in 2025

https://t.co/2cGBJVhwiE

[Simon Grelet @GreletLab]

@EricTopol @ScienceMagazine Thank you @EricTopol for sharing!

[Eric Topol @EricTopol]

How neurons transfer mitochondria to cancer cells to promote metastasis, a 2025 @ScienceMagazine Breakthrough runner up
https://t.co/vbraeMKiAI
https://t.co/9xyXxw3SZj

[Thomas P Seager, PhD @seagertp]

Mitochondria move thru the body.

Free mitochondria can be exported by brown fat cells into the bloodstream. From there, they transit to cells with damaged mtDNA, where they are imported and rescue mitochondrial function.

The implications for cancer therapies are profound.
https://t.co/GbHIBdSj45

[allen institute @AllenInstitute]

Holy Soma Batman!

You never know what you may find when you cruise our MICrONS Explorer, such as a blood vessel piercing the soma of a neuron!

👀 See this incredible find up close using this shortcut: https://t.co/QkoavsnhtS

[Eric Betzig @Eric_Betzig]

MOSAIC lattice light sheet xy projection over 2+ hrs in human retinal pigment epithelial cells of endoplasmic reticulum remodeling (cyan) and transport of vesicles (yellow) containing β4-galactosyltransferase....

[Eric Betzig @Eric_Betzig]

MOSAIC large field of view 3D single molecule localization microscopy of mitochondrial outer membranes and nuclear membranes in fixed U2OS cells.

[Lasker Foundation @LaskerFDN]

"I think the classic adage that the prepared mind is necessary to take advantage of the fortuitious circumstances that an individual has is absolutely right." Cell biologist Craig Thompson discusses the role of intuition in making scientific decisions in this #AskAScientist.