Top Tweets for #CanCOLD
Parabéns a @FredLAFernandes e a #SuzanaTanni pelo editorial no @EuroRespSoc Journal, sobre o estudo #CanCOLD, ratificando que viver em bairros socioeconomicamente desfavorecidos acelera o declínio da função pulmonar e piora sintomas respiratórios!
🔗 https://t.co/2gBZahHGuH
🔥🔥"Physiological Characterization of Preserved Ratio Impaired Spirometry in the CanCOLD Study"
📄 Study Overview:
This study explores Preserved Ratio Impaired Spirometry (#PRISm) in the #CanCOLD cohort, analyzing its impact on exertional dyspnea and exercise intolerance. It targets an often-overlooked population that shows preserved FEV1/FVC ratios but faces severe exercise limitations.
💪 Strengths:
✅A large, well-defined cohort (#CanCOLD study) ensures robust results.
✅Clinically relevant outcomes measured (dyspnea scale, 6-minute walk test).
✅Comprehensive statistical adjustment for age, sex, smoking status, and comorbidities.
⚠️ Limitations:
🧩 Observational design limits causal conclusions.
📊 Potential selection bias from cohort characteristics. The study population is older, which may limit broader generalization.
🔬 Key Findings:
1️⃣ PRISm patients exhibit significantly ⬆️ exertional dyspnea than those with normal spirometry.
2️⃣ Exercise capacity (measured by 6-minute walk test) was ⬇️ in PRISm patients.
3️⃣ Despite a preserved FEV1/FVC ratio, PRISm patients showed reduced lung volumes and diffusion capacity.
📊 Implication: PRISm may be a distinct phenotype of respiratory impairment that clinicians should recognize early.
🚨 Conclusions and Future Implications:
Clinicians should screen for dyspnea and exercise intolerance in patients with #PRISm even when they don't meet #COPD criteria.
Further research is needed to understand the progression of PRISm and develop targeted interventions.
📢 PRISm isn't just "normal"—this study challenges us to rethink respiratory care beyond classic obstruction criteria.
🔗 #EvidenceBasedMedicine #RespiratoryHealth #ClinicalResearch #PRISm #CanCOLD #COPD
⏩https://t.co/Uf8RqkzNlh
Excited to see this published online!
Physiological Characterization of Preserved Ratio Impaired Spirometry in the CanCOLD Study: Implications for Exertional Dyspnea and Exercise Intolerance @ATSBlueEditor #CanCOLD #dyspnea #CPET
https://t.co/Mu6dIXA9Fi
It’s World Chronic Obstructive Pulmonary Disease Day #worldCOPDday Visit the new Canadian Cohort Obstructive Lung Disease (#CanCOLD) to learn about one the most important studies to answer Qns related to COPD in the world: https://t.co/S2mQ1lSebH @GOLD_COPD @CTS_SCT @CIHR_ICRH
Lessons from the North: CanCOLD, Exercise and COPD. OPEN ACCESS @QueensRIU @queensutime @QueensuDOM @CanRespirResNet #CanCOLD https://t.co/hw2sJ9vtk8
#Ambient #Air #Pollution and #Dysanapsis: Associations with #Lung #Function and #COPD in the #CanCOLD Study #AJRCCM @ATSBlueEditor https://t.co/TbPrBVoO8a
I cannot wait to share the final copy-edited version when it is available. I would like to give a sincere thanks to all the co-authors on the paper, along with the rest of the #CanCOLD team that made (& continue to make) this fabulous 9-centre study possible!
This study shows that high blood eosinophil count is significantly related to rapid FEV1 decline in all people, independent of well-established risk factors such as smoking and age, and may be related to undetected airway abnormalities https://t.co/UfCOrclZyj
Identification and definition of #asthma- #COPD overlap: The #CanCOLD study. #Pulmonary #Lung https://t.co/bXMpVOoVf7
I think I just found @longjohnindex a hardy west coast bureau chief.
#cancold #longjohnindex https://t.co/5IpmlMM3f7
My friends in Victoria are posting about braving -2 degrees and a few inches of snow. I can't wait to go back home and make fun of them.
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