#IntrinsicallyDisorderedProtein - Twitter Hashtag

3 months ago

👏Newly Published Paper👏 “A New Anatomy of Autophagic Clearance: On the Roles of Intrinsic Disorder in the Membrane-Less on Membrane-Encapsulated Mechanism” by Vladimir N. Uversky from @USouthFlorida, et al. ▶️https://t.co/arm7SKFlSF #Autophagy #IntrinsicallyDisorderedProtein

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Daniel Shapiro @theDanShapPhase

over 1 year ago

We fused the human Pumilio2 RNA-binding protein to an elastin-like polypeptide, a synthetic #intrinsicallydisorderedprotein (read: protein noodle), and used this fusion to sequester mRNA tagged with a Pum recognition sequence (PRS) into a biomolecular condensate (2/🧵)

theDanShapPhase's tweet photo. We fused the human Pumilio2 RNA-binding protein to an elastin-like polypeptide, a synthetic #intrinsicallydisorderedprotein (read: protein noodle), and used this fusion to sequester mRNA tagged with a Pum recognition sequence (PRS) into a biomolecular condensate (2/🧵) https://t.co/7sECfqtCUH

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CPD Weill Cornell Medicine-Qatar

@cpd_wcmq

over 3 years ago

Welcome to today’s discussion on “Intrinsically Disordered Proteins in Human Diseases” in the “Protein Misfolding Diseases and Neurodegeneration: From Experimental Approach to Clinical Therapy” series, led by Dr Vladimir Uversky from @USFHealthMed #IntrinsicallyDisorderedProtein

cpd_wcmq's tweet photo. Welcome to today’s discussion on “Intrinsically Disordered Proteins in Human Diseases” in the “Protein Misfolding Diseases and Neurodegeneration: From Experimental Approach to Clinical Therapy” series, led by Dr Vladimir Uversky from @USFHealthMed #IntrinsicallyDisorderedProtein https://t.co/9DUl12j7c7

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Instituto de Química Física Blas Cabrera @iqf_csic

over 4 years ago

#IQFRPaper Global Structure of the Intrinsically Disordered Protein Tau Emerges from Its Local Structure Collaboration with @UZH_Chemistry @UZHPhysics @DZNE_en @MPIbp @goetheuni @uni_mainz @univienna #tau #intrinsicallydisorderedprotein #tauopathy 🔗https://t.co/DrMxCg770v

iqf_csic's tweet photo. #IQFRPaper Global Structure of the Intrinsically Disordered Protein Tau Emerges from Its Local Structure

Collaboration with @UZH_Chemistry @UZHPhysics @DZNE_en @MPIbp @goetheuni @uni_mainz @univienna

#tau #intrinsicallydisorderedprotein #tauopathy

🔗https://t.co/DrMxCg770v https://t.co/ejaqR3wODu

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Journal of Biological Chemistry @jbiolchem

over 5 years ago

Kamps et al. show that the intrinsically disordered N1 domain is necessary and sufficient for liquid–liquid phase separation of PrP. – #Neurodegeneration #Prions #aggregation #IntrinsicallyDisorderedProtein https://t.co/LwykP7XIog @ruhrunibochum

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Amberley Stephens @AmbsS140

over 5 years ago

This paper was fascinating to work on. For #IntrinsicallyDisorderedProtein the role of the solvent is VERY important and often overlooked. Can the presence of different ions and water mobility in cells influence disease outcome? #parkinsons #neuroscience

Molecular Neuroscience Group @mng_ceb

over 5 years ago

Our first 2021 #preprint 'The mobility of water influences protein misfolding' We show ions influence water motions which are inextricably linked to protein dynamics and therefore misfolding propensity. A thread below of the work led by @AmbsS140 https://t.co/0gFUt8ucwf