Top Tweets for #EBNA1
https://t.co/mBU5DCdaWS
"High-level Epstein-Barr virus (EBV)-derived Epstein-Barr nuclear antigen 1 (#EBNA1) peptide antibody titers may be an MS-specific biomarker that could the improve differential diagnosis."
"...#EBNA1 positivity in [#MultipleSclerosis] ranged from about 92% to 93% depending on the age group. In #MOGAD, it was around 61%. In #NMOSD, about 89%. In other neurological diseases, rates were in the 70% to 80% range, and in controls, about 78%."
🧬 Could #EBV antibodies help clarify #MS diagnoses?
Tanuja Chitnis, MD discusses research showing EBNA-1 antibodies are present in ~98–99% of patients with MS
Read more here: https://t.co/4hM1V3pyqE
#MultipleSclerosis #Neurology #EpsteinBarrVirus #Q&A
"Significantly elevated #EBNA1 IgG levels were detected in serum& CSF of [indivs w/ RR #MultipleSclerosis]... CSF EBNA1 IgG & indices based on specific CSF EBNA1 IgG assoc with CSF albumin or serum EBNA1 IgG assoc w/ total serum IgG" had⬆️sensitivities. https://t.co/fkRO0qiU55
![IJMSCtweets's tweet photo. "Significantly elevated #EBNA1 IgG levels were detected in serum& CSF of [indivs w/ RR #MultipleSclerosis]... CSF EBNA1 IgG & indices based on specific CSF EBNA1 IgG assoc with CSF albumin or serum EBNA1 IgG assoc w/ total serum IgG" had⬆️sensitivities. https://t.co/fkRO0qiU55 https://t.co/PtHlnwjJKC](https://pbs.twimg.com/media/Gc1RlbRWwAAL08n.jpg)
https://t.co/5HkxGS7BNb
"EBV load and cytotoxic T-cell responses were unaffected."
"Anti-#EBNA1 antibody levels remained below detection limits in B-cell cultures."
"Increased anti-EBNA-1 IgG and reduced 25(OH)D-levels have been observed prior to MS onset."
Exploring the effect of vitamin D3 supplementation on the anti-#EBV antibody response in relapsing-remitting multiple sclerosis #EBNA1 #MECFS #LongCovid
https://t.co/5HkxGS7BNb
Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism #EBV #EBNA1 #MECFS #LongCovid
https://t.co/jkwTZCRKZ2
Epstein–Barr virus is an agent of genomic instability.
Study shows that a protein from #EpsteinBarr virus, #EBNA1, breaks human chromosome 11, producing instability in the genome that might cause a predisposition to #cancer.
https://t.co/R0ep4c4kEk
@Brandon_Beaber 🧐”Effect of high-dose vitamin D 3 supplementation on antibody responses against Epstein-Barr virus in relapsing-remitting multiple sclerosis” #EBNA1 #VitaminD
https://t.co/aamSuxHnly
#Bcells #EBV #CD4 #Tcells #lymphocytes #NK #IFNy #MHC #antigen_presenting_cells #gp42 #MHCII #peptides #neoantigens #autoantigens #autoimmunity #citrullinated #EBNA1 #Th1 #Th2 #mRNA #microRNA #DNA #glycoproteins #gp350 #gp43 #cell_membrane #vesicle
{scavenger hunt / lost & found}

https://t.co/V8swYxwcK3
"Exosomes bind to EBV-latent B lymphocytes or other uninfected B lymphocytes through the interaction of gp350/CD21 and/or g42/MHC-II, releasing their contents into the cellular interior."

New Cell paper - Cell-cycle-dependent #recombinase-like activity of #EBNA1 is required for #replication termination and viral episome maintenance of oncogenic #EpsteinBarrvirus. #EBV Paul Lieberman Lab @TheWistar https://t.co/LC6ElGUYpk
New enzymatic activity of the #EpsteinBarrVirus #EBNA1 protein discovered by @TheWistar lab of Dr. Paul Lieberman is required for replication termination and viral #episome maintenance. Published today in @CellCellPress. https://t.co/TA11th6Wib

#EBV nuclear antigen 1 (#EBNA1) antibody shows #cross-#reactivity with #chloride-#channel #protein #Anoctamin 2 (#ANO2)
- #molecular #mimicry responsible for #pathogenesis of #Multiple #Sclerosis (#MS) ?
#MultipleSclerosis
https://t.co/yQtjUSLurA
https://t.co/zzsUZJ3xbD Featured cover paper @Oncotarget VOL8N5 #virus #EBV #EBNA1 #nasopharyngeal #carcinoma #NPC #survivin #latency
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