Top Tweets for #ComplementSystem
Two drug candidates may bind a complement target similarly yet differ substantially in how well they suppress complement activity. Why one assay rarely tells them apart: https://t.co/scuoc6xQoe #ComplementSystem #DrugDevelopment
🩸Facts about PNH & Breakthrough Hemolysis:
PIGA mutation leads to loss of CD55/CD59, driving complement-mediated intravascular hemolysis, thrombosis, and nitric oxide depletion symptoms.
#Hematology #PNH #ComplementPathway #ComplementSystem #RareDiseases #MedEd #HematologyEducation #ClinicalEducation #Pathophysiology #Immunology #Autoimmunity #Hemolysis #IntravascularHemolysis #ParoxysmalNocturnalHemoglobinuria #Thrombosis #BoneMarrowFailure #Dysphagia #HEMEHUB
New insights into complement activation! Cryo-EM structures from Prof. Junyu Xiao’s lab reveal how C4b2a and C3bBb engage C3 in classical/lectin & alternative pathways, respectively (2.6-3.1 Å). Key to disease & drug development!https://t.co/sEfwZrJwpD
#ComplementSystem #CryoEM #Immunology #PKUResearch
New study shows deleting FHR1 reduces atherosclerosis, inflammation, and plaque formation in mice—revealing a novel immune-lipid axis in cardiovascular disease.
#Atherosclerosis #CardioScience #Immunology #ComplementSystem #TranslationalResearch https://t.co/LCKaJpkkcy
Ruah Alyamany (@Ruah_Mahmoud) on Complement Mediated HUS
https://t.co/45rzMkL4ab
#BleedingDisorders #ComplementSystem #Health #Hematology #Hemostasis #HemostasisNews #HemostasisToday #HUS #Medicine #MedEd #MedX
ICYMI: The complement system in intestinal inflammation and cancer
As part of JCI’s Review series on complement biology and therapeutics, @carstenkriegPhD & Silvia Guglietta @gugliettalab @MedUnivSC highlight the #ComplementSystem in the GI tract under homeostasis, inflammation, and during tumor development, progression, and treatment: https://t.co/Kks9gOOMhP
Congratulations to Dr. John Lee and Prof. Simon J. Clark recipients of the 2025 Svar Complement Excellence Award, presented at the International Complement Workshop in Brisbane
#ComplementSystem #ICW2025 #ComplementingLifeScience #ComplementExcellenceAward
⚡️Complement in IgA Nephropathy: New drugs are reshaping care!
🎯 From C3 to C5 & beyond—Pegcetacoplan, Iptacopan, Ravulizumab & more 🧬💊
🔗 https://t.co/aMRVgH3hP3
@NDTsocial
#IgAN #Nephrology #ComplementSystem #CKD
The complement system plays a key role in NMOSD pathophysiology and targeting it has opened new doors in treatment.
Today’s session, presented by Alexion, highlights the science driving innovation in rare neuroimmunology. #ComplementSystem #NMOSD #NMA2025
Complement C3 rise in aging impairs memory, brain health.
Discover more at the 10th Edition: Aging & Gerontology
📅 Sept 8–10, 2025 | 📍San Francisco, CA, USA
Website: https://t.co/OmIv0hjVhN
#AgingResearch #Neuroinflammation #Alzheimers #CognitiveDecline #ComplementSystem
5/
This was an amazing collaboration with the @lab_wiener and @RouvinskiLab - thank you! 🙌
Graphical abstract below ⬇️
#SARSCoV2 #COVID19 #Virology #CellReports #ComplementSystem #Immunology
🧬 New from the CureGN Study:
📄 Clinical Significance of Immune Deposits and Complement System Activation in FSGS. @ASNKidney @CureGn @slunephrons @virginieroyal @KristaLentine 🙏☺️🙏
#Nephrology #FSGS #CureGN #GlomerularDisease #ComplementSystem
C5b9uPR is emerging as a significant biomarker for FSGS progression, reflecting the complex interplay between complement activation, inflammation, and kidney injury.
https://t.co/vjfNWp8NJv
#ASNKidney360
Thrilled to share that our latest review is officially published in Seminars in Immunology!
#cancer #complementsystem
Beyond the Norm: The emerging interplay of complement system and extra... https://t.co/lrBLxGUIkc
Interesting insight:
C3 glomerulopathy: a kidney disease mediated by alternative pathway deregulation.
#C3G #nephrology #kidney #complementsystem
https://t.co/AGPcjhWnGp
Todays #ComplementinLifeScience explores Iptacopan's journey: the first oral complement Factor B inhibitor. From its first-in-human study to FDA approval for PNH in 2023. #ComplementSystem https://t.co/iUGiaapLyW
Reminder! Apply for the Svar Life Science Complement Excellence Award by June 1st at 00:00 CET. Two grants of 20,000 EUR await! Nominate yourself or a peer today. Visit https://t.co/FmkEJn5OM9 for details. #ComplementBiology #LifeScience #ComplementSystem
If you’d like to learn more about the novel #complementsystem inhibitors, developed @IOCBPrague meet us at our booth @BioVaria today & tomorrow or contact #IOCBTech via https://t.co/eo5araZmv9
#TechTransfer #innovation #BioTech #BioVaria2024
From our partner @IOCBPrague, Hagen Sülzen will now be talking about PX, a selective, alternative pathway inhibitor for #treatment of complement dysregulation diseases. The matching poster is I2. #BioVaria #inflammation #ImmuneResponse
Hagen Sülzen @IOCBPrague is presenting a novel way of regulating the #complementsystem to treat diseases caused by a miss-function of the #alternativepathway of the human Immunsystem
#techtransfer #BioVaria2024 #BioTech #Innovation
Ketamine's rapid impact on depression linked to immune system pathways 🧬💉🧠 https://t.co/M25U7TlJtp #Ketamine #Depression #MentalHealth #ComplementSystem #Neuroimmunology #Antidepressants #MolecularPsychiatry @NaturePortfolio
💧 🐭 Filtration and tubular handling of EWE-hC3Nb1, a complement inhibitor nanobody, in wild type mice and a mouse model of proteinuric kidney disease
👉 https://t.co/JeHID2aqDv
@WeyerKathrin @gregers_rom
#ProteinuricKidneyDisease #Immunology
#ComplementSystem #KidneyTwitter
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