Top Tweets for #CDK6
Geoffrey Shapiro, MD, PhD (@GShapiroMDPhD) presenting his research on reversing #CDK6 expression to circumvent CDK4/6 inhibitor resistance at the
@df_hcc Breast Cancer Program Research Retreat. #CDK #BreastCancer
So what is a CDK4/6 Inhibitor? Dr. Sherry Shen breaks it down for us.
#ASCO2023 #MBCResearch #CDK4 #CDK6
CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation
🔗https://t.co/Pw9e4931rM
#CDK6 #CellCycle
#BCSM #CaxTx
@cbblab1 @MartinFloorP
Our paper that discusses the role of #microRNA inhibition in #PDAC is now online #PancreaticCancer #CDK4 #CDK6 @proteomics #noncodingRNAs #CancerResearch
YX-2-107 is a selective #CDK6 #PROTAC (IC50= 4.4 nM) degrader. #CDK6 exhibits growth-promoting functions in hematologic #malignancies. YX-2-107 can inhibit the development of Ph+ ALL (acute lymphoblastic leukemia) in rats.
https://t.co/AXuHRtSFqJ
At #ESMO22 an interim analysis investigating a #CDK4, #CDK6 inhibitor + NSAI recently led to an increase in median overall survival by over 12 months in patients with HR+, HER2- early #breastcancer
Full interview with Dr Matthew Goetz @mpgoetz here: https://t.co/187aQUaJFX
At #ESMO22 an interim analysis investigating a #CDK4, #CDK6 inhibitor + NSAI recently led to an increase in median overall survival by over 12 months in patients with HR+, HER2- early #breastcancer
Full interview with Dr Matthew Goetz @mpgoetz here: https://t.co/187aQUaJFX
Happy to share my 1st paper from my PhD, now available on @biorxivpreprint. We analysed global human kinase-substrate relationships & developed a new method to study #CDK6 activity.
Special thanks to @haraldjanovjak @rtsabapathy @ARMI_Labs @EMBLAustralia @FlindersHmri. See 🧵1/6
CDK6 activity in a recurring convergent kinase network motif https://t.co/nEsb3bGYvn #bioRxiv
#ASCO ER+ #breastcancer may develop resistant ESR1 #translocations . Research @Baylor shows promise for #RET and #CDK4/#CDK6 inhibition to control. Can we keep #chemo at bay longer?
#AACR2022 peeps & co, read up on argeting #CDK4 and #CDK6 in cancer in this @NatureRevCancer Review by @shomgoel, Bergholz & Zhao: https://t.co/fXiYS1TpXW
@natrescancer @PeterMacRes @UniMelbMDHS
🔓 #OpenAccess
CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal
➡️ https://t.co/s0hMElXfVN
@UoDMedicine @UoDLifeSciences @GREDundee @UNCResearch
#CDK4 #CDK6 #BreastCancer #Palbociclib #ReplicationStress
#Trilaciclib is a #CDK4 and #CDK6 #inhibitor with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively. #drugdiscovery. https://t.co/0BypYteFmf
CDK6 is a therapeutic target in myelofibrosis https://t.co/ZLUcyvxDyD
Happy to share our new article. We identify #CDK6 as a therapeutic target in Myelofibrosis #Palbociclib
@CR_AACR
#Blood #Cancer #CancerResearch
@uvahealthnews
@AACR
Der Arzneimittelentwicklung Flügel verleihen: Forschungsteam der #VetmeduniVienna/@PharmaVetmeduni arbeitet an vielversprechendem Projekt zur Entwicklung eines neuartigen Wirkstoffs gegen Krebserkrankungen!
#CDK6 #KHANI #wings4innovation #w4i
👉 https://t.co/PJGkQFcgwM
Today's #ConnectScience at 12EST:
@shomgoel (@PeterMacCC & @PeterMacRes), "Targeting #CDK4 & #CDK6 in Cancer: New Insights and Opportunities"
Next on Thurs 3/25:
Junjie Chen, PhD (@MDAndersonNews)
For zoom link:
https://t.co/HiM0kmyVAe
#CancerCenter #Cancer
@theNCI
⭐️ONLINE NOW @NatureCancer : "Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders" - a fantastic work by @Poulikakos_Lab on the impact of thermostable CDK6 in #TherapyResistance
Find it here:
https://t.co/8Xzx3SdRgt
https://t.co/Ahwrednh7J
Cyclin Pathway Genomic Alterations Across 190,247 Solid Tumors: Leveraging Large‐Scale Data to Inform Therapeutic Directions
#CellCycle #CDK4 #CDK6 #PrecisionOncology #MolecularGenetics #CancerGenome #TargetedTherapy
https://t.co/cPPfb0KhpN
Read the new #openaccess paper
by @sofie14165808, Karoline Kollmann & Veronika Sexl:
｜The role of CDK6 in cancer ｜
➡️https://t.co/699WqL9pAD
Part of IJC’s Invited Review series
#cancer #CDK4 #CDK6
@VetmeduniVienna
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