Top Tweets for #MegabaseSpark
We are excited to share another #MegabaseSpark submission, titled 'Bio-Based Petrochemicals' from @sean_wirt: "We plan to survey enzymes for activity on non-native substrates, enabling the construction of novel metabolic pathways for bio-based commodity chemicals traditionally derived from petroleum. This research supports the transition to a robust bioeconomy." Like and repost if you think this idea is interesting! #SynBio #SyntheticBiology #DNA
We are excited to share another #MegabaseSpark submission, from @ChrisBatianis: "We wire cell growth to enzyme function: if the enzyme fires, the cell thrives. Thousands of variants turn growth into activity data that train LLM models to design better proteins. Synthesised AI-guided hits push sustainable manufacturing forward." Like and repost if you think this idea is interesting! #SynBio #SyntheticBiology #DNA
We are excited to share another #MegabaseSpark submission, from @AmodRBhat: "Tick-borne flaviviruses are stealthy, neglected threats endemic to me but ignored globally. Tired of watching research stall behind biosafety barriers, I intend to engineer "MiniFlaviReps" that are replication competent VLPs but don't require hazmat suits to conduct research.😁" Like and repost if you think this idea is interesting! #SynBio #SyntheticBiology #DNA
With the deadline approaching, we are excited to share another #MegabaseSpark submission, from @HansGerstmans: "Synthetic refactoring and optimization of a biosynthetic gene cluster encoding a potent anti-breast cancer natural product, to improve potency and production in a breast microbiome-resident bacterium."
Like and repost if you like this idea! #SynBio #SyntheticBiology #DNA @KU_Leuven @VIB_microbes
We welcome the first ever #MegabaseSpark submission, from @mcrae_ewan: "We’re building a synthetic library of RNA sequence variants to map how mutations reshape RNA folding and function. By encoding thousands of designed variants in synthetic DNA, we aim to uncover design rules for RNA-based therapeutics and nanostructures." Like and repost if you like this idea! #SynBio #RootPath
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🚨 Today we’re launching something big:
Megabase Spark — RootPath’s new initiative to support bold, underfunded research with free synthetic DNA.
We’re giving away 3 million base pairs through 2026.
Details 👇 #MegabaseSpark
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