Top Tweets for #EMPERORReduced
Available data in #HF suggest:
#ARNI beneficial vs #RASi
- Slower eGFR decline, ⬇ kidney composite
#SGLT2i likely beneficial
- Slower eGFR decline, ⬇ kidney composite in #EMPERORReduced & meta-analysis
#RASi & #SteroidalMRA no benefit
- No change in eGFR slope, ⬆️ kidney AEs
@kamleshkhunti @EASDelearning @JavedButler1 @mmamas1973 @AnastasiaSMihai @hvanspall @AmarPut @AskDrShashank @ACCinTouch @escardio @ABCDiab Comparatively what do we know about ARB/ACEI kidney benefits in HF trials?
SGLT-2 inhibitors in patients with #heartfailure: a comprehensive meta-analysis of 5️⃣ randomised controlled trials
#EMPERORreduced
#EMPERORpreserved
#DAPAHF
#DELIVER
#SOLOISTWHF
#ESCCongress
https://t.co/QUA5NPfuEX

ICFEr en DM2:
Repasando la evidencia y aterrizándola a nuestra práctica clínica diaria
#DAPAHF #EMPERORreduced
@Marisolbravoam2 y José Antonio Parada Barcia

Ketoacidosis and #EmperorReduced & #DapaHf at #ESCardioAsia!
@escardio #cardiotwitter @ESC_Lavinia
Incidence of #Ketoacidosis is not seen in #EmperorReduced and it is only (0.3) in #DapaHF, which only seen in group with #DM but not in nonDM #HF @escardio #ESCardioAsia @APSIC6 @NHMAmd @aayshacader @mirvatalasnag @chinghuisia @keithachanmd @HanCardiomd @J_Hendriks1 @hvanspall

Incidence of #Ketoacidosis is not seen in #EmperorReduced and it is only (0.3) in #DapaHF, which only seen in group with #DM but not in nonDM #HF @escardio #ESCardioAsia @APSIC6 @NHMAmd @aayshacader @mirvatalasnag @chinghuisia @keithachanmd @HanCardiomd @J_Hendriks1 @hvanspall

Empagliflozin in #HFrEF in addition to background therapies & therapeutic combinations in #EMPERORReduced in @TheLancetEndo
#SGLT2i fully additive & complementary to other foundational Rx.
@JavedButler1 @Filippatos @JJheart_doc @lamcardio @FaiezZANNAD
https://t.co/cpMosXlkji
Knowledge transfer can be a slow process. I get a similar email or call at least once a month. And yes, I get on the phone & dutifully send clinical trial summaries to each pharmacy. Every single time. #SGLT2i #HeartFailure #GDMT #DAPAHF #EmperorReduced #EmperorPreserved #Empulse

#EASD2021
#SGLT2i possible mechanism leading to improvements in #HF on
#WorldHeartDay ❤️#WorldHeartDay2021 ❤️
@EASDelearning @EASDnews
#DapaHF
#EmperorReduced

📌Prognostic Importance of NT-proBNP & Effect of #Empagliflozin in the #EMPERORReduced Trial
#CardioEd #CardioTwitter @JACCJournals

Fantastic to have @SantosGallegoMD appraise a substudy of the #EmperorReduced RCT for @AnnalsofIM #ACPJournalClub
The benefit of #empagliflozin is evident across the range of #kidneyfunction in #HFrEF
https://t.co/lfTGX8SFg3
@FaiezZANNAD et al: https://t.co/1XlAi1BnGQ
#SGLT2i

13) Two large RCTs (#DAPAHF #EMPERORReduced) have shown consistent reductions in death & HF events among pts with HFrEF. Robust findings were irrespective of presence or absence of diabetes and background medical Rx. @FaiezZANNAD

4) The answer is choice 4. Three large-scale RCTs (#DAPAHF, #EMPERORReduced, #DAPACKD) have evaluated patients without T2D including prediabetes, however all required pts to have established #HF or #CKD.
In case you missed it: hear a 5-min podcast summary of the latest secondary analysis of #EMPERORreduced by @JavedButler1 et al.
🎙️Listen & subscribe: https://t.co/96MeaXU9Wk
#Empagliflozin improved CV outcomes in HFrEF regardless of baseline health status @ESC_Journals

Are #SGLT2i Simply "Smart Diuretics"?
Amounting evidence, including from #EMPERORReduced in this issue of @JACCJournals, argues against diuresis as a dominant mechanism of benefit.
Packer et al.: https://t.co/1XKHXAjdWh
Editorial with @MkosiborodMD:
https://t.co/dSO2wZyAB7

📌Interplay of MRAs & #Empagliflozin in #HeartFailure: #EmperorReduced
🔸MRAs didn't influence the effect of empagliflozin to ↘️ adverse heart failure & renal outcomes
🔸Less discontinuation of MRAs in the Empa Group
@JACCJournals

Hopefully, @JJheart_doc ‘s ears were burning today as we discussed the Expert Decision Pathway for #HFrEF in context of our #IMEDJC on #EMPERORReduced @NorthShoreWeb
Dr Chris did an excellent job in study analysis & in the context of both your work & @gcfmd ‘s work!

⚠️ Influence of neprilysin inhibition on the efficacy & safety of #empagliflozin #EmperorReduced
🔹Benefits of #Empa are NOT ↘️ in 👥 who are receiving #SacubitrilValsartan ‼️
#HeartFailure #CardioEd #CardioTwitter

Heart failure + Empagliflozin + Coffee 💜😉 #EMPERORReduced
Honoured to discuss #HealthStatus outcomes of #EMPERORREDUCED w/ @JavedButler1 after his LBS session at #AHA20! From #KCCQ to clinically/minimally important differences to multiplicity & how to get the #HFrEF cocktail right, we covered a lot! #SGLT2is
https://t.co/x8gLltLnPo

How can you measure health status of patients in clinical trials?
https://t.co/NrofKvP4YL
Don’t miss this interesting #AHA20 discussion as host, @hvanspall meets with Dr Javed Butler to discuss a pre-specified analysis from the EMPORER-Reduced study
#CardioTwtiter #MedTwitter
Such a pleasure to have Dr. Milton Packer attend Journal Club on the #EMPERORReduced trial. Thanks for the great discussion, and thanks to our stellar fellow @NHoeting for presenting! 👏

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