Top Tweets for #BBSome
Dive into some #Bardet–Biedl syndrome research thanks to @IowaMed, Adipocyte-specific disruption of the #BBSome causes #metabolic and autonomic #dysfunction (Yuying Zhao et al.):
https://t.co/yRDk0nXtYJ
New paper alert: BBS1 mutations in @BardetBiedl Syndrome define two functional classes: severe variants disrupt #BBSome assembly or ciliary localization, while milder variants impair specifically TOM1L2-dependent export of ubiquitinated cargo from cilia. https://t.co/DvtGX4CqfM
How is #melanin production regulated? Study shows that on UV exposure #MC1R enters #PrimaryCilia, interacts with #BBSome & triggers signaling that stimulates #melanogenesis. The #redhead MC1R mutation affects BBSome binding, reducing melanin #PLOSBiology https://t.co/4pSnaql6j8
How is #melanin production regulated? Study shows that on UV exposure #MC1R enters #PrimaryCilia, interacts with #BBSome & triggers signaling that stimulates #melanogenesis. The #redhead MC1R mutation affects BBSome binding, reducing melanin #PLOSBiology https://t.co/4pSnaql6j8
How is #melanin production regulated? Study shows that on UV exposure #MC1R enters #PrimaryCilia, interacts with #BBSome & triggers signaling that stimulates #melanogenesis. The #redhead MC1R mutation affects BBSome binding, reducing melanin #PLOSBiology https://t.co/4pSnaqkytA
Using #Chlamydomonas, Yan-Xia Liu, Zhen-Chuan Fan et al show that ARL3 recruits the #BBSome to pass the transition zone for ciliary retrieval, providing an explanation for why Joubert syndrome phenotypically overlaps with Bardet-Biedl syndrome. https://t.co/NexAxwcDfU
#Cilia
Researchers studying the #BBSome in endothelial tissue recently teased apart some of the #metabolic effects of BBSome disruption, with a bit of help from the Promethion.
Have a look: https://t.co/LK9K8P4SgZ
#metabolism #endothelium #steatosis #ciliopathy #cilia
We are happy that we could be a tiny part of this project, which reveals a novel link between #ciliopathy and #immunity. #BBSome
https://t.co/YnUphZqx6b
Join @MaxNACHURY, PhD (@UCSF) for the #ARVO2021 Cogan Award Lecture today (11:30am EDT) to unravel Quality control of the #ciliary proteome by the #BBSome. https://t.co/5QNx8CELdN
#vision #research #ophthalmology
Join the #ARVO2021 Cogan Award Lecture on May 5 (11:30am - 12:30pm EDT) with @MaxNACHURY, PhD (@UCSF) to unravel Quality control of the #ciliary proteome by the #BBSome. https://t.co/5QNx8CELdN
#vision #research #ophthalmology
Small #GTPase #Rabl2 regulates ciliary signaling but not #ciliogenesis by licensing #BBSome-mediated membrane receptor export through the #ciliary transition zone
https://t.co/Ld9qAkMHps
Our first completely non-immunological wet project is out at @biorxivpreprint. It shows how the #BBSome, a complex mediating cargo trafficking in #cilia, is formed in cells. We are going via the @ReviewCommons pipeline again. We will keep you posted.
https://t.co/r7X0jklMuI
- Structure of the human BBSome core complex -
next @eLife publication on the #BBSome by @Intein & Alfred Wittinghofer @maxplanckpress #CryoEM
Here are both, 2 x Klink et al.
https://t.co/VqBPsw6DMv
https://t.co/EAozOMbnSj
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