Top Tweets for #Digitoxin
Digitoxina reduce muertes o ingreso al hospital por empeoramiento de la insuficiencia cardíaca en pac c/insuficiencia cardíaca y fracción de eyección reducida q reciben terapia médica según guías #digitoxin #death #heartfailure https://t.co/gd3tWAE00A https://t.co/gd3tWAE00A
🫀DIGIT-HF subgroup analysis presented at #HeartFailure26 by Prof. Udo Bavendiek, explored the efficacy & safety of #digitoxin in #HFrEF according to #AFib status:
📍HFrEF➕AF represented a clinically higher-risk phenotype with more comorbidities & symptoms
📍Digitoxin ⬇️ the composite of all-cause death or first HF hospitalization irrespective of AF status
📍In AF subgroups: ARR 10.5%, NNT 10 for the primary endpoints
📍The apparent benefit seemed more pronounced in patients with AF, mainly driven by reductions in all-cause mortality
@escardio @HFA_President @MarcoMetra @JBauersachsMD

#Digitoxin in #HFrEF: what did DIGIT-HF really show?
Join the upcoming #HFA_ESC Journal Club for a comprehensive review of digitoxin pharmacology, DIGIT-HF design & findings, & what’s the implication for clinical practice & contemporary #HF management
🗓️When: 27 January 26 | 18:00-19:00 CET
📚Faculty: Prof #UdoBavendiek, Prof #PetervanderMeer, Dr @Jolie_Bruno_, & Dr @corneliacrm
Register now: https://t.co/4xEHE1MjGk
@escardio @MarcoMetra @jozinetm
#HFAyoung @JBauersachsMD
#HeartFailure

🫀 HFA Journal Club is back!
Join us for a sharp discussion on digitoxin in heart failure (HFrEF) and what the evidence really says DIGIT HF trial
📅 27 Jan | 💻 Online (free for HFA members)
👉 https://t.co/hcm6TXfkPP
#HFA #HFAJournalClub #HFAYoung
@HFA_President @escardio
👵👴 #AHA2025: Subanalyse aus DIGIT HF zeigt, dass #Digitoxin auch bei älteren HFrEF-Patienten mit hoher Komorbidität wirken könnte.
📊 Prof. @JBauersachsMD stellte Daten vor.
🎙️Prof. Aßmus kommentiert klinische Implikationen.
➡️ https://t.co/yCS3Y07uNy
#Herzmedizinde #DGK
Discussing the #DIGIT-HF Trial : #Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction
Insightful exchange with @ARakisheva on the #DIGIT-HF Trial and its implications for modern #HFrEF therapy
#HeartFailure
@mmamas1973 @mirvatalasnag @HFA_President @ShelleyZieroth @GianluSava @GiuseppeGalati_ @biljana_parapid
🔥 Nicht verpassen am Freitag in der ACC-ESC Congress-News Session: #DIGIT_HF‼️
✅ #Digitoxin bei #HFrEF
@DjawidHashemi @papathanasiou_ @SamiraSoltaniMD @DavidDuncker @DrV_Mann @TRassafMD @HenrikeHillmann

📌 DIGIT-HF Study
👉 Revival of #digitoxin in 👥 with #HFrEF
📣 Digitoxin 💊 -compared to placebo- ⬇️ combined risk of total #death 💀 or HF #hospitalization 🏥❗️
#HeartFailure #CardioTwitter #MedTwitter @drjohnm @DrMarthaGulati @JagSinghMD @GiuseppeGalati_ @SeguraCardio @Hragy

#DigitHF demonstrated an 18% reduction in death & HHF with digitoxin vs placebo on top of GDMT in only 1212 patients w advanced HFrEF (36 mo)!
Efficacy driven by 📉 in ☠️ + 🏥
What is #digitoxin & how does the evidence fit into current Tx? Listen @radcliffeCARDIO
#ESCCongress

🎙️NEW #ESCCongress 2025 🔥 Hot Line Discussion 🌟 Prof Udo Bavendiek joins host Dr @hvanspall to explore findings from the DIGIT-HF trial.
📽️Watch here 👉 https://t.co/XjpjH35s1g
📊Digitoxin reduced the risk of all-cause mortality and hospitalisation in patients with worsening heart failure.
#ESCCongress2025 #ESC2025 #CardioEd
#DIGIT-HF Studie weißt Überlebensvorteil von #Digitoxin bei der #HFrEF zusätzlich zur bisherigen maximalen Standardtherapie nach!
Niedrige Dosierung von 0,07mg empfohlen.
Tot gesagte leben länger. Rein medikamentös betrachtet 😁😎
https://t.co/IrgZZZMuG2
🚀 DIGIT-HF trial
Treatment with #digitoxin led to a lower risk of death or hospitalization for heart failure among patients with HFrEF 💊
@escardio ♥️
#ESCCongress #CVPharma #HeartDrugs #Pharmacotherapy #HeartFailure #HFUpdate

DIGIT-HF (Hotline 1) for #digitoxin
心不全の治療って,昔は利尿剤とジギタリスしかなかったんですよね。
今回ESCでジギトキシンがHFrEFの予後改善効果が示されたのは驚きです。選択肢が拡がって武器が増えるのは歓迎です。以前にtwとしたジギタリスの花ですが、綺麗を超えてきました。#ESCCongress

🔥 long awaited data on digitoxin💊 in chronic #HFrEF
✔️ significant reduction in death or first hospital admission for worsening heart failure
✔️ treatment with digitoxin was safe
https://t.co/W2gTnAsdBq
➡️ more data on digoxin to follow next year #DECISIONtri @CardiologyUmcg

🔥Fresh from the HotLine 1 #ESCCongress #WCCardio‼️
DIGIT-HF: #Digitoxin use in #HFrEF by #UdoBavendiek:
📍N:1212 of patients with chronic HFrEF, NYHA II + LVEF ≤30% OR NYHA III-IV + LVEF ≤40% on GDMT >= 6months
📍Digitoxin ⬇️risk of composite of all-cause death or worsening HF receiving a well-implemented GDMT
📍ARR 4.6%, NNT 22
📍Consistent across subgroups (incl. ARNI & SGLT2i)
📍Safe, no signal of excess harm
➡️ Supports use of digitoxin in HFrEF on top of modern therapy
@escardio @JBauersachsMD @jozinetm

#ESCcongress 2025 #Abstract
#digitoxin works!! Even in patients with optimal contemporary medical therapy
https://t.co/JcrVHIJiOY
@TCTMD @TCTConference @news_hart @Ortega_Paz @sjorge4 @sbrugaletta @NievesGonzalo1 @CRT_meeting @GTCardFellows @PCRonline

@HFA_President @escardio @MarcoMetra @jozinetm @slumberbell @AmrAbdin10 @WilfriedMullens @corneliacrm @HanCardiomd @SotiriaLiori @_antocannata @h_arfsten @GTersalvi @hvanspall And clearly do not miss Hotline 1, Friday 11-12.00‼️
➡️ Main results of the #DIGIT_HF trial investigating #Digitoxin vs Placebo in #HFrEF🔥
@SamiraSoltaniMD @ShelleyZieroth @escardio #ESCCongress #heartfailure @slumberbell @GiuseppeGalati_ @EJHFEiC
#HeartFailure2025
🔥Hotline starts 10.45 with
➡️ #DIGIT_HF baseline characteristics‼️
Simultaneous publication in #EJHF 🔥
✅main results reg #Digitoxin in #HFrEF to be presented at ➡️ @escardio in Madrid
@slumberbell @markcpetrie20
@EJHFEiC

Kein alter (Finger-)Hut: Comeback für #Digitoxin? 🌿 Kann es bei systolischer Herzinsuffizienz (HFrEF) Leben verlängern? Das untersucht die DIGIT-HF-Studie. Prof. @JBauersachsMD dazu im Video-Interview:
📺https://t.co/pjma9fWJhu
#Herzmedizin #DGK
Hot results from #DIGIT_HF published Clin Res Cardiol‼️
https://t.co/lJFsjnIQTg
Simple and safe #Digitoxin dosing in #HeartFailure
➡️ starting dose 0.05 mg for most patients
@DGK_org @YoungDgk @GiuseppeGalati_ @GMCRosano @DavidDuncker @Kardiophil @KardiologieHH @TRassafMD

Hot of the press in #EHJ ‼️
➡️ our viewpoint article on
Digitalis in heart failure: declining use and ongoing outcome trials
@ehj_ed @ESC_Journals #cardiotwitter @ShelleyZieroth @TRassafMD @GiuseppeGalati_ https://t.co/L6zaYe8uJA
Da es fortdauernde Lieferprobleme für Digitoxin gibt, veröffentlicht die DGK eine Handlungsempfehlung für den Einsatz alternativer Medikamente.
Hier unsere aktuelle Pressemeldung:
https://t.co/NODs3KxWVR
@JBauersachsMD #Digitoxin #Lieferengpass
#Digitoxin 0,07mg von ratiopharm ist wohl noch verfügbar…
➡️ generell überprüfen, ob Indikation zu Digitalis Therapie (noch) indiziert ist.
➡️ für #DIGIT_HF Studie besteht kein Problem, die Studienmedikation ist bereits produziert‼️
Great to be in Belgrade with Udo Bavendiek and Marija Zdravkovic and all #DIGIT_HF investigators from 🇷🇸 Serbia‼️
We will clarify whether #Digitoxin in addition to standard #HFrEF drug treatment will improve outcomes.
@rudolf_deboer @GiuseppeGalati_ @Herzstiftung @DGK_org

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