Top Tweets for #EXACTtrial
π§΅ Oxygen post cardiac arrest is controversial. These patients often remain on supported ventilation, with an FiO2 of 1.0, during their transport to the hospital to prevent hypoxia and secondary brain injury.
#EXACTTrial #FOAMed #ICU #OslerALS #medtwitter #FOAMcc #FOAMresus
So many trials on this topic... going to need to wrap my brain around #BOXTrial, #PILOTtrial, the new #EXACTtrial... and #MegaRox enrolling...
thoughts from y'all?
Pilot: https://t.co/TXInOtlP9v
Box: https://t.co/NFqycxtxs9
Exact: https://t.co/ogS3Em7tfr
look at this!
in 5 out of 6 large existing #RCTs on O2 #oxygen survival is slightly in favor of higher oxygenation groups, including the #PILOTtrial just published on the @NEJM https://t.co/aDyRaeJ5Bs
There is still equipoise to complete ongoing trials like @MegaROXtrial

A hypoxic episode prior to ICU was observed in 31% in the intervention group vs 16% in the control (p<0.001)
Although the RCT was early terminated due to COVID, findings donβt support a SpO2 target of 90-94% in the pre-h setting after ROSC
#ResusTwitter #FOAMcc #EXACTtrial
#EXACTtrial just presented at #LIVES2022
π Paramedics randomised OHCAs to a target SpO2 of 90-94% or 98β100% after ROSC during pre-hospital and ED care
β‘οΈ Survival 38% with SpO2 90-94% vs 48% with SpO2 98%-100% (p=0.05)
π https://t.co/NeQu0PtKP1
#ResusTwitter #FOAMcc π§΅π

#EXACTtrial just presented at #LIVES2022
π Paramedics randomised OHCAs to a target SpO2 of 90-94% or 98β100% after ROSC during pre-hospital and ED care
β‘οΈ Survival 38% with SpO2 90-94% vs 48% with SpO2 98%-100% (p=0.05)
π https://t.co/NeQu0PtKP1
#ResusTwitter #FOAMcc π§΅π

Our clinical research team is studying an investigational one-time administration of gene therapy for treatment of refractory angina.
Read more about this study: https://t.co/KFTqrqE2Yh
#THI #THICCR #ExactTrial

THI's Center for Clinical Research is conducting a clinical trial that will evaluate the safety of a gene therapy treatment in patients with Refractory Angina secondary to Coronary Artery Disease.
Learn more about the study: https://t.co/KFTqrqE2Yh
#THI #THICCR #ExactTrial

Great work from our T&O Trainee Principal Investigator of the year @doctorthomaschr πππ» @nhsuhcw @joshivam @corintechnology @UHCW_RandD #EXACTtrial
Prof Jerry Nolan discussing the overuse of oxygen in STEMI and itβs potential deleterious effects. What is the impact of high flow oxygen in #OHCA? #EMS2018 #stemi #oxygen #copenhagen #exacttrial

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