Top Tweets for #CMRGUIDE

25 days ago

#CMRGUIDE at #ESCCongress Should myocardial SCAR—not just EF—help determine who gets a primary-prevention ICD? Patients with: ➡️ LVEF 36–50% ➡️ Ischemic or nonischemic cardiomyopathy ➡️ Scar/fibrosis on CMR Randomized 353 pt, impacted by COVID, 82% Men ⏱️6.3 y ICD vs implantable loop recorder Primary Endpoint= SCD or hemodynamically significant ventricular arrhythmia 🌟RESULTS: Primary: SCD or hemodynamically significant ventricular arrhythmia ➡️ HR 0.76 (95% CI 0.37–1.58), P=.47 ❌ Sudden cardiac death alone: ➡️ HR 0.26 (0.07–0.95), P=.04 All-cause mortality: ➡️ HR 0.91 (0.49–1.71), P=.78 🫀 CMR-guided ICD implantation did not reduce the primary composite endpoint. The reduction in SCD is intriguing, but as a secondary endpoint in a negative trial it should be interpreted cautiously. CMR scar alone does not yet appear sufficient to expand ICD indications beyond current EF-based criteria. 📄 https://t.co/0gx5m5ygiN @JAMA_current #WhyCMR #CardioTwitter #EPeeps #HeartFailure

DrMarthaGulati's tweet photo. #CMRGUIDE at #ESCCongress

Should myocardial SCAR—not just EF—help determine who gets a primary-prevention ICD?

Patients with:
➡️ LVEF 36–50%
➡️ Ischemic or nonischemic cardiomyopathy
➡️ Scar/fibrosis on CMR

Randomized 353 pt, impacted by COVID, 82% Men
⏱️6.3 y
ICD vs implantable loop recorder

Primary Endpoint= SCD or hemodynamically significant ventricular arrhythmia

🌟RESULTS:
Primary: SCD or hemodynamically significant ventricular arrhythmia
➡️ HR 0.76 (95% CI 0.37–1.58), P=.47 ❌
Sudden cardiac death alone:
➡️ HR 0.26 (0.07–0.95), P=.04
All-cause mortality:
➡️ HR 0.91 (0.49–1.71), P=.78

🫀 CMR-guided ICD implantation did not reduce the primary composite endpoint. The reduction in SCD is intriguing, but as a secondary endpoint in a negative trial it should be interpreted cautiously.

CMR scar alone does not yet appear sufficient to expand ICD indications beyond current EF-based criteria.

📄 https://t.co/0gx5m5ygiN @JAMA_current

#WhyCMR #CardioTwitter #EPeeps #HeartFailure

Edward J Schloss MD

@EJSMD

over 6 years ago

@bogdienache @NickCurzen @drjohnm Interesting that #CMRGuide will only look at EF 36-50% patients. Lots more enthusiasm about increasing than decreasing the ICD pool, I guess.

Prof Joseph Selvanayagam DPhil FESC

@josephselvacmr

over 8 years ago

Further confirmation that we need better tools for risk stratification in these patients #WhyCMR #CMRGuide @Dr_JYounger @GaetanoNucifora @chiarabd @drashnisbet @Becho2106 @Suchi_Grover @SAHMRI_Heart @Flinders https://t.co/HCd69CQhxB

Dr. Alex M. Benevides🇧🇷 @alxbenevides

over 8 years ago

#CMRguide App: I deeply recommend! Have u ever known?@rahatheart1 @EM_RESUS @SamRRazaMD @iamritu @rosencher @AnastasiaSMihai @DrKristieLeong @lipiddoc @DrKhouryCDC @sjauhar @DrJennHaythe @DrShawnGroth @DrEricLevi @drmlb @Dr_Beale_ @SABOURETCardio @CardioIAN #MR #CardioTwitter

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