Top Tweets for #Maintenancetherapy
4/4 The approval adds a HER2-selective TKI to dual-antibody maintenance after induction. The open question is how this strategy will sit alongside other 1L HER2+ approaches as OS data mature.
#HER2 #Tucatinib #TKI #Seagen #MaintenanceTherapy
SCCA2 reflects patient‑reported burden in mild atopic dermatitis
Why it matters:
In mild #AD, #ClinicalScores often miss how children actually feel. #Biomarkers that capture patient‑experienced #symptoms can improve monitoring during #MaintenanceTherapy.
What the study found:
• In 69 children with mild AD, POEM scores varied widely despite uniformly mild EASI.
• SCCA2 correlated with POEM at baseline - TARC did not.
• The SCCA2–POEM link was strongest at Day 3, weakening by Day 7, showing short‑term sensitivity to symptom changes.
Takeaway:
#SCCA2 may help identify early increases in symptom burden in children with #mildAD under maintenance treatment.
Learn more here 🔗 https://t.co/cqZn6dVvcm
#AtopicDermatitis #Eczema #PediatricAllergy #PAI_Journal #patientreportedburden #POEM #EASI #originalarticle
⏳ 6/9 Maintenance Therapy: RTX is superior to AZA in preventing relapses, but relapses occur after stopping RTX. Optimal duration of RTX is still unclear. #MaintenanceTherapy #Rituximab
Discussing crucial aspects of #1st-line treatment of #advancedpancreaticcancer including #treatmentchoicecriteria, #Maintenancetherapy, #toxicityprofile of different regimens available.
#PDAC #pancreaticcancer
@VuMedi
https://t.co/4DT2qPBRQ6
ViiV Healthcare shares data for two-drug regimen for HIV-1 maintenance therapy https://t.co/1cIgYIhmBK #GSK #HIV #maintenancetherapy
MRD status is one of the most powerful prognostic factors in #MultipleMyeloma and monitoring MRD status may help to guide treatment management. In this video, Dr Bruno Paiva discusses the prognostic value of MRD dynamics during #MaintenanceTherapy.
https://t.co/Sdjial9gn4
🆕 in @BloodJournal: Children with #ALL who live in extreme poverty & undergo #maintenancetherapy face an almost 2x greater risk of relapse when compared to their counterparts of higher socioeconomic status. Read more now: https://t.co/8AZGrG6mQO
A Celebratory San Pellegrino tonight !bone #marrowaspiration ✅ #interthecalMtx ✅ an MRI & heart scan to go , in twenty days my #mrd assessment & #maintenanceTherapy can start . Its back to work normal life & freedom! #mycancerjourneyilias #fuckcancer
Using 1 gram #Rituximab as #MaintenanceTherapy for inflammatory neurologic conditions such as #NeuromyelitisOpticaSpectrumDisorder (#NMOSD) and #MultipleSclerosis (#MS) appears to be effective maintenance therapy. Study in @SclerosisAnd.
Read more here: https://t.co/AT1HFrxjqy
#Immunoadsorption may be a promising #MaintenanceTherapy in #NeuromyelitisOpticaSpectrumDisorder (#NMOSD). Study in @TANeurolDisord
Read more: https://t.co/Dj7UgOg9Vr
#DevicsDisease #AutoimmuneDisease #NeuromyelitisOptica #Ophthalmology #Neurology #NeuroTwitter
Happy to present our accepted poster: Impact of Coronavirus (COVID-19) pandemic on maintenance therapy for FL and MCL. Thanks to all my colleagues who participated in this study #ASH22 #COVID #Maintenancetherapy #FL #MCL
#chemo7 48h #docorubucin #vincristine #dexamethasone continue part of this #hypercvad regimen. Question is whether to do a #stemcell transplant OR #maintenancetherapy ANY ADVICE APPRECIATED #stayhard #myCancerjouneyilias #stemcelltransplant #livethePresent
One of the reasons to reconsider giving same duration of #maintenancetherapy all subtypes of #ChildhoodALL.
EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy https://t.co/arHgxm1Bik
29c) @cochranecollab #metaanalysis (safety comparison)
#PARPi vs placebo
📍RR 2.62; 95% CI 1.85–3.72 (low‐certainty evidence)
👉PARPi #MaintenanceTherapy may result in ⬆️incidence of any severe AE (51% vs 19%)
29a) 👀Check out this @cochranecollab #metaanalysis on the use of #PARPi as #MaintenanceTherapy in recurrent #OvarianCancer (N=1677)
🔗🔓https://t.co/xegR78GaKk
PARPi vs placebo
📍PFS: HR 0.34; 95% CI 0.28–0.42 (high‐certainty evidence)
👉No evidence of PD at 12 mos = 37% vs 5.5%
28g) #ARIEL3 important points
👉#Rucaparib #MaintenanceTherapy in recurrent #OvarianCancer led to ⬆️PFS & delayed the need for subsequent Tx regardless of HRD status & other clinical prognostic factors
👉Tolerable safety profile w/ ⬇️incidence of Tx discontinuation due to AEs
28h) #NOVA important points
👉⬆️PFS w/ #niraparib (NIR) #MaintenanceTherapy beyond 1st progression
👉No OS difference (however, not powered for OS; confounded by ⬆️crossover & missing data)
👉Safe long-term use of NIR, w/ ⬇️hematologic AEs after 1 yr of Tx
25) Several RCTs have shown a significant ⬆️PFS w/ the use of #PARPi as #MaintenanceTherapy for patients w/ platinum-sensitive recurrent #OvarianCancer (regardless of #BRCA mutation status):
👉#Study19
👉#SOLO2
👉#NOVA
👉#ARIEL3
See 🔓https://t.co/cSrScHkNXY
24) If in CR/PR after platinum-based recurrence Tx, @NCCN recommends #MaintenanceTherapy w/ #PARPi in patients w/ platinum-sensitive #OvarianCancer who have:
👉Completed ≥2 lines of platinum-based Tx
👉➕#BRCA mutation
👉No prior progression on a PARPi
https://t.co/dZLwboVjK4
23) 👀BONUS: Look at this simplified algorithm summarizing the frontline #MaintenanceTherapy options for advanced stage, high-grade #OvarianCancer following response to 1L platinum-based chemo
🔗🔓https://t.co/OohWg2MTKJ
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