Top Tweets for #MasterDAPT
Register to our interactive sessions led by global experts discussing new antithrombotic recommendations on #HBR patients. Explore complex #PCI strategies, DES selection, and insights from MASTER DAPT.
🌐 https://t.co/58WaV3OukC
#MASTERDAPT #cardiotwitter
Great secondary analysis set on #MasterDAPT ! Thanks for sharing @mirvatalasnag @vlgmrc
@JAMACardio #cardioTwitter #HBR #women
Abbreviated or Standard DAPT by Sex in Patients at HBR
A Prespecified Secondary Analysis of #MASTERDAPT
Our work published @JAMACardio
🔗 https://t.co/ZdaVZZg8Ie
@antoniolandii @vlgmrc @alaide_chief @DrLucaTesta et al
📮Ischemic & bleeding risks were comparable
📮There was no significant interaction for net adverse & bleeding events
📮Significant heterogeneity observed for MACCE with a benefit of abbreviated treatment in women but NOT in men

Abbreviated or Standard DAPT by Sex in Patients at HBR
A Prespecified Secondary Analysis of #MASTERDAPT
Our work published @JAMACardio
🔗 https://t.co/ZdaVZZg8Ie
@antoniolandii @vlgmrc @alaide_chief @DrLucaTesta et al
📮Ischemic & bleeding risks were comparable
📮There was no significant interaction for net adverse & bleeding events
📮Significant heterogeneity observed for MACCE with a benefit of abbreviated treatment in women but NOT in men

@djc795 @Hragy @SACIS_KSA @escardio @PCRonline @TCTMD We’ve now enrolled in several international studies the latest was #MASTERDAPT & CROs usually ensure everything is up to par: conduct routine site visits, review the data w stringent follow up w queries that need answering within a time frame & reporting of events to IRBs
Prof Mamas giving talk on clinical implication and prognostic value of identification of HBR patients. #MASTERDAPT @mmamas1973 #CardioTwitter @purviparwani @mirvatalasnag

One-month dual antiplatelet therapy vs ≥3 months dual antiplatelet therapy in #HighBleedingRisk patients did not differ in ischemic risk but lowered bleeding risk: https://t.co/EK29mgpa6M
#JACC #MasterDAPT #cvMI #cvACS #CardioTwitter @FelixMahfoud @GoranEBC @vlgmrc

A 1-month #DAPT in #HBR pts presenting with #MI results in ↔️ NACE & ↔️ MACCE rates but ⬇️ #bleeding compared to nonabbreviated DAPT https://t.co/CqYFtiHxsi #Cardiotwitter #MedEd @vlgmrc @mmamas1973 @mirvatalasnag @DFCapodanno @Drroxmehran @HeartOTXHeartMD @CMichaelGibson

#MASTERDAPT provides insights👇on the management of #HBR pts treated with #complex #PCI; #DAPT discont. at 1 month ↔️NACE&↔️MACCE & ⬇️🩸vs standard DAPT, regardless of PCI or patient complexity👉https://t.co/OhrLqYX2oo #CHIP #bleeding @mirvatalasnag @mmamas1973 @vlgmrc

@sbrugaletta @PCRonline @TCTMD @mmamas1973 @alaide_chief @HolgerNef @thiele_holger @DFCapodanno @djc795 @GreggWStone @secardiologia @EAPCIPresident @Ortega_Paz @nickaram #MASTERDAPT 15
It‘s a wake up call..once a patient is assigned to one strategy, it’s difficult to change & abbreviate DAPT
Also our patients are committed to DAPT (I think we do too much education re ST & unnecessary discontinuation for dental work etc that it becomes engrained)
#ISCHEMIA-CKD EXTEND : Revascularization ⛔️ benefit vs. Conserv Str in Stable CAD w/Advanced CKD at 5 Yrs
#MASTERDAPT : Short DAPT ⏬ Bleeding , ⛔️ isch penalty vs. Std DAPT at 15 Mnths
#ESCCongress wrap-up by my friend @KardiologieHH 👇
#ACCFIT #ACCIC #SCAIWIN #ACCEarlyCareer
Follow this #CardioTwitter #Thread
to get an overview of ALL
🚨#ESCcongress #HotLineSessions🚨
Including:
➡️14 #OnePager #CongressCards
➡️Links to on-demand stream
➡️Jorunal weblinks
➡️Hashtag of the author/presenter
PART 1 ⬇️

8.2/ #15-month results of the #MASTERDAPT trial
📕🔗: NOT YET PUBLISHED
On-demand ESC 📺: https://t.co/W0GB1JEgvn
By: @vlgmrc
#ESCcongress
#MASTERDAPT Trial🔥
‼️ DAPT Duration post-PCI (1 vs 6 months) ‼️
✅1 month DAPT non-inferior to 6 months
✅No difference in composite (☠️, stroke, MI, or 🩸)
✅Higher⬆️major bleed in 6 month DAPT (9.4% vs 6.5%)
#ESCCongress #esc2022 #ESC22 #MedTwitter #CardioTwitter #ESC

#ESCCongress
#MASTERDAPT 15 mo results
📩 APT influenced by prior
allocation to abbreviated or standard >carry-over reflex
against evidence & guidelines
📩Standard gp continued DAPT after 12mo w/o ischemic events
📩APT intensity influenced by perceived ischemic risk not 🩸 risk

Final 15 month results of MASTER DAPT on their way today at ESC…ready for additional information on how well or bad 1 month DAPT looks like in HBR patients at long-term? @masterdapt @mirvatalasnag @mmamas1973
@vlgmrc @CERC_CRO @mc_morice #MASTERDAPT 15 month data are out and showed consistency with12 month data showing no increase in NACE and MACE but reduction in bleeding with 1 month DAPT in HBR patients @escardio

#MASTERDAPT #abbreviated #DAPT High 🩸risk pts #HBR 15mo F-up @vlgmrc @mmamas1973 @DFCapodanno @Drroxmehran @DavidLBrownMD @HeartOTXHeartMD @CaoDavide @MattiaGalli10 @FeliceGragnano
#HOTLINE #MASTERDAPT
15 month results at #ESCCongress
👉🏽DAPT w/ PCI: abbreviated 🆚 standard
👉🏽APT: ⬆️ prolonged over time (incl in OAC)- less likely to d/c despite guidelines in standard group
👉🏽⬆️🩸 in standard
👉🏽NACE &MACCE similar at 15 m

#MASTERDAPT #ESCCongress
Conclusion:
👉🏽APT influenced by prior allocation standard 🆚 abbreviated tx
👉🏽majority in standard group continued DAPT beyond 12 m
🫀 Important that duration of #DAPT defined upfront to avoid carry over and ⬆️ risk 🩸 bleed
@Steph_Achenbach

#HOTLINE #MASTERDAPT
15 month results at #ESCCongress
👉🏽DAPT w/ PCI: abbreviated 🆚 standard
👉🏽APT: ⬆️ prolonged over time (incl in OAC)- less likely to d/c despite guidelines in standard group
👉🏽⬆️🩸 in standard
👉🏽NACE &MACCE similar at 15 m

@CERC_CRO Yes we are ready for this additional info and excited @DragicaPaunovi2 @mc_morice @AsPlume95 #MASTERDAPT
Final 15 month results of MASTER DAPT on their way today at ESC…ready for additional information on how well or bad 1 month DAPT looks like in HBR patients at long-term? @masterdapt @mirvatalasnag @mmamas1973

Final 15 month results of MASTER DAPT on their way today at ESC…ready for additional information on how well or bad 1 month DAPT looks like in HBR patients at long-term? @masterdapt @mirvatalasnag @mmamas1973
Duration of #antiplatelet therapy after complex #PCI in patients at high #bleeding risk: a #MASTERDAPT trial sub-analysis https://t.co/yYmpbciNBF @vlgmrc @DFCapodanno @Drroxmehran @CMichaelGibson @DLBHATTMD @HeartBobH @DrSethdb @ajaysmd @DrSheilaSahni @DocSavageTJU

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