Top Tweets for #ComplementPathway
π©ΈFacts about PNH & Breakthrough Hemolysis:
PIGA mutation leads to loss of CD55/CD59, driving complement-mediated intravascular hemolysis, thrombosis, and nitric oxide depletion symptoms.
#Hematology #PNH #ComplementPathway #ComplementSystem #RareDiseases #MedEd #HematologyEducation #ClinicalEducation #Pathophysiology #Immunology #Autoimmunity #Hemolysis #IntravascularHemolysis #ParoxysmalNocturnalHemoglobinuria #Thrombosis #BoneMarrowFailure #Dysphagia #HEMEHUB
aHUS Treatment Options:
#aHUS #Hematology #Complement #ThromboticMicroangiopathy #EndothelialInjury #C3Convertase #RareDiseases #KidneyDisease #Microangiopathy #HematologyExperts #ComplementPathway #ClinicalHematology #Nephrology @aHUSUKvoice @ThrombosisCan @iuis_online @EuropeanTHA @hemolyticanemia @isth
@HTRStoday @HTRSFellows @ASNKidney @Kidney_Research @RareDiseases @rarediseasesnet
@rarediseaseuk
#ICYMI from Brandon L. Garcia @EastCarolina: Structural basis for classical #complementpathway inhibition by #LymeDisease spirochetes | #ReadTheJI #immunology #structuralimmunology π https://t.co/MkOmgDKWZk
#Sutimlimab targets #C1s, the first step in the classical #ComplementPathway, and is the first agent specifically approved to treat #CAD
Thrombotic microangiopathies, including #aHUS, are #rarediseases involving the #complementpathway of proteins. We get diagnostic results ASAP to the #hematologist, #nephrologist, or #clinicaltrial sponsor, which means better outcomes.
If you are developing therapeutics that target the #complementpathway, we hope to see you at the annual summit in Boston, sponsored by @MachaonDx! Early bird registration ends today.
https://t.co/1E1xwT9N4I
Activation of #C3convertase is critical for complement activation, leading to the production of key effector molecules and initiation of later events in the #complementpathway. Learn more about C3 and #geographicatrophy at https://t.co/ILX6cOBLKZ.
Exploration of the #complementpathway is broadening our understanding of #retinal diease and potential therapies for #GA. π©βπ¬ποΈVisit this interactive diagram to reaquaint yourself. https://t.co/ybIsBnpOK4
The #complementpathway is activated by three pathways. Learn about each path and the role of various factors in the cascade through this interactive diagram from @RetinaToday. https://t.co/ILX6cOBLKZ #AMD
Could targeting complement pathway activation at the initiating molecule of the classical pathway be the long-awaited answer to developing a treatment for GA secondary to AMD? #sponsored #complementpathway https://t.co/EOsaqweHaF
We're off to #Denver for the AMLI's 30th Annual Meeting! Visit us to learn about our #ComplementPathway & #TherapeuticDrugMonitoring assays!
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