Top Tweets for #BioProcessEngineering
How much of your bioreactor is actually mixing? RTD tracer studies reveal 5-30% dead volume at production scale. One pulse test, six diagnostic numbers.
https://t.co/KFRxBwDwOw
#RTD #BioprocessEngineering
🔬 $NWBO #DCVax #Eden FIGURE 3 — Motion Turns Contact into a Variable
#CellTherapy #TCellExpansion #BioprocessEngineering #Immunotherapy #Microfluidics #CellDynamics
FIGURE 3 answers the next question the system poses: how are cell–cell interactions controlled in time?
This figure introduces motion as an active design element. Cells are not left to collide randomly, nor are they held in continuous contact. Instead, the system uses directed movement to regulate when, where, and for how long cells interact.
Key features in FIGURE 3:
• Chambers are tilted and repositioned, creating predictable circulation paths.
• Cells are redistributed repeatedly, rather than settling into static clusters.
• Contact events occur in bursts, separated by periods of disengagement.
• Interaction frequency and duration are governed by mechanics, not chance.
This is a fundamental departure from static culture.
In conventional expansion, cells experience:
• continuous proximity
• prolonged receptor engagement
• accumulating local stress
Those conditions make interaction monotonic. Once contact begins, it does not stop.
FIGURE 3 replaces monotonic contact with patterned engagement.
By forcing cells to move through the chamber, the system:
• limits how long any two cells remain engaged
• prevents signal saturation
• avoids prolonged receptor occupancy
• introduces recovery windows between interactions
This matters because immune signaling is time-dependent, not just concentration-dependent. Cells interpret duration and frequency of engagement as information. Continuous engagement conveys a very different message than repeated, transient contact.
Another important point: the motion in FIGURE 3 is gentle and repeatable. There is no indication of turbulent mixing or harsh agitation. The goal is not to maximize collisions. It is to shape exposure.
FIGURE 3 shows that the inventors are not relying on cytokine dose or receptor density alone to control behavior. They are using physical timing as a regulatory lever.
This turns mechanics into biology.
When movement controls contact, and contact controls signaling, then motion becomes a way to govern cell fate without adding more stimulus.
FIGURE 3 does not yet tell us how fast cells expand or how many are produced. It establishes the rules of engagement that expansion will follow.
If FIGURE 2 defined the chamber as the control surface,
FIGURE 3 defines motion as the control knob.
Together, they show that expansion in this system is designed to be patterned by physics, not driven by brute-force stimulation.
💥 New Special Issue open for submission!
🔗 https://t.co/FbX2426gDq
#syntheticbiology #metabolicengineering
#enzymeengineering #bioproducts #biomanufacturing #bioprocessengineering #chemicalengineering
We are hiring Assistant Professors (Lecturer Level B or Senior Lecturer Level C) at The University of Queensland in Australia in #Bioengineering, #BioprocessEngineering, #Biotechnology, and #BiomedicalEngineering
Apply here: https://t.co/5NrP9l5xGL
#TenureTrack #FacultyJobs
@DARPA If you have deep bioprocess expertise and a builder’s mindset, we want you.
👉 Apply here: https://t.co/eBbHVJotRh
#biomanufacturing #scaleup #bioprocessengineering #DARPA #SynBio #biotechinnovation
📢 New #specialissue: “Advances in Sustainable Environmental Biotechnology and #BioprocessEngineering for Pollution Control in Different Agroecosystems” is now open for submissions in #AgricultureMdpi!
📝 Guest Editors: Dr. Marcela Levio-Raiman and Prof. Dr. Maria Cristina Diez
How do you prepare students for the job market? #BioprocessEngineering Check out our latest publication. @Chem_Eng_J @UQ_News @UQ_EAIT @DalilaIannotta @mkmasud_bd @JustinCooperWh1
https://t.co/lvKiz5oh5R
Watch the latest episode of "NewIn“ with Michael Zavrel, Professor of #BioprocessEngineering at our Straubing campus, where he talks about his goal to transform a #fossilbased economy into a #bioeconomy: https://t.co/8mzSq4Mk1c
#sustainability #biofuels
🎥@ProLehre
***Behind Springer Chemistry***
👩🔬Working in the field of bioprocess and sustainable production processes?
Discover the journal Bioprocess and Biosystems Engineering journal at
https://t.co/s4U1iUiQN4
#BehindSpringerChemistry #SpringerChemistry #BioprocessEngineering
Simple IMO4 Making Formula at Home | Ngụy Đình Kỳ
#VinSinhIMO4 #FermentationFormula #MenVinSinh #Biotechnology #YeastCulture #FermentationProcess #MicrobialGrowth #IMO4Microbiology #BiochemicalEngineering #YeastFermentation #VinSinhHoc #BioprocessEngineering #BioreactorDesign
As an #alumni, I happy to take part in the upcoming graduation ceremony of the departments of #Bioengineering, #Bioinformatics, #BiotechnologicalQM & #BioprocessEngineering @FHCampusWien and to give this year's #speech on the topic of "Digitalisation in the Natural Sciences". 🤩
@johncumbers Great to see the impressive number of companies involved in your dynamic! The big challenge we face in #biomanufacturing is being able to scale up and combine #SyntheticBiology and #BioprocessEngineering whatever the field of application
An exciting visit @FH_Aachen offered the Brazilian innovators from #EnergInno many compelling insights. They were invited to visit the NOWUM laboratory and the labs for #BioprocessEngineering and #DownstreamProcessing. More about this #GermanRDTour 👉https://t.co/q1o1MUK9Wj
Prof. Nils Tippkötter, @FH_Aachen, is presenting the #BioprocessEngineering and #DownstreamProcessing labs to the Brazilian delegates of the #GermanRDTour of #EnergInno Brazil. Follow the link to get more information about the tour 👉 https://t.co/KamVybm3E3
Here is Prof. Nils Tippkötter, @FH_Aachen, and a representative of the German #EnergInno tandem 'Bio2H2'. He shares insights into his research areas, #BioprocessEngineering and #DownstreamProcessing, with the Brazilian counterparts of the EnergInno campaign led by @Fraunhofer_en.
Our Center's new bioprocess design removes the most potent fermentation inhibitors during pretreatment — and recovering these valuable chemicals adds to the profitability of CABBI's #biorefinery.
📰 Paper in @sciencedirect's Journal of Cleaner Production: https://t.co/ab2bCVl1ya
Very happy of our latest publication from @LeoRiosLab improving the regioselectivity and activity of plant P450s in S. cerevisiae combining #Synbio #biocatalysis #bioprocessengineering approaches.
Great work from @SimplyBehnaz and colleagues! @MBB_Ncl https://t.co/U8KNOAUOTF
Co-localizing pathways using RNA scaffolds @ACSSynBio #synbio #bioprocessengineering from Tian Wei Tan et al. 💪🏼
“Metabolic Engineering Mevalonate Pathway Mediated by RNA Scaffolds for Mevalonate and Isoprene Production in Escherichia coli”
https://t.co/pqdjdEpqsG
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