Human-Microbe Systems Bioinformatics

We develop and apply #bioinformatics tools to discover #NaturalProducts in multi-omics data @Helmholtz_HIPS and @Saar_Uni | Run by group members

[Human-Microbe Systems Bioinformatics @gurevichlab]

Excited to get feedback and share our latest working paper where we employ physics-informed neural networks for the retention time prediction in gradient HPLC. Now available as a preprint on @biorxivpreprint

https://t.co/eBEHYlIElH

[Human-Microbe Systems Bioinformatics @gurevichlab]

Today @AlexKushnareva presented the poster on Hydractinia microbiome analysis (in collaboration with @CBeemelmanns)

[Aleksandra Kushnareva @AlexKushnareva]

I'm off to Würzburg for the "5th European Conference on Natural Products" today. That's a great opportunity to dive into topics like synthetic biology, #naturalproducts discovery, and chemical biology. Stay tuned 🦠🌿🧫

[Human-Microbe Systems Bioinformatics @gurevichlab]

Today @ilianolhin presented a poster on the new version of Nerpa at #gcb2024!

[Aleksandra Kushnareva @AlexKushnareva]

Today was the first day of #FYORD_Summerschool organised by @GEOMAR_de/@kielunimarine postdoctoral researchers from marine science. That's an amazing opportunity to learn more about the research projects in the area of marine biology and beyond, as well as to explore Kiel 🌊

[Human-Microbe Systems Bioinformatics @gurevichlab]

Today, we bid farewell to Shreyash Sinha, our fantastic @DAAD_Germany intern. It's been a great pleasure hosting you at @Helmholtz_HIPS & @Saar_Uni, and we wish you all the best in your future projects! We hope to continue our collaboration 🇮🇳🤝🇩🇪

[BeemelmannsLab @CBeemelmanns]

Talk of our citizens science project @microbelix_de at @Helmholtz_HIPS .. about the taxonomic, genomic, and metabolic treasure troove of Mycobacteria.

[Human-Microbe Systems Bioinformatics @gurevichlab]

@ilianolhin demonstrates his recent progress on Nerpa-MS at the annual @Helmholtz_HIPS Symposium

[Human-Microbe Systems Bioinformatics @gurevichlab]

ABC-HuMi is officially published in @NAR_Open! 📢 Explore the full paper here: https://t.co/AzF5p1yPPJ

[Human-Microbe Systems Bioinformatics @gurevichlab]

You can also explore the database here: https://t.co/cubgEicKt3

[Human-Microbe Systems Bioinformatics @gurevichlab]

Our first project featuring the whole team is now available as a preprint on @biorxivpreprint!
Introducing the ABC-HuMi database, a collection of BGCs encoding specialized metabolites in the human microbiome.
Check it out here: https://t.co/jtWkOSPFjQ

[Human-Microbe Systems Bioinformatics @gurevichlab]

You can also explore the database here: https://t.co/cubgEicKt3

[Human-Microbe Systems Bioinformatics @gurevichlab]

✨Today is a special day as @AlexKushnareva officially joins the HMSB group as a PhD student. Congratulations and best wishes for this exciting new chapter in the research journey ahead! 🧬💻

[Human-Microbe Systems Bioinformatics @gurevichlab]

A wonderful #VAAM_NP came to an end 💔. The HMSB team covered all levels of participation: a speaker, a volunteer, and an organizer 📸

[Human-Microbe Systems Bioinformatics @gurevichlab]

4️⃣StreptoAntibiotic (https://t.co/tHyUBNdaBA)
📝Insights into a biosynthetic crypticity using comparative metabologenomics unveil PTM antibiotic production secrets in Streptomyces genomes 🦠
Authors reveal PTM promoter architecture, AdpA's role, and the impact of promoter changes

[Human-Microbe Systems Bioinformatics @gurevichlab]

📅 Day 2 of the @Saar_Uni Multi-Omics Approaches to Drug Discovery seminar is here! Get ready for another batch of captivating research papers delving into the world of multi-omics! 🧪

[Human-Microbe Systems Bioinformatics @gurevichlab]

3️⃣FungiMetabologenomics (https://t.co/lDs0DqD73e)
📝Correlative metabologenomics analysis of 110 fungi unveils significant associations between #naturalproducts and their BGCs and reveals 200+ high-scoring natural product–GCF linkages for future discoveries 🍄

[Human-Microbe Systems Bioinformatics @gurevichlab]

Stay tuned for Day 2 on 14.09! 📅 More groundbreaking research and insights await as we continue our exploration of multi-omics approaches in the realm of drug discovery. 🔍 #MultiOmics #DrugDiscovery
Share your thoughts on these cutting-edge papers! 💬 #MicrobialNaturalProducts

[Human-Microbe Systems Bioinformatics @gurevichlab]

Today we participated in the first @Saar_Uni seminar on Multi-Omics Approaches to Drug Discovery! @Alexey_Gurevich chaired it and @AlexKushnareva gave a talk. Buckle up and read the highlights of five recent bioinformatics papers employing multi-omics #NaturalProducts data 🧪

[Human-Microbe Systems Bioinformatics @gurevichlab]

5⃣MetaboAnalyst 5.0 (https://t.co/if5zPL7dnt)
📝The fifth (!) edition of MetaboAnalyst, a widely-used and multi-functional web platform for metabolomics data analysis. Now with the metabolomics+transcriptomics integration! 🦠