Miracle Drug Class of 2022
SGLT2 inhibitors
Empagliflozin, Dapagliflozin, Ertugliflozin, Canagliflozin
*Lowers mortality in CHF with systolic dysfunction
*Decreases progression of chronic kidney disease (CKD)
*Use in CKD with proteinuria, even without diabetes
Hepatorenal Syndrome
*Severe liver disease/cirrhosis in question
*Labs consistent with pre-renal numbers: BUN/creatinine ratio >20:1, Urine sodium <20
*Treat with IV albumin, octreotide and the somatostatin analogue terlipressin
*Norepinephrine is used in those in the ICU
Keys to Paget's diagnosis
*Hearing loss from compression of 8th cranial nerve
*Alkaline phosphatase and urine hydroxyproline elevated
*GGTP and calcium normal
Strongyloides enters through the skin of bare feet and go through lymphatics to the lungs and are swallowed. The skin itches, lungs with pneumonia and eosinophils and GI tract with pain and diarrhea. You finally get to use ivermectin for a legitimate benefit.
DVLA, Time Not to Drive:
1 Angioplasty = 1 week off
2 CABG = 4 weeks off
3 ACS = 4 weeks off
4 Pacemaker = 1 week off
5 ICD = 6 months
6 Catheter ablation arrhythmia= 2 days off driving
7 Aortic aneurysm > 6.5 cm = no driving
8 Heart transplant = do not drive for 6 weeks
The Supreme Court has allowed the criteria for #EWS quota, including income limit of ₹ 8 lakh, will be followed for #NEET 2021-22 admissions. | reports @kdrajagopal
https://t.co/w5RvCoalmY
A massive plume of ash billowed from Italy’s Mount Etna as it erupted on Saturday. Europe’s tallest and most active volcano has now erupted more than 50 times this year.