Top Tweets for #ComplementActivation
🩸🚀Today’s clinical questions!
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#PNH #ParoxysmalNocturnalHemoglobinuria #Eculizumab #Ravulizumab #C5Inhibition #ComplementSystem #BreakthroughHemolysis #PKBreakthrough #Pregnancy #ComplementActivation #DrugClearance #PlasmaVolume #MaternalHealth #ThrombosisRisk #Hematology #HemeOnc #ClinicalHematology #MedicalEducation #MedEd #HEMEHUB
Novel insights into #APS extend beyond #Thrombosis to NETosis, #ComplementActivation and #MicrobiomeDysbiosis. The 2023 ACR/EULAR criteria refine diagnosis. Adjunctive therapies such as HCQ, rituximab and eculizumab show therapeutic potential: https://t.co/a5GX6RjkSx #MedTwitter
"It could make someone useless for a year+" ~ @StatisticUrban . Yep! 13 years + of #MEcfs disability for me stemming from #malaria and residual #Hemozoin. Elevated #ComplementC7 #ComplementActivation #TLR3 #MGUS
If you've never had malaria, it's awful. It infected over 1 million per year, caused widespread anaemia, miscarriage, and childhood death. The disease could last for months, with multiple recurrences, and led to chronic undernourishment
It could make someone useless for a year+
The connection between #SARSCoV2 and #PNH is significant, with infection potentially unmasking or #exacerbating PNH through #complementActivation, and vaccination, particularly mRNA types, posing a risk of hemolytic flares.
https://t.co/jm5GcRq8wU
Study highlights the role of #ComplementActivation in #APS, linking elevated C3a, C4a, C5a, & C5b-9 levels to more severe cases, including recurrent #thrombosis & CAPS. Findings suggest complement inhibitors like eculizumab may offer new treatment options: https://t.co/XDdxdsHNRk
Study explores #ComplementActivation in #AntiphospholipidSyndrome, aiming to clarify its role in thrombotic recurrences and disease severity. Mechanistic studies seek markers and evaluate complement inhibition: https://t.co/NyMDuTRvD1
New #openaccess laboratory study. Does #dexmedetomidine help prevent cognitive decline induced by sleep loss via #complement? #sleepdeprivation #complementactivation #anaesthesia #criticalcare
https://t.co/T4b6tuYCTW
Interesting article from Pfizer
🔬 Researchers investigate complement activation by AAV9 gene therapy vectors in human serum samples
🔍Scientist used NAb, TAb and complement assays to understand AAV9 complement activation.
#AAV #GeneTherapy #ComplementActivation #Immunology 1/2
Why do so many pancreas transplants fail due to thrombi? This study shows increased thromboinflammation and association with #complementactivation in pancreas transplanted patients (especially those who only get a pancreas and not a kidney) https://t.co/N1LBFhs6pl
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