Fascinating talk from Dr. Jean-Christophe Marine at #AACR26 on tackling cancer cell heterogeneity and plasticity! 🧬 Instead of just enduring treatment resistance, we need to harness it. 🎯
Introducing ORIGAMI: A simple, scalable, and cost-efficient assay that monitors cell state diversity using cell Geometry scAling Metrics. 📐
Instead of relying solely on expensive multi-omics, we can now track cellular adaptation trajectories in S/V (Surface/Volume) space and strategically drive cancer cells toward a non-viable state. A massive paradigm shift in how we approach and mitigate therapy resistance! 🚀🔬
@AACR@oncodaily@OncoAlert
In the April issue, by #AACR26 Discovery Science Plenary Speaker @lab_marine: A Physical Framework to Control Cancer Cell Heterogeneity and Plasticity https://t.co/50ipaGif5X
Preprint from my postdoctoral work, in which I defined a geometric scale space integrating cell surface area and volume to redefine cancer cell states and guide therapeutic strategies.
Thanks to @lab_marine for his support, and to all co-authors!
https://t.co/rdFQ99aUxi
Great day at #EACR2024, with interesting discussions and feedbacks on my poster about a part of my postdoc work carried out in collaboration with @deepcellbio
🔬 Des chercheurs de l'@institut_curie et du @CLCCLeonBerard ont mis en évidence l’implication de la plasticité cellulaire au cours des phases précoces de la tumorigenèse mammaire et révélé son lien avec le processus de sénescence.
➡️ Lire notre actu : https://t.co/2qJlPmGTnk
Proud to share my PhD paper on how cancer cell plasticity can emerge from senescence in breast cancer! Many thanks to @PuisieuxA my thesis director, Anne-Pierre Morel, Laurie Tonon @MariaOuzounova and the entire @crcl team behind this work. https://t.co/eItN1PWQrv
💬 #MT180 QUE SONT-ILS DEVENUS ?
À l'occasion de la 10e édition du concours, (re)découvrez 🔟 candidats emblématiques des finales locales @UniversiteLyon
➡️Retrouvons @HadDeBlander (promo 2018), Bastien Marguet (promo 2022) et Emmanuel Roux (promo 2016)
👀 https://t.co/hcGSUmV4RY
https://t.co/u7xNx4eY17
My first review on cellular plasticity in relation to senescence has just been published! Many thanks to @PuisieuxA, Anne-Pierre, Maria and Aruni, my coauthors @crcl
Super happy for the collaborative paper (first for my lab!) on the intercellular propagation of #ferroptosis, an iron-dependent form of cell death!
https://t.co/tGiKabDQ8V
1/n
Japan: Intercellular signal transduction during the assembly of slime mould cells • cAMP-sensitive fluorescent probes • signal is transmitted as a spiral wave within the group • amazing • via @kotapub https://t.co/CnKHtDN8yU
📺 Vous souvenez-vous de la prestation remarquée d'Hadrien de Blander (#UnivLyon1 | @CRCL), qui avait remporté en 2018 le prix du public et le 3ème prix du jury ? La métaphore filée spéciale #Starwars avait fait sensation ! https://t.co/xCOtH4uyS5