hari jayaram

[Gavin Newsom @GavinNewsom]

You won’t hear this on Fox News:

California just released a balanced budget that wipes out the deficit this year AND next — while protecting health care and safety nets.

Meanwhile, Trump ADDED $2.4 TRILLION to the federal deficit with his “Big Beautiful Betrayal.”

Republicans ruin budgets.
Democrats balance them.

Adulting matters.

[Sen. Bernie Sanders @SenSanders]

Surprise, surprise: After months of Trump claiming Iran’s military was “decimated,” U.S. intelligence now says Iran still has 70% of its missile stockpile and most of its launch capability.

Maybe we shouldn’t let Netanyahu, a liar and a war criminal, dictate U.S. foreign policy.

[Neil Stone @DrNeilStone]

RFK Jr wants doctors to get paid to get patients off medications

That's a TERRIBLE idea

And a dangerous one

It's a conflict of interest

I get paid the same regardless of whatever I do or do not prescribe.

I do what's best for the patient.

Period.

[Alejo @ecommartinez]

🚨 ÚLTIMA HORA: El cofundador de Google DeepMind acaba de anunciar 2.100 millones de dólares para curar todas las enfermedades.

Demis Hassabis lleva años construyendo la IA que dobla proteínas, diseña moléculas y acelera el descubrimiento de medicamentos. Isomorphic Labs es su apuesta para que la IA resuelva lo que la medicina convencional no ha conseguido en décadas.

2.100 millones. Una sola misión.

[BrooklynDad_Defiant!☮️ @mmpadellan]

I'm not letting go of this.
Neither should you.

It is by far the most blatant, in your face "fuck you" to Americans that any President ever did since trump said he wouldn't take responsibility.

He should have to resign.
Anyone else would.

[Natasha Malpani 👁 @natashamalpani]

isomorphic labs just raised $2.1 billion. no human patient has been dosed yet. the first clinical trials are expected end of 2026.

zasocitinib just cleared Phase 3. the first AI-designed drug to do it.

zasocitinib was discovered by nimbus therapeutics using @schrodinger's physics-based simulation platform. the model understood molecular interactions from first principles.

it validates one specific thesis: AI works in biology when the search space is large, the functional assay is clear, and you can close the loop between model and experiment.

@IsomorphicLabs’ bet is that this same first-principles approach scales across the entire drug discovery stack. multiple therapeutic areas. multiple modalities. from structure prediction all the way to the clinic.

zasocitinib is the closest validation point this thesis has ever had. it is also a reminder that one layer working does not mean the whole stack works.

the 90% Phase 2/3 failure rate has not moved. the virtual cell is unproven. the hardest layers are still ahead.

biology does not digitise uniformly. zasocitinib is the first proof. isomorphic is the next wager.

[Governor Newsom Press Office (parody) @AwesomeNewsom]

The Art of the Steal:

1. IRS catches Trump cheating on his taxes.
2. Trump sues IRS for catching him cheating on his taxes.
3. DOJ helps Trump get $10 billion from the IRS because they caught him cheating on his taxes.
4. Americans who don't cheat on taxes will foot the bill.

[Neil Stone @DrNeilStone]

Raw milk is best with the potentially life threatening bacteria taken out of it

Which is called pasteurisation.

Odd that I have to explain this in 2026 but apparently so

[CALL TO ACTIVISM @CalltoActivism]

🚨MAJOR BREAKING: Donald Trump has arrived in China to find that President XI did NOT greet him at the airport.

MAGA is in spin mode heralding the “red carpet treatment,” but the visit is already at a rocky start.

Instead of a presidential welcome, Trump was greeted by US Ambassador to China David Perdue; Xi’s vice president, Han Zheng; China’s Ambassador to Washington Xie Feng; and Executive Vice Minister of Foreign Affairs Ma Zhaoxu.

I’m sure Trump would hate if you shared this and rubbed it in all day long.

[Republicans against Trump @RpsAgainstTrump]

Trump: “Drugs coming by sea, meaning coming by water, by ocean. A lot of people don’t know what I mean by sea. They think I mean vision. I’m talking about sea like the sea.”

The dumbest president in history

[Canada Hates Trump @AntiTrumpCanada]

Ho Lee Shit! Trump flew all the way to China to inform Chinese people that Chinese restaurants exist in America. Sweet & Sour Jesus, this fucking wonton is one egg roll short of a combo platter.

[Senator Patty Murray @PattyMurray]

I asked Director Patel to pass on my thanks for FBI's work stopping a crook who scammed Medicare out of $205 million. He obliged.

Only problem? Trump pardoned that scammer.

So which is it? Should the FBI keep uncovering fraud, or should Trump keep pardoning these crooks?

[Governor Newsom Press Office (parody) @AwesomeNewsom]

THE PRESIDENT OF THE UNITED STATES FACES A LOT OF TOUGH DECISIONS. TODAY HE HAD TO CHOOSE BETWEEN HIS BALLROOM AND HEALTHCARE FOR ITS CITIZENS. LUCKILY, WE HAVE A HUMANE PRESIDENT AND HE CHOSE THE BALLROOM. BALLROOM FIRST, ARCH SECOND, INVISIBLE PHONES THIRD, AMERICA LAST. MAGA!

[Bernie Sanders @BernieSanders]

In the United States we need hundreds of new hospitals and health clinics.

We need thousands of new child care centers.

We need millions of new units of affordable housing.

We do NOT need to spend another $500 billion on the military for endless wars.

[Alex Taylor @AlexTaylorNews]

Never forget, never forget an American VP @JDVance took time out from his country being at 𝐰𝐚𝐫 to fly over the Atlantic trying to stop Hungarians breaking free from the EU's most corrupt government

Just a few scenes of the absolute joy and freedom yesterday in Budapest👇

[Senator Mark Kelly @SenMarkKelly]

We had this conversation in a public hearing a week ago and you said it would take “years” to replenish some of these stockpiles. That’s not classified, it’s a quote from you. This war is coming at a serious cost and you and the president still haven’t explained to the American people what the goal is.

[Neil Stone @DrNeilStone]

I worked in a hospital during Covid.

Right from the start.

I can confirm that that this is nonsense.

Weapon grade horse shit.

Not remotely true and frankly libellous.

Have I been clear enough?

[Neil Stone @DrNeilStone]

OH MY GOD A COMPANY WAS TRYING TO MAKE A VACCINE FOR A DEADLY VIRUS WE'VE KNOWN ABOUT FOR 40 YEARS

MUST BE A CONSPIRACY

[Adam Schiff @SenAdamSchiff]

With summer vacations looming and monthly budgets straining, Republicans in Congress just unveiled their latest budget.

Their grand plan?

$70 billion for ICE and Border Patrol

$1 billion for Trump's gold-plated ballroom

And $0 for your bottom line.

I wish I was kidding.

[Governor Newsom Press Office (parody) @AwesomeNewsom]

The Four Horse's Asses of the Apocalypse.