Top Tweets for #BAZ1B
🥳📰🥳 Glad to see our research on the importance of #baz1b for #domestication using #zebrafish and published at @iScience_CP featured as a @QMUL news item https://t.co/y7CXdRzT05
Muy contento que @agencia_sinc se haga eco de nuestro artículo: #baz1b #domestication syndrome https://t.co/InhO9QrcfU via @agencia_sinc
Glad to see this work by @Jovitope et al. out in @iScience_CP:
https://t.co/FIl1d0q58J
They show in zebrafish, #baz1b regulates neural crest development and craniofacial features, nicely complementing our @ScienceAdvances study with @gtesta72 @polvere7
(https://t.co/Qj73shxEfQ)
NEW RESEARCH!!! We used #zebrafish to show that #baz1b influences both morphological and behavioural aspects in accordance with the #domestication syndrome hypothesis. Manuscript accepted and published online while in production at @iScience_CP
https://t.co/nBAK68EUAZ
I especially enjoyed the chapter on #selfdomestication (thanks @rcbregman for discussing our research with @gtesta72 and his group on #BAZ1B) 2/
thrilled for @TrendsGenetics highlighting the significance of our work on #selfdomestication #BAZ1B #Williamssyndrome with an insightful Spotlight by Adam Wilkins "A Molecular Investigation of Human Self-Domestication" https://t.co/Crn9hN7Knq /1
thanks to @bbcworldservice for covering our @ScienceAdvances paper https://t.co/8c7XeHBQ6s on #BAZ1B #Willamssyndrome #selfdomestication; we had a great time and you can now listen to it at https://t.co/nsLoHFvtuo minutes 10'-19'
📰 Gène #BAZ1B 🧬: une première preuve expérimentale en faveur de la thèse de l'#autodomestication de l'Homme
@ScienceAdvances
https://t.co/wGVNvpjch1
Milanチームが「#ヒトの家畜化」の遺伝子的証拠を見つけた、と主張。#Williams症候群 患者に特徴的な #BAZ1B への感受性遺伝子が、#サピエンス とネアンデルタール・デニソワで違う、と。HarvardのWrangham：「,,, one gene that is incredibly important」??
https://t.co/Xb9FhgZ4jH
📰 Gène #BAZ1B 🧬: une première preuve expérimentale en faveur de la thèse de l'#autodomestication de l'Homme
@ScienceAdvances
https://t.co/tvCRpV9Qbw
Did humans domesticate themselves? Regulatory changes in human #BAZ1B contributed to the #evolution of modern human face and friendliness, mimicking physical and behavioural changes in animal #domestication. @gtesta72 @MatteoZanella88
https://t.co/MNyFh5Xqjc @ScienceAdvances
15/ we confronted the targets of #BAZ1B with data summarizing genes affected by domestication, genes nearly fixed or selected in anatomically modern humans, and their regulatory regions @cedricboeckx @AGMAndirko @sturm_steffi @ptsgmartins @Thomas_ORourke
14/ we performed a #CRISPR tagging of endogenous copies of #BAZ1B in order to track its distribution on the genome by ChIP-seq, to identify the genes it directly regulates. @MatteoZanella88 @SebastianoTrat
12/ We found that #BAZ1B is required for neural crest induction and that neural crest migration is impaired in all genetic contexts upon #BAZ1B knock-down. @IglesiadRada @MatteoZanella88
11/ Next we performed the knock-down of #BAZ1B, taking into account several genetic backgrounds (11 individuals) spanning the full spectrum of 7q11.23 copy number (4 WBS, 3 7Dup and 3 control lines), and obtaining 3 dosages of #BAZ1B per individual @MatteoZanella88
9/ Since #BAZ1B had been described as a transcription factor and chromatin remodeller we sought to understand its contribution to the neural crest gene regulatory circuits
5/ #BAZ1B had been associated to neural crest migration in toads, and its loss to reduced facial features in mice. We thus set out first to understand its role in the formation of human facial features
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