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Iwase Laboratory @Iwase_Lab
We IDed 4 NDDs with ectopic germline expression in the brain #ICF1 #Kleefstra #MDS #MRXSCJ. Mutations in genes #DNMT3B #G9A #GLP #MECP2 #KDM5C may lead to germline gene derepression & a severe identity crisis of brain cells, interfering with normal development.
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