Top Tweets for #HTAN2018
Snyder: Combining single cell RNA-Seq and ATAC-Seq allow linking promoters with accessibility elements - assign regulatory elements with genes with high confidence #HTAN2018
@theNCI Together with @Danapeer1 and colleagues @mskcc we will build atlases of pancreatic and lung cancer metastasis, the top 2 causes of cancer death in the US by 2020. @PanCAN @lustgartenfdn @LungAssociation @TheALCF @letswinpc #HTAN2018
Orit Rozenblatt-Rosen recommends using https://t.co/pi3xR3HCpS to share SOPs. There is even an HTAPP specific site there. #HTAN2018
Happy to see that #PancreaticCancer is a part of @theNCI #HTAN2018 thanks to @ciacobu & Dana Pe’er @sloan_kettering
#PancreaticCancerAwarenessMonth
Dana Pe'er and Christine Iacobuzio-Donahue are up next to discuss their project investigating the transition to metastasis using warm autopsies for lung and pancreatic cancer #HTAN2018
Every metastasis (from the warm autopsies) is cut into 1cm slices. Each slice is cut into 1x1cm cubes. Then each 1cm^3 cubes is cut in half and saved as blocks. They now have 11K samples banked. Every block gets a diagnosis #HTAN2018
Iacobuzio-Donahue: Cell lineage (type) plasticity is a common feature of carcinomas, which probably facilitates drug resistance #HTAN2018
Dana Pe'er and Christine Iacobuzio-Donahue are up next to discuss their project investigating the transition to metastasis using warm autopsies for lung and pancreatic cancer #HTAN2018
Aviv Regev asks the interesting question: what are the molecular determinants of morphological features that pathologists recognize in cancers? #HTAN2018
Excited to be part of the Human Tumor Atlas Network kick-off meeting. Follow #HTAN2018 and @NCIHTAN for more information.
single cell THS-Seq developed by K. Zhang (Sos et al. @GenomeBiology 2016), shows open chromatin regions better than ATAC-Seq #HTAN2018
You can read more about the National Cancer Institute's human tumor atlas network (@NCIHTAN) at https://t.co/vqsCgF9THL #HTAN2018
Excited to be at the kick off meeting for the Human Tumor Atlas Network at the NCI! Changing our understanding of precancers!
#HTAN2018
.@NCIHTAN is holding its kickoff meeting to develop tumor atlases for both pre-cancers and cancers. This is the next generation of the TCGA (genome atlases) and should provide the community with a ton of multi-modal data to help understand progression #HTAN2018
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