Gus McFarlane

Biotechnologist and environmentalist | Husband and father | Researcher @nswdpi

[The CRISPR Journal @CRISPRjournal]

Editorial:
"AI and SynBio Meet CRISPR Heralding a New Genome Editing Era"
@CRISPRchef
https://t.co/oRODP3aFVZ

[Integrated DNA Technologies @idtdna]

We’re getting excited for @CSHL’s CRISPR Frontiers meeting! We'll have 4 posters on a variety of topics—see the video below to learn more. Looking forward to seeing you there: https://t.co/y2X2xAPdCQ

#CRISPR #CSHL24 #CSHL

[Be the change you want to be @AgBioWorld]

Scientists are editing out the caffeine genes using CRISPR genome engineering to develop a "natural" decaf coffee, to avoid the messy chemical process to remove the caffeine in use now. Will you drink it?
https://t.co/PuMh0YX1XH

[CRISPR News 🧬 @CRISPR_News]

NHS to offer first CRISPR gene-editing therapy for beta thalassaemia. This breakthrough could eliminate the need for lifelong blood transfusions, with promising trial results. Cost: £1.6m per patient. https://t.co/cq0R9bVd4E

[The Scientist @TheScientistLLC]

Alison Van Eenennaam (@biobeef), an animal geneticist @ucdavis, uses CRISPR technology to eliminate horns on dairy cows, create all male offspring in cattle, and generate sheep that model high blood pressure.

Read more about her endeavors here: https://t.co/SwezfnM0iE

[Gus McFarlane @gusmcfarlane]

Check out our new research note in @BioMedCentral on using CRISPResso2 with Nanopore sequencing data! Efficient, cost-effective gRNA screening! #CRISPR #Nanopore #DNA #GeneEditing https://t.co/161OkRuCj8

[National Academy of Sciences @theNASciences]

Winners of the NAS Prize in Food and Agriculture Sciences lead pioneering research in genetics, atmospheric science & CRISPR systems to bolster pollinators, safeguard crops & livestock, & enhance #foodsecurity. Nominate for the 2024 award today! https://t.co/GkAcFt7GBv #NASaward

[Frontiers - Veterinary Science @FrontVetScience]

New Research: Tackling mosaicism in gene edited livestock https://t.co/sdvKJ7RvFE #FrontiersIn #AnimalScience

[Patrick Hsu @pdhsu]

Just shared at @KeystoneSymp a new @ArcInstitute discovery of the bridge RNA recombinase mechanism: a new class of natural RNA-guided systems that retains the key property of programmability from RNAi and CRISPR while enabling large-scale genome design beyond RNA and DNA cuts

[Patrick Hsu @pdhsu]

What if we could universally recombine, insert, delete, or invert any two pieces of DNA?

In back-to-back @Nature papers, we report the discovery of bridge RNAs and 3 atomic structures of the first natural RNA-guided recombinase - a new mechanism for programmable genome design

[Genetic Literacy Project @GeneticLiteracy]

CRISPR tweaks to sugarcane leaf angles boost biomass by 18%. This breakthrough could revolutionize biofuel production and crop yields globally. @ZMEScience https://t.co/jKfCNqPv8B

[New Scientist @newscientist]

A CRISPR gene editing therapy has delivered effective, long-lasting treatment for cystic fibrosis in mice after overcoming a major hurdle that stymied previous genetic therapies. https://t.co/lYtjFHrwfk

[David R. Liu @davidrliu]

Today we report in @natBME the eePASSIGE system, which uses evolved and engineered recombinases and prime editing to integrate large gene-sized DNA cargoes into the mammalian genome in an efficient, precise, and targeted manner. (1/13)
https://t.co/xvjTwgApde

[Gus McFarlane @gusmcfarlane]

Exciting news! 🐄🐑🐖 Check out our latest publication: "Tackling Mosaicism in #GeneEdited #Livestock". We describe how #CRISPR advancements are paving the way for more efficient, sustainable breeding programs #LivestockInnovation #SustainableFarming https://t.co/rynlq8Mz6R

[Eric Topol @EricTopol]

What if there was an antibiotic that doesn't disrupt the gut microbiome?
There is now.
A discovery published @Nature today
https://t.co/njtUddaJHo @PaulHergie and colleagues @UofIllinois @justsaysinmice

[Nature Biotechnology @NatureBiotech]

Radar Therapeutics raises $13 million to design therapies using RNA sensors #NBTintheNews via @GENbio https://t.co/ZoPtqdx9oc

[Gus McFarlane @gusmcfarlane]

Research alert! 🐝 Check out our paper on #CRISPR #Cas9-targeted #nanopore sequencing of #Varroa destructor during Australia's recent outbreak. Rapid & accurate identification is crucial for response. @nswdpi https://t.co/d35yNVE0aA

[Gus McFarlane @gusmcfarlane]

Dive into the future of #biocontrol! Our paper on #CRISPR "#Gene #Drive: Past, Present & Future Roads to Vertebrate Biocontrol". Learn how this tech could revolutionise pest population management in a species-specific way. https://t.co/gU3xlqgklh
@roslininstitute
@nswdpi

[nature @Nature]

CRISPR therapy restores some vision to people with blindness https://t.co/IFtW4z0lrA

[Debojyoti Chakraborty @Debojyoti_C]

Every CRISPRDx platform has gRNA design parameters suited to the Cas protein used (Fn/enFnCas9, Cas13, Cas12, Cas14 etc.). CriSNPr designs gRNAs across different platforms (SHERLOCK, DETECTR, FELUDA, RAY etc.) and returns optimal guides for assay validation (2/n)