Top Tweets for #GOLGI
Two Golgi markers. One MINFLUX acquisition. The new abberior DNA-PAINT FLASH 2color kit resolves Giantin and GM130 simultaneously in 3D. Vero cells · MINFLUX · 3D
#MINFLUX #DNAPAINT #Golgi #FLASHPAINT
Mostra "Più vasto del cielo. Camillo #Golgi, l'uomo che vide la meraviglia del cervello"!
🎟️dal 10/10/26 al 31/01/27: apertura mostra
🚶♀️dom 11/10: mostra visitabile (10.00-18.00),visite guidate a 5€ (11.00 e 15.30). Speciale: divertiti con l'Escape Room al Museo Golgi (16.00)!
Pengwei Zhao, Mengyuan Zhang, Rongbin Ding et al. @ZJU_China develop constitutive and inducible #Golgi reporter mice that enable in vivo visualization of Golgi architecture and Golgiphagy at single-cell resolution. https://t.co/N2OSL3C0Lr
#Technology #Organelles
Alu-mediated SPAST deletion disrupts SLC30A6 expression and ZnT6-dependent #Golgi zinc transport, linking zinc dyshomeostasis and Golgi fragmentation to protein aggregation and a targetable vulnerability in #Neurodegeneration. @UST_Korea
#STTT #OpenAccess: https://t.co/0FXcMUStsS
Ryan C. Vignogna and Christopher Fromme identify GAP activity in several DENN domain proteins, revealing unexpected functional diversity within this protein family. https://t.co/mNaQ05av4z
#GolgiTime #GTPases #Migration #Biochemistry #StructuralBiology #Golgi
Spotlight: Bhaskar Naidu et al (https://t.co/Au2ipuOMUj) show that the #Golgi responds to the mechanical force of cell spreading by increasing its secretory output, sustaining spreading thru a self-reinforcing feedback loop. Hausser discusses the study: https://t.co/LC7qZ4iXiy
Excited to share our paper, now out in @JCellBiol!🎉
Co-led with George Galea at @embl , we uncover a new layer of spatiotemporal regulation of the #DNADamageResponse between the Golgi and the #Nucleus, revealing an active role of the #Golgi in #DNArepair.
https://t.co/asgxfU0y54
Bhaskar Naidu, Vera Lillo, Manneville, Miserey, Campelo et al. show that extracellular mechanical forces reciprocally regulate #Golgi function. The study reveals a feedback pathway by which Golgi export supports cell spreading and mechanoadaptation. https://t.co/u4ZLhd5TTu
Here you can see a crystal structure of PITP protein covalently bound to microcolin H (PDB code: 9TA5)
Rendering by Francisco J. Enguita (@fenguita) made with #ProteinImager
#SciArt #molecularart #membrane #pitp #microcolin #secondary #metabolism #xray #golgi #calcium
Yang et al. show that the secretory pathway kinase Fam20C is retained in the #Golgi via Fam20A-mediated membrane anchoring. Mislocalizing Fam20C alters #secretome phosphorylation, leading to reduced milk quality and subsequent growth retardation in pups. https://t.co/3gvfYk9jUk
Que sí, que sí...que hoy es San Fermín, pero también el cumpleaños de Camillo Golgi, que nació #taldíacomohoy de 1843.
Padre de la "reacción negra" que utilizó #Cajal, compartieron el @NobelPrize en 1906.
#ramónycajal #ramonycajal #golgi
The AXL-Golgi story...
has two parts, both of which are now published.
1) AXL receptor tyrosine kinase regulates Golgi organization and function via an adhesion-Arf1 signaling axis in breast and lung cancer cell lines
https://t.co/EN0RNV1BJY @BiologyOpen
2) Differential AXL expression and Arf1 regulation control stiffness-dependent Golgi organization in breast cancer cells
https://t.co/DrlvS4293x @J_Cell_Sci
Together, they make for a comprehensive story identifying the role of AXL in controlling Golgi organization and its regulation by mechanosensory cues (matrix stiffness).
Work started as a simple screen by Prachi to pick AXL as a gene of interest, taken forward by @ArnavSaha19 and @Tush96rkhane. Supported ably by many others. It's also nice to be able to use data from Vibhas's @SVibha1 studies in this paper, as she identified the adhesion-Golgi connection many years ago.
Congratulations to all involved in this study, which was challenging and exciting in equal measure.
@emboreports @JNuchel Here, we identify #GRASP55—a protein previously described to be involved in #Golgi morphology and in unconventional protein secretion (aka #UPS; see also PMID 34245671)—as a gatekeeper of lysosomal enzyme sorting at the Golgi.
Stalder, Pereira, Gershlick et al. @Cambridge_Uni uncover new regulators of #Golgi-to-plasma membrane transport, showing that a PTPN23-dependent #ESCRT pathway is essential for secretion of membrane & soluble cargoes, including hormones & antibodies. https://t.co/NtMgBujKHf
Hoy se cumple el #centenario de la muerte, en Pavía, de Camillo #Golgi, padre de la reacción negra y que compartió el @NobelPrize con #Cajal.
"[...] creador del método con el cual di yo cima a mis descubrimientos más resonantes"
Más info:
https://t.co/VwnGOgHBzi
![ryc_ayerbe's tweet photo. Hoy se cumple el #centenario de la muerte, en Pavía, de Camillo #Golgi, padre de la reacción negra y que compartió el @NobelPrize con #Cajal.
"[...] creador del método con el cual di yo cima a mis descubrimientos más resonantes"
Más info:
https://t.co/VwnGOgHBzi https://t.co/NJcvxUYTm0](https://pbs.twimg.com/media/G_IWkRkWoAAfVay.jpg)
Kim, Parolek, and Burd @YaleCellBio show that depletion of #cholesterol increases #sphingomyelin synthesis as a result of increased coatomer II–mediated endoplasmic reticulum-to-#Golgi #trafficking of #ceramide, the precursor to sphingomyelin. https://t.co/FgqgGIHuvo
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