Top Tweets for #H2Blockers
Avoid PPI in SLE patients because of Risk of #SubcutaneousLupusErethymatosis
And #Osteoporosis instead use #H2Blockers
For rapid resolution of lupus rash use #Anifrolumab but donβt forget to vaccinate your patient for #Zoster and #Covid19
#ACR24
1. π #PPIs or π #H2Blockers: Which one impacts the gut microbiome more? π€ New RCT in @Gut_BMJ compares their effects on gut bugs & oral-to-gut transmission. #GITwitter #microbiome
2.π¬ 49 healthy volunteers π§βπ€βπ§ were randomized to receive either a PPI or an H2RA daily for a week. Saliva π§ and stool π© samples were analyzed before & after.
3. The results are in! π PPIs caused greater gut microbiome disruption π₯ than H2RAs, with a greater increase in oral bacteria migrating to the gut π¦ β‘οΈ
4. π² #PPI use even led to the transmission of Fusobacterium nucleatum to the gut in some participants! This bacterium is linked to #colorectalcancer
5. Important to note: H2RA use did not lead to significant changes in the oral microbiome. π€ Suggests the gut microbiome shifts are likely due to PPI mechanisms.
6. This RCT provides more evidence that long-term #PPI use could have unintended consequences for the gut microbiome. π€ Time to consider #H2Blockers as an alternative option?
Allergic people in the USA: anyone able to get hold of #nizatidine?I understand thereβs a supply squeeze. Canβt tolerate famotidine. Any thoughts on alternatives, please? Iβm on ketotifen, so not sure if #Cromolyn is possible? TY π #H2Blockers #MCAS #LongCovid
Proton-pump inhibitor vs. H2-receptor blocker use and overall risk of #CKD progression. #PPI #H2blockers #openaccess @BioMedCentral
https://t.co/iIMfSLnyQg
Good editorial by @CMichaelWhite2 & @AVHernandezDiaz @UConnPharmacy
#Ranitidine & Risk of N-Nitrosodimethylamine (#NDMA) Formation https://t.co/hq460q8ykk
Addressing these 2π just out @JAMA_current
>> https://t.co/6S5rDLrl3T
>> https://t.co/ffkPgzS4Ux
#H2blockers #heartburn
#Infant #AcidSuppression use is associated with the development of #EosinophilicEsophagitis https://t.co/uk0Zyoyxrq #PedsGITwitter #EoE #ProtonPumpInhibitors #PPI #H2Blockers #GERD
ICYMI: @doctorira spoke with @bswhealth Co-directors of Center for Esophageal Diseases, Dr. Rhonda Souza & Dr. Stuart Spechler about #GERD, #H2Blockers for #COVID research + more. Replay 8-8:30pmET / 5-5:30pm Pacific @SIRIUSXM
@DrCeSarcoma @CCR_AACR Absolutely! I have to thank our #clinicalpharmacists everyday in clinic for counter checking #concomittant meds that the patients are taking and for reinforcing the need to #stop #PPIs and to have significant time intervals between #H2blockers and #pazopanib
@lee_jasonk @CBCNews It would also be helpful to educate the public on #mythsvsfacts on the use of therapies such as #steroids and #H2Blockers in #anaphylaxis
Acid reflux drug (PPI) linked to more than doubled risk of stomach cancer β study in Gut . Alternatives? #H2blockers ?Demand for #Antireflux surgery might rocket @obsmuk #obsmuk https://t.co/smfjVIfWtI
Still brilliant story from a modest son of #Fife who got a #Noble prize for work on #betablockers & #H2blockers #CardioEd @radcliffeCARDIO https://t.co/D9YpsaLnYR
The accidental discovery of beta-blockers https://t.co/i6K8p03TqX (@webofstories).
@rcpsglasgow Honorary Fellow, James black born #OTD 1924
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