Top Tweets for #BoniniLab
Excited to see our hard work in print! 🪰🧠 Congratulations @chinabyrns and everyone on the team!
#BoniniLab #Drosophila #Senescence #BrainAging
https://t.co/IQQ9KKM3rQ
Our ataxin-2 study from #boninilab is out now! We show that the toxicity of ataxin-2 repeat expansions is influenced by trinucleotide repeat composition using Drosophila models @LeeanneMcgurk @UofPenn
Excited to share our ataxin-2 study. A combined effort from #boninilab that wouldn’t have been possible without @olivia_rifai!
Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence https://t.co/CblYVWu4Lc
Excited to share our ataxin-2 study. A combined effort from #boninilab that wouldn’t have been possible without @olivia_rifai!
Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence https://t.co/CblYVWu4Lc
A cause of dementia is head and brain injuries. Read about how brain injury can be induced and monitored in the tiny fruit fly here in Nature protocols. #boninilab
https://t.co/2wl2RtmpgA
Our review on poly(ADP-ribose) in neurological disease is now available to access for free. @olivia_rifai #ALS #dementia #PARP #boninilab
Poly(ADP-ribosylation) in age-related neurological disease https://t.co/CHKsqjJ2Cl
Check out Janani Saikumar's work on traumatic brain injury in the fruit fly #boninilab
Dynamic neural and glial responses of a head-specific model for traumatic brain injury in Drosophila https://t.co/oisT4FJoOT
Check out some of the research @LeeanneMcgurk and I did on TDP-43 @Penn, accepted manuscript now in @J_Cell_Sci 😊 #als #dementia #boninilab #tdp43 #parp #tnks
Excited to share our publication on Tankyrase and TDP-43. It was a really fun project made possible by the talented @olivia_rifai when we were in the #Boninilab.
TDP-43 a protein central to amyotrophic lateral sclerosis is destabilized by Tankyrase-1/2 https://t.co/gcMHya8Dr8
Excited to share our publication on Tankyrase and TDP-43. It was a really fun project made possible by the talented @olivia_rifai when we were in the #Boninilab.
TDP-43 a protein central to amyotrophic lateral sclerosis is destabilized by Tankyrase-1/2 https://t.co/gcMHya8Dr8
This a great summary of our latest work about poly(ADP-ribose) in ALS and dementia by @ResOutreach #boninilab a collaboration with @ShorterLab @TNRLab @vivivandeerlin
Drs Nancy Bonini and Leeanne McGurk are using fruit flies, mammalian systems and in vitro protein preparations to investigate promising new molecules that could help lead to new treatments for amyotrophic lateral sclerosis (ALS).
https://t.co/MDf3zqbfGb
Could motor neuron toxicity in #C9orf72 #ALS be reduced by targeting RAN translation? A new study @NatureNeuro opens up the possibility https://t.co/CF7osHM05J #PAF1 #BoniniLab via @ShorterLab
Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated #FTD https://t.co/8kSzqozzze
eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS @LDGoodman #boninilab https://t.co/MSkEdEpTl7
#ICYMI That's right. #StressGranules may actually protect neurons against #ALS #MND by helping to prevent TDP-43 from aggregating - at least early in the disease https://t.co/MfbKOXNkiU @LeeanneMcgurk @MolecularCell #BoniniLab @ShorterLab
And now we have trilogy in the regulation of TDP-43 by poly(ADP-ribose). In collaboration @ShorterLab @LinGuo18, Ed Gomes and of course Nancy Bonini! https://t.co/L2FoKYYuOt
#boninilab
Chia-Yu Chung's awesome paper is out #boninilab, "Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity" https://t.co/HAOhyHh57v
Jason Kennerdell’s paper is out #boninilab MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging https://t.co/zuzouxmGCB
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