#Developability - Twitter Hashtag

about 1 month ago

We're looking forward to attending #PEGSBoston next week 👈😀👉 Come and visit us at booth 713, and attend our #Developability Predictions talk on Monday, May 11, 10:15 #PEGSummit #Biologics #AntibodyModeling #ProteinEngineering #AntibodyTherapeutics #DrugDiscovery

CCG_MOE's tweet photo. We're looking forward to attending #PEGSBoston next week 👈😀👉 Come and visit us at booth 713, and attend our #Developability Predictions talk on Monday, May 11, 10:15 #PEGSummit #Biologics #AntibodyModeling #ProteinEngineering #AntibodyTherapeutics #DrugDiscovery https://t.co/sdxS41YzXi

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Goose Farmer @oneseo80

about 1 year ago

#Antibody #Developability (1/2) NotebookLM을 가장 유용하게 활용하는 부분이 복잡한 논문을 일반인의 눈높이에서도 읽을 수 있다는 점이다. 물론 이를 통해 전문가 수준의 지식과 인사이트를 얻는 건 불가능하지만, 대략적으로나마 surface-level 지식은 얻을 수 있다. 며칠전 @Ginkgo 블로그에 올라온 항체 개발가능성(antibody developability)에 대한 논문을 NotebookLM으로 돌려보았다. 일반인 눈높이에서 핵심 요지를 뽑아본다면: a. 항체가 잘 작동하기 위해서는 정밀한 표적 결합력뿐만 아니라, 안정성, 점도, 응집성 등 다양한 개발 가능성(developability)을 만족해야 하는데, b. 이러한 개발가능성이 높은 항체를 AI가 잘 선별하기 위해서는 대량의 고품질 실험 데이터를 가지고 AI를 트레이닝시켜야 한다. c. Ginkgo 는 자동화 플랫폼을 만들어 일주일당 수천개 항체를 실험했고, 그 결과 생산된 대량의 데이터로 AI 모델을 훈련했더니, AI가 항체를 선별하는 정확도가 크게 증가하였다는 얘기이다. → 즉 투입되는 데이터의 양이 많을 수록 AI 성능도 좋아진다는 것을 증명했다.

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Prof Andrew C.R. Martin @PrfAndrewMartin

over 1 year ago

Prof Andrew C.R. Martin I'm pleased to say our paper on using protein language models to help with #antibody #developability assessment has just been published in mAbs. First author, talented (now ex-) PhD student, James Sweet-Jones. https://t.co/1zC8fsLswu

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Anne Ljungars @AnneLjungars

over 3 years ago

Check our review on #developability of #biologics!

Monica L. Fernández-Quintero @moonii1020

over 3 years ago

Developing #biologics, such as #antibodies, comes with multiple challenges. Check out our latest review on #developability of biologics published in @mAbs/@AntibodySociety today, providing an overview of current strategies and advances in the field. https://t.co/CFeTDtIN57

moonii1020's tweet photo. Developing #biologics, such as #antibodies, comes with multiple challenges. Check out our latest review on #developability of biologics published in @mAbs/@AntibodySociety today, providing an overview of current strategies and advances in the field. https://t.co/CFeTDtIN57 https://t.co/Y0a4MlRd3I

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Monica L. Fernández-Quintero @moonii1020

over 3 years ago

We review in silico strategies, including machine learning and molecular dynamics simulations, cell-based assays, and in vivo methods to assess #developability, #immunogenicity, and #pharmacokinetics on a large number of drug candidates.

moonii1020's tweet photo. We review in silico strategies, including machine learning and molecular dynamics simulations, cell-based assays, and in vivo methods to assess #developability, #immunogenicity, and #pharmacokinetics on a large number of drug candidates. https://t.co/iX2jLfzdU7

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Monica L. Fernández-Quintero @moonii1020

over 3 years ago

Antibodies can be derived from different sources and in addition to efficacy, #developability is a key attribute for success. Herein, we describe #biochemical and #invitroassays, which can be used to remove #drugcandidates with bad properties early in the discovery process.

moonii1020's tweet photo. Antibodies can be derived from different sources and in addition to efficacy, #developability is a key attribute for success. Herein, we describe #biochemical and #invitroassays, which can be used to remove #drugcandidates with bad properties early in the discovery process. https://t.co/ESUx2LqTtZ

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Monica L. Fernández-Quintero @moonii1020

over 3 years ago

Developing #biologics, such as #antibodies, comes with multiple challenges. Check out our latest review on #developability of biologics published in @mAbs/@AntibodySociety today, providing an overview of current strategies and advances in the field. https://t.co/CFeTDtIN57

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Timothy Jenkins @TimothyPJenkins

over 3 years ago

Thrilled to share our latest publication! Check out this comprehensive review on #Developability of #Biologics in #mAbs from @TheAbSociety. This collaboration included 16 expert authors, 4 universities, and 4 companies. Read it here: https://t.co/QNJriqMIF8

TimothyPJenkins's tweet photo. Thrilled to share our latest publication! Check out this comprehensive review on #Developability of #Biologics in #mAbs from @TheAbSociety. This collaboration included 16 expert authors, 4 universities, and 4 companies. Read it here: https://t.co/QNJriqMIF8 https://t.co/eGa5hReQqP

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Monica L. Fernández-Quintero @moonii1020

over 3 years ago

Proud to see our new review on #developability of biologics published in @mAbs/@AntibodySociety today, providing an overview of current strategies and advances in the field. Amazing collaboration between academia and industry!

Andreas Laustsen @AndreasLaustsen

over 3 years ago

Excited to announce the publication of this new, comprehensive review on #Developability of #Biologics in #mAbs from @TheAbSociety: https://t.co/utovnvy5iB This excellent cross-border collaboration involved 4 different universities, 4 different companies and 16 expert authors.

AndreasLaustsen's tweet photo. Excited to announce the publication of this new, comprehensive review on #Developability of #Biologics in #mAbs from @TheAbSociety: https://t.co/utovnvy5iB
This excellent cross-border collaboration involved 4 different universities, 4 different companies and 16 expert authors. https://t.co/FfeOvptPZV

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Andreas Laustsen @AndreasLaustsen

over 3 years ago

Excited to announce the publication of this new, comprehensive review on #Developability of #Biologics in #mAbs from @TheAbSociety: https://t.co/utovnvy5iB This excellent cross-border collaboration involved 4 different universities, 4 different companies and 16 expert authors.

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Rapid Novor Inc @rapidnovor

over 3 years ago

The #Developability Navigator #InSilico tool (DENIS) evaluates antibody Fvs using #moleculardynamics simulations to identify candidates that possess similar #molecularproperties to #marketstage, #antibody #therapeutics. Read the @ACSPublications paper: https://t.co/V6nszai3fj.

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Life Science Newswire @LifeSciNewswire

over 4 years ago

@enpicom introduces a powerful liability prediction solution to de-risk antibody development https://t.co/Bh518EH0uE #bioinformatics #software #antibodies #developability

LifeSciNewswire's tweet photo. @enpicom introduces a powerful liability prediction solution to de-risk antibody development https://t.co/Bh518EH0uE #bioinformatics #software #antibodies #developability https://t.co/24X13DcS1L

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Muirhead PS @muirhead_ps

almost 5 years ago

Primary 4 played games to show their knowledge of rounding numbers. Article 31 #righttoplay Article 29 #developability

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Genedata @Genedata

over 5 years ago

Discover how #Genedata supports Sanofi in assessing the #developability of novel drug candidates to deliver best-in-class #biotherapeutics. Download the Case Study here! https://t.co/yLLOYtquar #GenedataExpressionist #MassSpectrometry #DigitalizingBiopharma

Genedata's tweet photo. Discover how #Genedata supports Sanofi in assessing the #developability of novel drug candidates to deliver best-in-class #biotherapeutics. Download the Case Study here! https://t.co/yLLOYtquar
#GenedataExpressionist #MassSpectrometry #DigitalizingBiopharma https://t.co/IoyeFjpCrC

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CCG_MOE @CCG_MOE

over 5 years ago

[Online Conference] @chi_peptalk Look forward to our talk: #Developability 𝗔𝘀𝘀𝗲𝘀𝘀𝗺𝗲𝗻𝘁 𝗮𝗻𝗱 𝗣𝗿𝗼𝗽𝗲𝗿𝘁𝘆 𝗣𝗿𝗲𝗱𝗶𝗰𝘁𝗶𝗼𝗻 𝗯𝘆 𝗽𝗛-𝗗𝗲𝗽𝗲𝗻𝗱𝗲𝗻𝘁 𝗖𝗼𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗼𝗻𝗮𝗹... Wed, Jan 20 @ 10:05 Pacific Time👈😃More @ https://t.co/Xh1RnQ2Jwq #Biologics

CCG_MOE's tweet photo. [Online Conference] @chi_peptalk Look forward to our talk: #Developability 𝗔𝘀𝘀𝗲𝘀𝘀𝗺𝗲𝗻𝘁 𝗮𝗻𝗱 𝗣𝗿𝗼𝗽𝗲𝗿𝘁𝘆 𝗣𝗿𝗲𝗱𝗶𝗰𝘁𝗶𝗼𝗻 𝗯𝘆 𝗽𝗛-𝗗𝗲𝗽𝗲𝗻𝗱𝗲𝗻𝘁 𝗖𝗼𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗼𝗻𝗮𝗹... Wed, Jan 20 @ 10:05 Pacific Time👈😃More @ https://t.co/Xh1RnQ2Jwq #Biologics https://t.co/mm0UpGXvDl

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Ian Kerman @neodenium

over 5 years ago

Today is the last day to see my #poster on using #machinelearning to predict #antibody #developability at #ANTIBODYENG. If you aren't attending the conference, my presentation here is also available here: https://t.co/lsth4bLZDs. #LifeSciences

neodenium's tweet photo. Today is the last day to see my #poster on using
#machinelearning to predict #antibody #developability at #ANTIBODYENG. If you aren't attending the conference, my presentation here is also available here: https://t.co/lsth4bLZDs. #LifeSciences https://t.co/1Q3yT8Pbsc

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AISCongress @congress_ais

over 5 years ago

#8AIS2020 – Discover the Talks from @PierreFabre , @SymphogenIT @sanofi @MedinCell @CEAParisSaclay @Servier on Complex Biologics #CMC & #Developability Track at 8th #Antibody #Industrial Symposium – Nov 23-24 – now #virtual - More info: https://t.co/dX0FejkWbG

congress_ais's tweet photo. #8AIS2020 – Discover the Talks from @PierreFabre , @SymphogenIT @sanofi @MedinCell @CEAParisSaclay @Servier on Complex Biologics #CMC & #Developability Track at 8th #Antibody #Industrial Symposium – Nov 23-24 – now #virtual - More info: https://t.co/dX0FejkWbG https://t.co/yN9CuRr0dP

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iBET @ibetportugal

over 5 years ago

📘Early assessment of drug stability is associated with higher success rates while reducing overall project cost and timelines. Learn how to potentiate early-stage #developability studies of biopharmaceuticals 👉https://t.co/zUixElvACw @Novartis

ibetportugal's tweet photo. 📘Early assessment of drug stability is associated with higher success rates while reducing overall project cost and timelines.
Learn how to potentiate early-stage #developability studies of biopharmaceuticals 👉https://t.co/zUixElvACw

@Novartis https://t.co/ldOwB1xLzI

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CCG_MOE @CCG_MOE

over 6 years ago

[𝗪𝗢𝗥𝗞𝗦𝗛𝗢𝗣𝗦] Had a great workshop last week in Basel! 😍 #SmallMolecule session in the morning, #Biologics in the afternoon 😀 More about upcoming workshops at https://t.co/WIjjM4zten #MedChem #CompChem #VirtualScreening #DrugDiscovery #Proteins #Antibody #Developability