Gonzalo Sánchez

[Barcelonaβeta Brain Research Center @BarcelonaBeta]

Digital tools are transforming #Alzheimer research. A new systematic review from researchers at the #BBRC (@claudiaportam & @GSBenavides) explores the validation status of digital cognitive assessments for AD.

Published in @alzdemjournals

[Mariateresa Buongiorno @Mtbuongiorno75]

@MichaelOkun @JAMANeuro @CamilloHolst Furthermore, evidence in humans revealed that the use of BBB highly permeable β-blockers is associated with lower levels of amyloid-β pathology compared to less permeable β-blockers doi:10.1177/13872877241293812

[Mariateresa Buongiorno @Mtbuongiorno75]

@MichaelOkun @JAMANeuro @CamilloHolst A recent study in HD mouse model has demonstrated significantly impaired cerebrospinal fluid clearance before phenotypic onset, which worsens with disease progression. doi:10.1172/jci.insight.172286

[Mariateresa Buongiorno @Mtbuongiorno75]

@MichaelOkun @JAMANeuro @CamilloHolst The proposed mechanism involves the modulation of the glymphatic system through the reduction of norepinephrine signaling. Similar to the effect of decreased norepinephrine levels during sleep, β-adrenergic antagonists reduce glial cell volume and increase the interstitial space

[Mariateresa Buongiorno @Mtbuongiorno75]

@MichaelOkun @JAMANeuro Beaman et al. (2023) demonstrated an association between blood–brain barrier (BBB) permeable β-blockers and a lower risk of Alzheimer disease.
@CamilloHolst

[Darly Milena @darlymilena]

through the reduction of norepinephrine signaling. In the context of HD, the findings by Schultz and colleagues may also be revealing a potential role for the glymphatic system in the disease’s clinical onset and progression.

[Darly Milena @darlymilena]

Here we link the epidemiological evidence demonstrating an association between blood–brain barrier (BBB) permeable β-blockers and a lower risk of Alzheimer disease and mechanism underlying such an effect involves the modulation of the glymphatic system @MaiNedergaard @camiloholst

[Darly Milena @darlymilena]

Dear Dr @MichaelOkun I wish join a recently published commentary in @JAMANeuro explaining our point or view about "Possible mechanisms underlying the benefits of β-blocker use in Huntington disease" @GSBenavides

https://t.co/Qa8fujVJWn

[Darly Milena @darlymilena]

We are very pleased to share our latest work from our neurodegenerative disease research group "Blood-brain barrier permeable β-blockers association with Alzheimer’s disease cerebrospinal fluid biomarkers levels in non-demented individuals"

https://t.co/lPKjp13nG0

[Barcelonaβeta Brain Research Center @BarcelonaBeta]

🧠 CSF glial #biomarkers are associated with cognition in individuals at risk of Alzheimer’s disease

👉 Read the paper at @alzdemjournals: https://t.co/KXih3q4B0Q

@ncjwarmenhoven @M_SuarezCalvet @ograurivera @GSBenavides

[Barcelonaβeta Brain Research Center @BarcelonaBeta]

🧠📉 At the beginning of #AAIC24, predoc researcher David López Martos (@dlopezmartos) offered a presentation about subtle #memory decline during a research session on technological advances in neuropsychology.

🎥 We've talked to him about the main highlights of this research.

[Barcelonaβeta Brain Research Center @BarcelonaBeta]

🗞️ New paper out!

A new study led by the BBRC suggests that distinct meta-cognitive profiles can be identified in preclinical AD: hypernosognosia and anosognosia.

[Fundación Pasqual Maragall @fpmaragall]

El Dr. @GSBenavides, investigador del @BarcelonaBeta, ha rebut un ajut Miguel Servet 2022, concedit per @SaludISCIII.
La beca permetrà a l'investigador avançar en el seu estudi sobre la detecció precoç de canvis cognitius en la fase preclínica de la MA.
https://t.co/EHt4VNuNrX

[Societat Catalana de Neuropsicologia @scnps]

@hospitalclinic 🗣️@GSBenavides @fpmaragall: "La queixa subjectiva fa que les persones tinguin un rendiment cognitiu més baix"

#SCNPS2023

[Gonzalo Sánchez @GSBenavides]

@TortMerino @scnps Enhorabona Adrià! Bien merecida👏🏻👏🏻

[Fundación Pasqual Maragall @fpmaragall]

Hoy publicamos junto a @FundlaCaixa los resultados de un estudio que revela cambios cognitivos y cerebrales en personas que reúnen determinadas características vinculadas al declive cognitivo subjetivo https://t.co/W8Ib1QhHDZ

[IM Médico @IMMedicoHosp]

Un estudio de @fpmaragall identifica cambios cognitivos y cerebrales en personas con declive cognitivo @CIBERFES @CIBERBBN @FundlaCaixaCAT
https://t.co/iSCil7xX43

[Gonzalo Sánchez @GSBenavides]

#HoFaremJunts

[Gonzalo Sánchez @GSBenavides]

#HoFaremJunts

[Gonzalo Sánchez @GSBenavides]

#HoFaremJunts