#GlycanGate - Twitter Hashtag

almost 5 years ago

Very cool that this @Vir_Biotech monoclonal antibody works against #Omicron & binds an epitope containing the N343 glycan we showed plays an important functional role as a #GlycanGate for RBD opening @McLellan_Lab @ltchong @Terrasztain @fiona_chembot @LCasalino88

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Terra Sztain, PhD @Terrasztain

about 5 years ago

#GlycanGate

Rommie Amaro @RommieAmaro

about 5 years ago

#compchem #glycotime strikes again... Now showing how the N343 glycan gates the opening of the #SARSCoV2 spike! https://t.co/1bAyykvVD4 Feat all-star 🤓team @Terrasztain @McLellan_Lab @ltchong @LCasalino88 @fiona_chembot @JoryGoldsmith @joachimfrank @McCool_Seamus & co A 🧵

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Terra Sztain, PhD @Terrasztain

over 5 years ago

Pandemic painting #SciArt #SARSCoV2 #GlycanGate

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Terra Sztain, PhD @Terrasztain

over 5 years ago

Here's a close up of the N343 #GlycanGate Thanks @LCasalino88 for the beautiful VMD movies!

Rommie Amaro @RommieAmaro

over 5 years ago

Analysis of these pathways & experiments reveal R408, D405, D427 participate in the RBD opening mechanism & the N343 glycan acts as a “gate” – initially blocking but then pushing up the RBD by intercalating between residues F490, Y489, F456, and R457 of the ACE2 binding motif

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Rommie Amaro @RommieAmaro

over 5 years ago

🚨 In a new @biorxivpreprint with @McLellan_Lab @ltchong @Terrasztain @LCasalino88 @fiona_chembot @JoryGoldsmith, we show how a glycan gate (at position N343) controls the opening of the #SARSCoV2 spike protein #GlycanGate #glycotime https://t.co/KPhj2vFgg6 🧵:

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